Cabaletta Bio, Inc.

Cabaletta Bio, Inc.

CABA·NASDAQ

$3.42

-7.2%
HealthcareBiotechnology

Cabaletta Bio, Inc., a clinical-stage biotechnology company, focuses on the discovery and development of engineered T cell therapies for patients with B cell-mediated autoimmune diseases. Its proprietary technology utilizes chimeric autoantibody receptor (CAAR) T cells that are designed to selectively bind and eliminate B cells, which produce disease-causing autoantibodies or pathogenic B cells. The company's lead product candidate is DSG3-CAART, which is in Phase I clinical trial for the treatment of mucosal pemphigus vulgaris, an autoimmune blistering skin disease, and Hemophilia A with Factor VIII alloantibodies. Its product candidate pipeline also includes MuSK-CAART, a preclinical stage product to treat a subset of patients with myasthenia gravis; FVIII-CAART, a discovery stage product to treat a subset of patients with Hemophilia A; and DSG3/1-CAART, a discovery stage product for the treatment of mucocutaneous pemphigus vulgaris. It has a collaboration with the University of Pennsylvania; and research agreement with The Regents of the University of California. The company was formerly known as Tycho Therapeutics, Inc. and changed its name to Cabaletta Bio, Inc. in August 2018. Cabaletta Bio, Inc. was incorporated in 2017 and is headquartered in Philadelphia, Pennsylvania.

At a Glance

Live Snapshot
Market Cap$556.83M
EPS-1.6400
P/E Ratio-2.08
Earnings Date08/06/2026
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Cabaletta Bio, Inc. Street Expectations Map

CABA · NASDAQ

Wall Street analysts project that CABA stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 16.33, with estimates ranging from a low of 3.00 to a high of 32.00.

Lowest Target
3.00
-12.15%
Consensus Target
16.33
378.18%
Highest Target
32.00
837.04%

The consensus 1-year price target stands at 16.33, with estimates ranging from a low of 3.00 to a high of 32.00.

Analyst Consensus Analysis

Upside Potential

+378.2%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

177.6% spread

High uncertainty. Very wide target spread indicates significant disagreement among analysts—major valuation uncertainty or transformation underway.

Risk-Reward Profile

68.88x

Favorable risk-reward. Potential upside significantly exceeds downside risk, offering asymmetric return profile attractive for risk-tolerant investors.

Analyst Conviction

Low

High uncertainty: Wide dispersion indicates analysts struggle to agree on valuation—proceed with caution and independent analysis.

Market Sentiment Insight

High risk, high reward: Substantial upside potential exists, but wide analyst disagreement signals execution risk or unclear catalysts. Thorough due diligence essential before committing capital.

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Cabaletta Bio, Inc. Forward Estimates of Revenue

CABA · NASDAQ
Latest Revenue
0.00
FY 2025
Avg Estimate
2.50M
FY 2026
Estimate Range
2.50M - 2.50M
Analyst Spread

Forward Growth Analysis

Analyst Coverage6 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

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Cabaletta Bio, Inc. Forward Estimates of Net Income

CABA · NASDAQ
Latest Net Income
-167.86M
FY 2025
Avg Estimate
-135.20M
FY 2026
Estimate Range
-167.98M - -102.43M
Analyst Spread

Forward Growth Analysis

Projected Growth+19.5%

Solid growth trajectory indicates healthy business performance and competitive positioning.

Analyst Coverage6 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread48%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomes—suggests elevated risk and potential volatility.

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Cabaletta Bio, Inc. Forward Estimates of EPS

CABA · NASDAQ
Latest EPS
-1.64
FY 2025
Avg Estimate
$-1.38
FY 2026
Estimate Range
$-1.64 - $-1.00
Analyst Spread

Forward Growth Analysis

Projected Growth+15.7%

Solid growth trajectory indicates healthy business performance and competitive positioning.

Analyst Coverage5 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread46%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomes—suggests elevated risk and potential volatility.

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Cabaletta Bio, Inc. Forward Estimates of EBIT

CABA · NASDAQ
Latest EBIT
-172.24M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage6 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

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Cabaletta Bio, Inc. Forward Estimates of EBITDA

CABA · NASDAQ
Latest EBITDA
-170.59M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage6 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

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Cabaletta Bio, Inc. Forward Estimates of SG&A Expense

CABA · NASDAQ
Latest SG&A Expense
29.57M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth-100.0%

Significant contraction projected—major business challenges or industry disruption likely.

Analyst Coverage6 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

OutlookCautious

Analyst skepticism evident—carefully evaluate risks before investment decisions.

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Cabaletta Bio, Inc. Insider Positioning

CABA · NASDAQ

During the last 12 months, insiders have purchased $557K worth of CABA shares, with no selling activity reported.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

132.1K

296.19K

Sold

0

0.00

Net Activity

+296K

+$296K

6-9 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

9-12 Months

Bought

110.0K

260.70K

Sold

0

0.00

Net Activity

+261K

+$261K

Top Buyers

1
TS

Tomasello Shawn

Director

44.7K shares2 transactions

$102K

2
NS

Nichtberger Steven

Director, Officer: President & Ceo

45.0K shares1 transactions

$101K

3
SM

Simon Mark

Director

33.1K shares2 transactions

$77K

4
BC

Bollard Catherine

Director

26.4K shares2 transactions

$62K

5
HRCJ

Henriques Richard C Jr

Director

22.0K shares1 transactions

$52K

Top Sellers

No selling activity

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $557K net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

∞:1

Perfect buy/sell ratio. Only buying activity with zero selling—the most bullish possible insider signal.

Insider Participation

High Buying

5 insider buyers vs. 0 sellers. Broad-based buying across management team suggests widespread confidence.

Insider Activity Insight

Compelling insider conviction: The combination of strong buy/sell ratio and multiple buyers suggests insiders see attractive risk/reward. Consider this alongside fundamental analysis for confirmation.