AnaptysBio, Inc.

AnaptysBio, Inc.

ANAB·NASDAQ

$51.24

-3.6%
HealthcareBiotechnology

AnaptysBio, Inc., a clinical stage biotechnology company, engages in developing therapeutic product candidates for inflammation and immuno-oncology indications. Its products include Imsidolimab, an antibody that inhibits the interleukin-36 receptor (IL-36R) for the treatment of various dermatological inflammatory diseases; Rosnilimab, an anti-PD-1 agonist antibody program designed to augment PD-1 signaling through rosnilimab treatment to suppress T-cell driven human inflammatory diseases; and ANB032, an anti-BTLA modulator antibody applicable to human inflammatory diseases associated with lymphoid and myeloid immune cell dysregulation. The company also focuses on developing various antibody programs that are advanced to preclinical and clinical milestones under its collaborations. It has a collaboration and license agreement with GlaxoSmithKline, Inc. and Bristol-Myers Squibb; and license agreements with United Kingdom Research and Innovation, as well as Millipore Corporation. The company was formerly known as Anaptys Biosciences, Inc. and changed its name to AnaptysBio, Inc. in July 2006. AnaptysBio, Inc. was incorporated in 2005 and is based in San Diego, California.

At a Glance

Live Snapshot
Market Cap$2.21B
EPS-0.4600
P/E Ratio-111.39
Earnings Date08/05/2026
14.61%
Return on Invested Capital
-156%
3Y-174.0%
5Y-343.0%
10Y-373.0%
-35.56%
Return on Equity
-83%
3Y-28.0%
5Y+608.0%
10Y+228.0%
-3.63%
Return on Assets
-88%
3Y-83.0%
5Y-24.0%
10Y-47.0%
AnaptysBio, Inc.

AnaptysBio, Inc. Management Team

ANAB · NASDAQ
MB

Mr. Benjamin Stone

Chief Business Officer

male
MD

Mr. Dennis M. Mulroy

Chief Financial Officer

Compensation

$673,635

Born 1955(Age 71)
male
ME

Mr. Eric J. Loumeau

Chief Legal Officer

Compensation

$722,002

Born 1963(Age 63)
male
DP

Dr. Paul F. Lizzul FAAD, M.B.A., M.D., M.P.H., Ph.D.

Chief Medical Officer

Compensation

$712,559

Born 1975(Age 51)
MD

Mr. Daniel R. Faga

President, Chief Executive Officer & Director

Compensation

$1,017,710

Born 1980(Age 46)
male
MD

Mr. Douglas A. Rich M.B.A.

Senior Vice President of CMC

Born 1969(Age 57)
male
MP

Ms. Priya Raina

Senior Vice President of Clinical Operations

female
MM

Ms. Monique Da Silva

Senior Vice President of Corporate Affairs

female
MB

Ms. Beth Mueller

Senior Vice President of Human Resources

female
DM

Dr. Martin Dahl Ph.D.

Senior Vice President of Research

anab

AnaptysBio, Inc. Insider Positioning

ANAB · NASDAQ

During the last 12 months, insiders have sold $4.54M worth of ANAB shares, with no buying activity reported.

3 Months

Bought

0

0.00

Sold

13.1K

730.58K

Net Activity

-731K

-$731K

3-6 Months

Bought

0

0.00

Sold

77.7K

3.74M

Net Activity

-3.7M

-$3.74M

6-9 Months

Bought

0

0.00

Sold

5.0K

70.10K

Net Activity

-70K

-$70K

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

No buying activity

Top Sellers

1
LEJ

Loumeau Eric J

Officer: Chief Legal Officer

37.5K shares6 transactions

$1.68M

2
SJP

Schmid John P.

Director

12.6K shares1 transactions

$702K

3
FD

Faga Daniel

Director, Officer: President, Ceo

14.8K shares2 transactions

$667K

4
MD

Mulroy Dennis

Officer: Chief Financial Officer

12.5K shares2 transactions

$612K

5
MM

Marquet Magda

Director

9.3K shares1 transactions

$447K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $4.54M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$731K

Heavy recent selling activity. Recent insider sales notably exceed purchases—may warrant investigation into company developments.

Insider Participation

High Selling

5 insider sellers vs. 0 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.

SEC Filings

ANAB - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2025

N/A

April 29, 2025
June 17, 2025
2025
DEF 14A

DEF 14A 2024

N/A

April 24, 2024
June 12, 2024
2024
DEF 14A

DEF 14A 2023

N/A

April 27, 2023
June 15, 2023
2023
DEF 14A

DEF 14A 2022

N/A

April 29, 2022
June 23, 2022
2022
DEF 14A

DEF 14A 2021

N/A

April 26, 2021
June 17, 2021
2021
DEF 14A

DEF 14A 2020

N/A

April 27, 2020
June 19, 2020
2020
DEF 14A

DEF 14A 2018

N/A

April 26, 2019
December 31, 2018
2018
DEF 14A

DEF 14A 2018

N/A

April 26, 2018
June 12, 2018
2018
Showing 1 to 8 of 8 filings