Applied Therapeutics, Inc.

Applied Therapeutics, Inc.

APLT·NASDAQ

$0.91

+0.0000%
HealthcareBiotechnology

Applied Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops novel products to target cardiovascular disease, galactosemia, and diabetic complications. Its lead product candidate is AT-007 that has completed phase 1/2 for the treatment of galactosemia in healthy volunteers and adults, as well as is in pediatric clinical study for the treatment of galactosemia in kids; for treating sorbitol dehydrogenase deficiency; and for the treatment of phosphomannomutase enzyme-CDG. The company also develops AT-001 that is in phase III clinical trials for treating diabetic cardiomyopathy, as well as for the treatment of diabetic peripheral neuropathy. Its preclinical stage products include AT-003 for the treatment diabetic retinopathy; AT-104, a PI3K inhibitor for treating orphan hematological oncology T Cell Acute Lymphoblastic Leukemia. Applied Therapeutics, Inc. was incorporated in 2016 and is headquartered in New York, New York.

At a Glance

Live Snapshot
Market Cap$131.07M
EPS-0.7600
P/E Ratio-1.13
Earnings Date11/13/2025
-174.41%
Return on Invested Capital
-142%
3Y+7.0%
5Y+34.0%
10Y-7.0%
-185.29%
Return on Equity
-127%
3Y+10.0%
5Y+33.0%
10Y-271.0%
-121.84%
Return on Assets
-44%
3Y+4.0%
5Y+30.0%
10Y-7.0%
Applied Therapeutics, Inc.

Applied Therapeutics, Inc. Management Team

APLT · NASDAQ
MC

Mr. Corwin Dale Hooks

Chief Commercial Officer

Compensation

$636,739

Born 1967(Age 59)
male
DR

Dr. Riccardo Perfetti M.D., Ph.D.

Chief Medical Officer

Compensation

$860,761

Born 1960(Age 66)
MC

Mr. Constantine Chinoporos

Chief Operating Officer & Chief Business Officer

Born 1966(Age 60)
male
DT

Dr. Todd F. Baumgartner M.D., M.P.H.

Chief Regulatory Officer

MJ

Mr. John H. Johnson

Executive Chairman

Compensation

$378,840

Born 1958(Age 68)
male
MR

Ms. Reena Thomas Colacot

Head of Quality

female
MC

Ms. Catherine Thorpe

Interim Chief Accounting Officer

Born 1964(Age 62)
female
ML

Mr. Les D. Funtleyder

Interm Chief Executive Officer, Chief Financial Officer, Principal Financial Officer & Director

Compensation

$768,846

Born 1970(Age 56)
male
aplt

Applied Therapeutics, Inc. Insider Positioning

APLT · NASDAQ

During the last 12 months, insiders have purchased $237K and sold $7K worth of APLT shares, resulting in $230K of net buying activity.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

9-12 Months

Bought

600.0K

237.00K

Sold

4.9K

7.32K

Net Activity

+230K

+$230K

Top Buyers

1
LT

Lerner Teena

Director

200.0K shares1 transactions

$79K

2
KSJ

Kanter Stacy J.

Director

200.0K shares1 transactions

$79K

3
SJS

Skyler Jay S

Director

200.0K shares1 transactions

$79K

Top Sellers

1
BEP

Bailey Evan Prescott

Officer: Chief Medical Officer

4.9K shares1 transactions

$7K

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $230K net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

32.36:1

Exceptional buy/sell ratio. Buying dramatically outweighs selling—one of the strongest possible insider signals.

Insider Participation

High Buying

3 insider buyers vs. 1 sellers. Broad-based buying across management team suggests widespread confidence.

Insider Activity Insight

Compelling insider conviction: The combination of strong buy/sell ratio and multiple buyers suggests insiders see attractive risk/reward. Consider this alongside fundamental analysis for confirmation.

SEC Filings

APLT - Filing history and reports

No SEC filings available for APLT