Caribou Biosciences, Inc.

Caribou Biosciences, Inc.

CRBUยทNASDAQ

$2.00

-14%
HealthcareBiotechnology

Caribou Biosciences, Inc., a clinical-stage biopharmaceutical company, engages in the development of genome-edited allogeneic cell therapies for the treatment of hematologic malignancies and solid tumors in the United States and internationally. Its lead product candidates are CB-010, an allogeneic anti-CD19 CAR-T cell therapy that is in phase 1 clinical trial to treat relapsed or refractory B cell non-Hodgkin lymphoma; and CB-011, an allogeneic anti-BCMA CAR-T cell therapy for the treatment of relapsed or refractory multiple myeloma. The company also develops CB-012, an allogeneic anti-CD371 CAR-T cell therapy for the treatment of relapsed or refractory acute myeloid leukemia; and CB-020, an allogeneic CAR-NK cell therapy for the treatment of solid tumors. It has collaboration with AbbVie Manufacturing Management Unlimited Company to develop CAR-T cell therapies. The company was incorporated in 2011 and is headquartered in Berkeley, California.

At a Glance

Live Snapshot
Market Cap$198.36M
EPS-1.5900
P/E Ratio-1.26
Earnings Date08/11/2026
crbu

Caribou Biosciences, Inc. Street Expectations Map

CRBU ยท NASDAQ

Wall Street analysts project that CRBU stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 5.00, with estimates ranging from a low of 3.00 to a high of 7.00.

Lowest Target
3.00
50.00%
Consensus Target
5.00
150.00%
Highest Target
7.00
250.00%

The consensus 1-year price target stands at 5.00, with estimates ranging from a low of 3.00 to a high of 7.00.

Analyst Consensus Analysis

Upside Potential

+150.0%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

80.0% spread

High uncertainty. Very wide target spread indicates significant disagreement among analystsโ€”major valuation uncertainty or transformation underway.

Analyst Conviction

Low

High uncertainty: Wide dispersion indicates analysts struggle to agree on valuationโ€”proceed with caution and independent analysis.

Market Sentiment Insight

High risk, high reward: Substantial upside potential exists, but wide analyst disagreement signals execution risk or unclear catalysts. Thorough due diligence essential before committing capital.

crbu

Caribou Biosciences, Inc. Forward Estimates of Revenue

CRBU ยท NASDAQ
Latest Revenue
11.16M
FY 2025
Avg Estimate
23.61M
FY 2026
Estimate Range
5.85M - 59.07M
Analyst Spread

Forward Growth Analysis

Projected Growth+111.6%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread225%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

crbu

Caribou Biosciences, Inc. Forward Estimates of Net Income

CRBU ยท NASDAQ
Latest Net Income
-148.12M
FY 2025
Avg Estimate
-125.20M
FY 2026
Estimate Range
-126.58M - -72.21M
Analyst Spread

Forward Growth Analysis

Projected Growth+15.5%

Solid growth trajectory indicates healthy business performance and competitive positioning.

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread43%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

crbu

Caribou Biosciences, Inc. Forward Estimates of EPS

CRBU ยท NASDAQ
Latest EPS
-1.59
FY 2025
Avg Estimate
$-1.16
FY 2026
Estimate Range
$-1.36 - $-0.77
Analyst Spread

Forward Growth Analysis

Projected Growth+27.4%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread50%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

crbu

Caribou Biosciences, Inc. Forward Estimates of EBIT

CRBU ยท NASDAQ
Latest EBIT
-136.19M
FY 2025
Avg Estimate
-23.61M
FY 2026
Estimate Range
-59.07M - -5.85M
Analyst Spread

Forward Growth Analysis

Projected Growth+82.7%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread225%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

crbu

Caribou Biosciences, Inc. Forward Estimates of EBITDA

CRBU ยท NASDAQ
Latest EBITDA
-132.55M
FY 2025
Avg Estimate
-23.61M
FY 2026
Estimate Range
-59.07M - -5.85M
Analyst Spread

Forward Growth Analysis

Projected Growth+82.2%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread225%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

crbu

Caribou Biosciences, Inc. Forward Estimates of SG&A Expense

CRBU ยท NASDAQ
Latest SG&A Expense
37.91M
FY 2025
Avg Estimate
67.71M
FY 2026
Estimate Range
16.77M - 169.40M
Analyst Spread

Forward Growth Analysis

Projected Growth+78.6%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread225%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

crbu

Caribou Biosciences, Inc. Insider Positioning

CRBU ยท NASDAQ

During the last 12 months, insiders have sold $47K worth of CRBU shares, with no buying activity reported.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

0

0.00

Sold

24.3K

47.47K

Net Activity

-47K

-$47K

6-9 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

No buying activity

Top Sellers

1
KTP

Kelly Timothy P

Officer: Chief Technology Officer

9.4K sharesโ€ข2 transactions

$18K

2
KRA

Khan Ruhi Ahmad

Officer: Chief Business Officer

6.9K sharesโ€ข1 transactions

$14K

3
MBG

Mcclung Barbara G

Officer: Chief Legal Officer

6.9K sharesโ€ข1 transactions

$14K

4
ATM

Albertson Tina M.

Officer: Chief Medical Officer

1.1K sharesโ€ข1 transactions

$2K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $47K net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Insider Participation

High Selling

4 insider sellers vs. 0 buyers. Widespread selling across multiple insiders may signal concerns.