CareDx, Inc

CareDx, Inc

CDNAยทNASDAQ

$22.31

+1.1%
HealthcareMedical - Diagnostics & Research

CareDx, Inc. discovers, develops, and commercializes diagnostic solutions for transplant patients and caregivers worldwide. It provides AlloSure Kidney, a donor-derived cell-free DNA (dd-cfDNA) solution for kidney transplant patients; AlloMap Heart, a gene expression solution for heart transplant patients; AlloSure Heart, a dd-cfDNA solution for heart transplant patients; and AlloSure Lung, a dd-cfDNA solution for lung transplant patients. The company also offers TruSight HLA, a next generation sequencing (NGS) based high resolution typing solution; Olerup SSP, which is used to type human leukocyte antigen (HLA) alleles based on sequence specific primer technology; QTYPE that enables precision in HLA typing; and Ottr, a transplant patient management software. In addition, it provides AlloSeq Tx, a high-resolution HLA typing solution; AlloSeq cfDNA, a surveillance solution to measure dd-cfDNA in blood; AlloSeq HCT, a solution for chimerism testing for stem cell transplant recipients; and XynQAPI transplant quality tracking and waitlist management solutions, as well as AlloCare, a mobile app that offers a patient-centric resource for transplant recipients. The company offers its products directly to customers, as well as through third-party distributors and sub-distributors. It has a license agreement with Illumina, Inc. for the distribution, development, and commercialization of NGS products and technologies; and Cibiltech SAS to commercialize iBox, a software for the predictive analysis of post-transplantation kidney allograft loss. The company was formerly known as XDx, Inc. and changed its name to CareDx, Inc. in March 2014. The company was incorporated in 1998 and is headquartered in South San Francisco, California.

At a Glance

Live Snapshot
Market Cap$1.15B
EPS-0.4000
P/E Ratio-55.77
Earnings Date08/05/2026

Intrinsic Alpha Methodology

Thesis Lenses

Signal ยท Driver ยท Risk

Signal

Medium confidence

Valuation multiple is compressed (P/E -55.8).

Valuation inputs: P/E -55.8, earnings yield N/A, momentum +1.1%.

If multiples stay elevated while momentum fades, downside repricing risk rises.

Driver

High confidence

Return profile is soft (ROE -7.0%, ROIC -6.5%).

Profitability stack: net margin -5.6%, ROE -7.0%, ROIC -6.5%.

Quality deterioration often appears in margins before it shows up in headline EPS.

Risk

High confidence

Risk profile is balanced but has notable pressure points to monitor.

Risk factors: liabilities/assets +26.7%, momentum +1.1%, net margin -5.6%.

Higher leverage with weak momentum and thin margins can amplify drawdown severity.

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CareDx, Inc Market vs Earnings Trajectory

CDNA ยท NASDAQ

Loading price and EPS data...

CareDx, Inc

CareDx, Inc Fair Value Envelope

CDNA ยท NASDAQ

Our analysis suggests that CDNA has a fair value of HIDDEN per share in the Base Case projection. With shares currently trading at $22.31, this represents a potential HIDDEN relative to our calculated worth for CareDx, Inc.

Intrinsic Value
Current Price: $22.31
3Y-72.0%
5Y-
10Y-83.0%
3Y+18.0%
5Y+98.0%
10Y+835.0%
3Y-72.0%
5Y+14.0%
10Y-46.0%
3Y-267.0%
5Y+26.0%
10Y-354.0%
3Y-173.0%
5Y+57.0%
10Y-312.0%
3Y-24.0%
5Y+12.0%
10Y+439.0%
CareDx, Inc

CareDx, Inc Profit Bridge

CDNA ยท NASDAQ
Revenue379.81M
Cost of Goods Sold (125.38M)
Gross Profit254.43M
Operating Expenses (275.44M)
Operating Income-21.02M
Interest Expense (0.00)
Other Income/Expense-67.00K
Pretax Income-21.08M
Income Tax (271.00K)
Net Income-21.35M
Net Income
-21.35M

Profitability Analysis

Gross Margin

67.0%

Exceptional pricing power and cost management. The company retains over half of revenue after direct costs.

Operating Margin

-5.5%

Operating losses indicate the core business is unprofitable. Requires restructuring or revenue growth.

Net Profit Margin

-5.6%

Net losses indicate the company is burning cash. Sustainability depends on path to profitability.

Profitability Insight

Margin squeeze alert: Healthy gross margins but weak operating margins suggest excessive operating expenses. Cost optimization could unlock significant value.

