Caribou Biosciences, Inc.

Caribou Biosciences, Inc.

CRBUยทNASDAQ

$2.00

-14%
HealthcareBiotechnology

Caribou Biosciences, Inc., a clinical-stage biopharmaceutical company, engages in the development of genome-edited allogeneic cell therapies for the treatment of hematologic malignancies and solid tumors in the United States and internationally. Its lead product candidates are CB-010, an allogeneic anti-CD19 CAR-T cell therapy that is in phase 1 clinical trial to treat relapsed or refractory B cell non-Hodgkin lymphoma; and CB-011, an allogeneic anti-BCMA CAR-T cell therapy for the treatment of relapsed or refractory multiple myeloma. The company also develops CB-012, an allogeneic anti-CD371 CAR-T cell therapy for the treatment of relapsed or refractory acute myeloid leukemia; and CB-020, an allogeneic CAR-NK cell therapy for the treatment of solid tumors. It has collaboration with AbbVie Manufacturing Management Unlimited Company to develop CAR-T cell therapies. The company was incorporated in 2011 and is headquartered in Berkeley, California.

At a Glance

Live Snapshot
Market Cap$198.36M
EPS-1.5900
P/E Ratio-1.26
Earnings Date08/11/2026
3Y-19.0%
5Y-10.0%
10Y+93.0%
3Y+49.0%
5Y+332.0%
10Y+532.0%
3Y+22.0%
5Y+234.0%
10Y+247.0%
Caribou Biosciences, Inc.

Caribou Biosciences, Inc. Profit Bridge

CRBU ยท NASDAQ
Revenue11.16M
Cost of Goods Sold (3.65M)
Gross Profit7.51M
Operating Expenses (143.71M)
Operating Income-136.19M
Interest Expense (0.00)
Other Income/Expense-12.48M
Pretax Income-148.68M
Income Tax (-550.00K)
Net Income-148.12M
Net Income
-148.12M

Profitability Analysis

Gross Margin

67.3%

Exceptional pricing power and cost management. The company retains over half of revenue after direct costs.

Operating Margin

-1220.5%

Operating losses indicate the core business is unprofitable. Requires restructuring or revenue growth.

Net Profit Margin

-1327.4%

Net losses indicate the company is burning cash. Sustainability depends on path to profitability.

Profitability Insight

Margin squeeze alert: Healthy gross margins but weak operating margins suggest excessive operating expenses. Cost optimization could unlock significant value.

Caribou Biosciences, Inc. Income Statement

CRBU โ€ข NASDAQ

Caribou Biosciences, Inc. Income StatementDec 2025Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020Dec 2019
REVENUE
11.2M
10M
34.5M
13.9M
9.6M
12.4M
5.8M
GROSS PROFIT
(3.6M)
(3.9M)
(3.5M)
(3.6M)
(984K)
(34.4M)
(23.6M)
7.5M
6.1M
31M
10.2M
8.6M
-22.1M
-17.8M
OPERATING INCOME
(143.7M)
(172.7M)
(147M)
(116.6M)
(75.6M)
(14.1M)
(40.1M)
(37.9M)
(46.5M)
(38.5M)
(38M)
(23.3M)
(14.1M)
(16.5M)
(109.4M)
(130.2M)
(112.1M)
(82.2M)
(52.3M)
(34.4M)
(23.6M)
-136.2M
-166.6M
-116.1M
-106.4M
-67M
-36.1M
-34.3M
PRE-TAX INCOME
(0.0)
(0.0)
(0.0)
(0.0)
(8K)
(20K)
(4K)
8M
0.0
10.7M
4.6M
140K
216K
1M
-3.6M
-3.9M
-3.5M
-3.6M
(0.0)
-34.4M
(0.0)
-12.5M
17.5M
14.2M
7M
377K
-3K
3.3M
-148.7M
-149.1M
-101.9M
-99.4M
-66.6M
-36.1M
-31M
NET INCOME
-550K
-9K
(193K)
(70K)
(321K)
-1.8M
-7.5M
-148.1M
-149.1M
-102.1M
-99.4M
-66.9M
-34.3M
-23.4M

SEC Filings

CRBU - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
8-K

8-K 2026

N/A

May 07, 2026
May 07, 2026
2026
10-Q

10-Q 2026 Q1

Q1

May 07, 2026
March 31, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 24, 2026
December 31, 2025
2025
8-K

8-K 2026

N/A

March 31, 2026
March 31, 2026
2026
10-K

10-K 2025 FY

FY

March 05, 2026
December 31, 2025
2025
8-K

8-K 2026

N/A

March 05, 2026
March 05, 2026
2026
10-Q

10-Q 2025 Q3

Q3

November 12, 2025
September 30, 2025
2025
8-K

8-K 2025

N/A

November 12, 2025
November 12, 2025
2025
8-K

8-K 2025

N/A

November 03, 2025
November 03, 2025
2025
10-Q

10-Q 2025 Q2

Q2

August 12, 2025
June 30, 2025
2025
Showing 1 to 10 of 103 filings