CytomX Therapeutics, Inc.

CytomX Therapeutics, Inc.

CTMXยทNASDAQ

$3.16

-6.7%
HealthcareBiotechnology

CytomX Therapeutics, Inc. operates as an oncology-focused biopharmaceutical company in the United States. The company develops antibody therapeutics based on its Probody technology platform for the treatment of cancer. The company's product candidates include CX-2009, an antibody drug conjugates (ADC) against CD166, which is in Phase II clinical trials for the treatment of breast cancer; CX-2029 that is in Phase II clinical trials for the treatment of squamous non-small cell lung cancer, head and neck squamous cell carcinoma, esophageal and gastro-esophageal junction cancers, and diffuse large B-cell lymphoma; BMS-986249, a CTLA-4 Probody therapeutic drug, which is in Phase I/II clinical trials for the treatment of metastatic melanoma; and BMS-986288, an anti-CTLA-4 Probody drug, which is in Phase I clinical trials for the treatment of solid tumors. It also develops CX-2043, a conditionally activated ADC targeting the epithelial cell adhesion molecule, as well as CX-904, a conditionally activated epidermal growth factor receptor for the treatment of solid tumor. The company has strategic collaborations with AbbVie Ireland Unlimited Company, Amgen, Inc., Bristol-Myers Squibb Company, ImmunoGen, Inc., Pfizer Inc., and Astellas Pharma Inc. to develop Probody therapeutics. CytomX Therapeutics, Inc. was founded in 2008 and is headquartered in South San Francisco, California.

At a Glance

Live Snapshot
Market Cap$508.20M
EPS-0.1500
P/E Ratio-33.83
Earnings Date08/06/2026
3Y+43.0%
5Y+11.0%
10Y+407.0%
3Y-83.0%
5Y-73.0%
10Y-71.0%
3Y-32.0%
5Y-1537.0%
10Y+3620.0%
CytomX Therapeutics, Inc.

CytomX Therapeutics, Inc. Profit Bridge

CTMX ยท NASDAQ
Revenue76.20M
Cost of Goods Sold (0.00)
Gross Profit76.20M
Operating Expenses (95.77M)
Operating Income-19.56M
Interest Expense (0.00)
Other Income/Expense2.43M
Pretax Income-17.13M
Income Tax (238.00K)
Net Income-17.37M
Net Income
-17.37M

Profitability Analysis

Gross Margin

100.0%

Exceptional pricing power and cost management. The company retains over half of revenue after direct costs.

Operating Margin

-25.7%

Operating losses indicate the core business is unprofitable. Requires restructuring or revenue growth.

Net Profit Margin

-22.8%

Net losses indicate the company is burning cash. Sustainability depends on path to profitability.

Profitability Insight

Margin squeeze alert: Healthy gross margins but weak operating margins suggest excessive operating expenses. Cost optimization could unlock significant value.

CytomX Therapeutics, Inc. Income Statement

CTMX โ€ข NASDAQ

CytomX Therapeutics, Inc. Income StatementDec 2025Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020Dec 2019Dec 2018Dec 2017Dec 2016Dec 2015Dec 2014Dec 2013
REVENUE
76.2M
138.1M
101.2M
53.2M
37.3M
68.4M
57.5M
59.5M
71.6M
15M
7.7M
5.1M
888K
GROSS PROFIT
76.2M
138.1M
101.2M
53.2M
37.3M
68.4M
57.5M
59.5M
71.6M
15M
7.7M
5.1M
888K
OPERATING INCOME
(95.8M)
(113.1M)
(107.7M)
(154.5M)
(153.4M)
(149M)
(168.4M)
(137.4M)
(117.9M)
(74.6M)
(40.9M)
(34.8M)
(15.8M)
(30M)
(29.7M)
(30M)
(42.8M)
(39.2M)
(36M)
(36.8M)
(33.5M)
(25.6M)
(19.9M)
(12.6M)
(6.5M)
(5M)
(65.8M)
(83.4M)
(77.7M)
(111.6M)
(114.2M)
(112.9M)
(131.6M)
(103.9M)
(92.3M)
(54.8M)
(28.4M)
(28.3M)
(10.9M)
-19.6M
25M
-6.5M
-101.3M
-116M
-80.5M
-110.9M
-77.9M
-46.3M
-59.6M
-33.2M
-29.8M
-15M
PRE-TAX INCOME
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(1.7M)
(1.7M)
(487K)
(254K)
5.2M
7.1M
9.8M
1.7M
255K
1.8M
8.4M
7.6M
2.7M
736K
-417K
-480K
-248K
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
-135K
-68K
-27K
-69K
(0.0)
-55K
(71K)
2.4M
7.1M
9.8M
2M
172K
29.6M
8.2M
7.6M
2.6M
667K
-2.2M
-535K
-177K
-17.1M
32.1M
3.3M
-99.3M
-115.9M
-50.9M
-102.7M
-70.3M
-43.6M
-58.9M
-35.4M
-30.3M
-15.1M
NET INCOME
(238K)
(224K)
(3.9M)
(0.0)
(0.0)
(13.9M)
-427K
(14.3M)
-513K
-19K
(10K)
(10K)
(10K)
-17.4M
31.9M
-569K
-99.3M
-115.9M
-64.8M
-102.2M
-84.6M
-43.1M
-58.9M
-35.4M
-30.3M
-15.1M

SEC Filings

CTMX - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
8-K

8-K 2026

N/A

June 03, 2026
May 29, 2026
2026
8-K

8-K 2026

N/A

May 07, 2026
May 07, 2026
2026
10-Q

10-Q 2026 Q1

Q1

May 07, 2026
March 31, 2026
2026
DEF 14A

DEF 14A 2026

N/A

April 30, 2026
June 17, 2026
2026
8-K

8-K 2026

N/A

March 19, 2026
March 17, 2026
2026
8-K

8-K 2026

N/A

March 16, 2026
March 16, 2026
2026
10-K

10-K 2025 FY

FY

March 16, 2026
December 31, 2025
2025
8-K

8-K 2025

N/A

November 06, 2025
November 06, 2025
2025
10-Q

10-Q 2025 Q3

Q3

November 06, 2025
September 30, 2025
2025
8-K

8-K 2025

N/A

August 13, 2025
August 13, 2025
2025
Showing 1 to 10 of 202 filings