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Actuate Therapeutics Inc

ACTU·NASDAQ

$2.11

-4.5%
HealthcareBiotechnology

Actuate Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing therapies for the treatment of cancers. The company's lead product candidate is Elraglusib Injection, a novel glycogen synthase kinase-3 inhibitor to treat metastatic pancreatic ductal adenocarcinoma. It also develops Elraglusib for the treatment of Ewing sarcoma, metastatic melanoma, and colorectal cancer. The company was formerly known as Apotheca Therapeutics, Inc. and changed its name to Actuate Therapeutics, Inc. in October 2015. The company was incorporated in 2015 and is based in Fort Worth, Texas.

At a Glance

Live Snapshot
Market Cap$50.48M
EPS-1.0600
P/E Ratio-5.79
Earnings Date06/03/2026
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Actuate Therapeutics Inc Street Expectations Map

ACTU · NASDAQ

Wall Street analysts project that ACTU stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 21.00, with estimates ranging from a low of 21.00 to a high of 21.00.

Lowest Target
21.00
895.26%
Consensus Target
21.00
895.26%
Highest Target
21.00
895.26%

The consensus 1-year price target stands at 21.00, with estimates ranging from a low of 21.00 to a high of 21.00.

Analyst Consensus Analysis

Upside Potential

+895.3%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

0.0% spread

High analyst agreement. Narrow target range indicates strong consensus on valuation, suggesting clear investment thesis and predictable outlook.

Analyst Conviction

Very High

Strong buy conviction: High upside with tight consensus suggests compelling investment opportunity backed by analyst confidence.

Market Sentiment Insight

Rare opportunity: Exceptional upside potential with strong analyst consensus creates a compelling setup. The combination of significant price target premium and tight agreement suggests high-conviction undervaluation that may attract institutional capital.

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Actuate Therapeutics Inc Forward Estimates of Revenue

ACTU · NASDAQ
Latest Revenue
0.00
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

OutlookCautious

Analyst skepticism evident—carefully evaluate risks before investment decisions.

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Actuate Therapeutics Inc Forward Estimates of Net Income

ACTU · NASDAQ
Latest Net Income
-22.23M
FY 2025
Avg Estimate
-22.18M
FY 2026
Estimate Range
-24.25M - -20.11M
Analyst Spread

Forward Growth Analysis

Projected Growth+0.2%

Flat growth suggests market maturity or near-term challenges offsetting expansion efforts.

Estimate Spread19%

Reasonable estimate spread indicates general agreement with normal forecast variance.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

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Actuate Therapeutics Inc Forward Estimates of EPS

ACTU · NASDAQ
Latest EPS
-1.06
FY 2025
Avg Estimate
$-1.14
FY 2026
Estimate Range
$-1.24 - $-1.03
Analyst Spread

Forward Growth Analysis

Projected Growth-7.2%

Declining expectations indicate headwinds—investigate whether temporary or structural issues.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread19%

Reasonable estimate spread indicates general agreement with normal forecast variance.

OutlookCautious

Analyst skepticism evident—carefully evaluate risks before investment decisions.

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Actuate Therapeutics Inc Forward Estimates of EBIT

ACTU · NASDAQ
Latest EBIT
-22.49M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

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Actuate Therapeutics Inc Forward Estimates of EBITDA

ACTU · NASDAQ
Latest EBITDA
-22.50M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

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Actuate Therapeutics Inc Forward Estimates of SG&A Expense

ACTU · NASDAQ
Latest SG&A Expense
12.20M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth-100.0%

Significant contraction projected—major business challenges or industry disruption likely.

OutlookCautious

Analyst skepticism evident—carefully evaluate risks before investment decisions.

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Actuate Therapeutics Inc Insider Positioning

ACTU · NASDAQ

During the last 12 months, insiders have purchased $1.50M and sold $1.62M worth of ACTU shares, resulting in $124K of net selling activity.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

0

0.00

Sold

280.0K

1.62M

Net Activity

-1.6M

-$1.62M

6-9 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

9-12 Months

Bought

214.3K

1.50M

Sold

0

0.00

Net Activity

+1.5M

+$1.50M

Top Buyers

1
KLW

Kreis Leslie W.

Director, 10 Percent Owner:

71.4K shares1 transactions

$500K

2
BECL

Bios Equity Cof, Lp

Director, 10 Percent Owner:

71.4K shares1 transactions

$500K

3
FAG

Fletcher Aaron G.L.

Director, 10 Percent Owner:

71.4K shares1 transactions

$500K

Top Sellers

1
TTS

Thomson Todd S

Director, 10 Percent Owner:

280.0K shares1 transactions

$1.62M

Insider Activity Analysis

Net Insider Sentiment

Bearish

Slightly bearish with $124K net selling. Selling modestly exceeds buying, which could be routine diversification rather than concern.

Buy/Sell Ratio

0.92:1

Moderately negative ratio. Selling is roughly double the buying, which may be routine or signal caution.

Insider Participation

High Buying

3 insider buyers vs. 1 sellers. Broad-based buying across management team suggests widespread confidence.

Insider Activity Insight

Balanced insider activity: Roughly equal buying and selling suggests normal portfolio management rather than strong directional signals. Look to other metrics for clearer investment insights.