66.99%
Gross Profit Margin
3Y+3.0%
5Y-
10Y+40.0%
-5.53%
Operating Profit Margin
-145%
3Y-77.0%
5Y-53.0%
10Y-94.0%
-5.62%
Net Profit Margin
-136%
3Y-76.0%
5Y-42.0%
10Y-94.0%
-7.05%
Return on Equity
-151%
3Y-60.0%
5Y+5.0%
10Y-97.0%
-5.17%
Return on Assets
-148%
3Y-63.0%
5Y+2.0%
10Y-90.0%
-6.50%
Return on Invested Capital
-165%
3Y-60.0%
5Y-8.0%
10Y-89.0%
CDNA

CareDx, Inc Cash Conversion Engine

CDNA ยท NASDAQ
Net Income-21.35M
Depreciation & Amortization20.42M
Stock-Based Compensation34.86M
Change in Working Capital3.81M
Others4.28M
Capital Expenditures-5.91M
Free Cash Flow36.12M

Cash Flow Quality Analysis

FCF Conversion Rate

-169.1%

Negative free cash flow despite positive earnings raises concerns about cash generation ability or heavy capital requirements.

CapEx Intensity

14.1%

Asset-light business model. Low capital requirements leave more cash available for shareholders and growth investments.

FCF Growth Trend

+14.4%

Steady FCF growth indicates consistent cash generation improvement. On a positive trajectory.

Working Capital Impact

+$3.81M

Working capital inflow boosted cash flow. Efficient management of receivables, inventory, and payables contributing positively.

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CareDx, Inc Funding & Solvency Profile

CDNA ยท NASDAQ
Cash & Cash Equivalents77.92M
Net Receivables44.59M
Inventory26.40M
Other Current Assets11.23M
Total Current Assets269 M
Property, Plant & Equipment54.36M
Goodwill & Intangible Assets72.44M
Long-Term Investments0.00
Other Non-Current Assets14.87M
Total Non-Current Assets69 M
Total Assets
411.06M

Financial Health Analysis

Current Ratio

3.40x

Excellent liquidity position. The company can easily cover its short-term obligations with substantial cushion.

Debt-to-Equity Ratio

0.31x

Conservative capital structure. The company relies primarily on equity financing, indicating low financial risk.

Working Capital

190 M

Strong working capital position provides significant operational flexibility and financial cushion.

Asset Composition

66% Current

Asset-light business model with high liquidity. Majority of assets are easily convertible to cash.

Financial Health Insight

Strong financial foundation: Excellent liquidity combined with conservative leverage suggests the company is well-positioned to weather economic uncertainties and fund growth opportunities.

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CareDx, Inc Street Expectations Map

CDNA ยท NASDAQ

Wall Street analysts project that CDNA stock may experience modest gains over the coming 12 months. The consensus 1-year price target stands at 24.00, with estimates ranging from a low of 18.00 to a high of 28.00.

Lowest Target
18.00
-19.32%
Consensus Target
24.00
7.58%
Highest Target
28.00
25.50%

The consensus 1-year price target stands at 24.00, with estimates ranging from a low of 18.00 to a high of 28.00.

Analyst Consensus Analysis

Upside Potential

+7.6%

Moderate upside. Analysts expect positive returns but with limited margin of safety. Consider entry timing.

Analyst Agreement

41.7% spread

Mixed analyst views. Wide target range suggests differing opinions on key value drivers, growth prospects, or risk factors.

Risk-Reward Profile

1.32x

Balanced risk-reward. Upside and downside potential relatively symmetric. Suitable for moderate risk tolerance with conviction in thesis.

Analyst Conviction

Moderate

Neutral sentiment. Fair value pricing with moderate agreement suggests wait-and-see approach or catalyst-driven opportunity.

Market Sentiment Insight

Monitor and evaluate: Current analyst consensus suggests limited conviction or near-term catalysts. Stay informed on company developments and reassess positioning as new information emerges.

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CareDx, Inc Insider Positioning

CDNA ยท NASDAQ

During the last 12 months, insiders have sold $1.46M worth of CDNA shares, with no buying activity reported.

3 Months

Bought

0

0.00

Sold

23.5K

487.41K

Net Activity

-487K

-$487K

3-6 Months

Bought

0

0.00

Sold

34.1K

717.31K

Net Activity

-717K

-$717K

6-9 Months

Bought

0

0.00

Sold

14.7K

250.60K

Net Activity

-251K

-$251K

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

No buying activity

Top Sellers

1
HJWJ

Hanna John Walter Jr

Director, Officer: President And Ceo

39.9K sharesโ€ข4 transactions

$843K

2
NJA

Novack Jeffrey Adam

Officer: Secretary And General Counsel

21.8K sharesโ€ข6 transactions

$397K

3
TAA

Torres Arthur A

Director

10.6K sharesโ€ข2 transactions

$215K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $1.46M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$487K

Heavy recent selling activity. Recent insider sales notably exceed purchasesโ€”may warrant investigation into company developments.

Insider Participation

High Selling

3 insider sellers vs. 0 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.

0.00%
Dividend Yield
3Y-
5Y-
10Y-
ย 

cdna Dividend History

CDNA
10Y CAGR +0%
Latest $0
Annual $0
Stable dividend payments
Last Period: +0%