Applied Therapeutics, Inc.

Applied Therapeutics, Inc.

APLT·NASDAQ

$0.91

+0.0000%
HealthcareBiotechnology

Applied Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops novel products to target cardiovascular disease, galactosemia, and diabetic complications. Its lead product candidate is AT-007 that has completed phase 1/2 for the treatment of galactosemia in healthy volunteers and adults, as well as is in pediatric clinical study for the treatment of galactosemia in kids; for treating sorbitol dehydrogenase deficiency; and for the treatment of phosphomannomutase enzyme-CDG. The company also develops AT-001 that is in phase III clinical trials for treating diabetic cardiomyopathy, as well as for the treatment of diabetic peripheral neuropathy. Its preclinical stage products include AT-003 for the treatment diabetic retinopathy; AT-104, a PI3K inhibitor for treating orphan hematological oncology T Cell Acute Lymphoblastic Leukemia. Applied Therapeutics, Inc. was incorporated in 2016 and is headquartered in New York, New York.

At a Glance

Live Snapshot
Market Cap$131.07M
EPS-0.7600
P/E Ratio-1.13
Earnings Date11/13/2025
aplt

Applied Therapeutics, Inc. Street Expectations Map

APLT · NASDAQ

Wall Street analysts project that APLT stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 4.50, with estimates ranging from a low of 4.00 to a high of 5.00.

Lowest Target
4.00
339.51%
Consensus Target
4.50
394.45%
Highest Target
5.00
449.39%

The consensus 1-year price target stands at 4.50, with estimates ranging from a low of 4.00 to a high of 5.00.

Analyst Consensus Analysis

Upside Potential

+394.4%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

22.2% spread

Good consensus alignment. Moderate target spread reflects general agreement on value drivers with some variance in assumptions.

Analyst Conviction

Very High

Strong buy conviction: High upside with tight consensus suggests compelling investment opportunity backed by analyst confidence.

Market Sentiment Insight

Rare opportunity: Exceptional upside potential with strong analyst consensus creates a compelling setup. The combination of significant price target premium and tight agreement suggests high-conviction undervaluation that may attract institutional capital.

aplt

Applied Therapeutics, Inc. Forward Estimates of Revenue

APLT · NASDAQ
Latest Revenue
455.00K
FY 2024
Avg Estimate
333.33K
FY 2025
Estimate Range
153.65K - 513.02K
Analyst Spread

Forward Growth Analysis

Projected Growth-26.7%

Significant contraction projected—major business challenges or industry disruption likely.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread108%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evident—carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertainty—exercise caution.

aplt

Applied Therapeutics, Inc. Forward Estimates of Net Income

APLT · NASDAQ
Latest Net Income
-105.62M
FY 2024
Avg Estimate
-79.82M
FY 2025
Estimate Range
-82.53M - -77.12M
Analyst Spread

Forward Growth Analysis

Projected Growth+24.4%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread7%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

aplt

Applied Therapeutics, Inc. Forward Estimates of EPS

APLT · NASDAQ
Latest EPS
-0.76
FY 2024
Avg Estimate
$-0.57
FY 2025
Estimate Range
$-0.59 - $-0.55
Analyst Spread

Forward Growth Analysis

Projected Growth+24.7%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage2 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread7%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

aplt

Applied Therapeutics, Inc. Forward Estimates of EBIT

APLT · NASDAQ
Latest EBIT
-104.30M
FY 2024
Avg Estimate
66.67K
FY 2025
Estimate Range
30.73K - 102.60K
Analyst Spread

Forward Growth Analysis

Projected Growth+100.1%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread108%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

aplt

Applied Therapeutics, Inc. Forward Estimates of EBITDA

APLT · NASDAQ
Latest EBITDA
-103.87M
FY 2024
Avg Estimate
66.67K
FY 2025
Estimate Range
30.73K - 102.60K
Analyst Spread

Forward Growth Analysis

Projected Growth+100.1%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread108%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

aplt

Applied Therapeutics, Inc. Forward Estimates of SG&A Expense

APLT · NASDAQ
Latest SG&A Expense
56.01M
FY 2024
Avg Estimate
8.54M
FY 2025
Estimate Range
3.94M - 13.15M
Analyst Spread

Forward Growth Analysis

Projected Growth-84.7%

Significant contraction projected—major business challenges or industry disruption likely.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread108%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evident—carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertainty—exercise caution.

aplt

Applied Therapeutics, Inc. Insider Positioning

APLT · NASDAQ

During the last 12 months, insiders have purchased $237K and sold $7K worth of APLT shares, resulting in $230K of net buying activity.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

9-12 Months

Bought

600.0K

237.00K

Sold

4.9K

7.32K

Net Activity

+230K

+$230K

Top Buyers

1
LT

Lerner Teena

Director

200.0K shares1 transactions

$79K

2
KSJ

Kanter Stacy J.

Director

200.0K shares1 transactions

$79K

3
SJS

Skyler Jay S

Director

200.0K shares1 transactions

$79K

Top Sellers

1
BEP

Bailey Evan Prescott

Officer: Chief Medical Officer

4.9K shares1 transactions

$7K

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $230K net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

32.36:1

Exceptional buy/sell ratio. Buying dramatically outweighs selling—one of the strongest possible insider signals.

Insider Participation

High Buying

3 insider buyers vs. 1 sellers. Broad-based buying across management team suggests widespread confidence.

Insider Activity Insight

Compelling insider conviction: The combination of strong buy/sell ratio and multiple buyers suggests insiders see attractive risk/reward. Consider this alongside fundamental analysis for confirmation.