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Acrivon Therapeutics, Inc. Common Stock

ACRV·NASDAQ

$1.60

-1.8%
HealthcareBiotechnology

Acrivon Therapeutics, Inc., a clinical stage biopharmaceutical company, engages in developing oncology medicines for the patients whose tumors are predicted to be sensitive to each specific medicine by utilizing its proteomics-based patient responder identification platform. The company's Acrivon Predictive Precision Proteomics, a precision medicine platform enables the creation of drug specific proprietary OncoSignature companion diagnostics that are used to identify the patients to benefit from its drug candidates. Its lead clinical candidate is ACR-368, a selective small molecule inhibitor targeting CHK1 and CHK2, which is in a potentially registrational Phase 2 trial across various tumor types, including platinum-resistant ovarian, endometrial, and bladder cancer. The company is also developing its preclinical stage pipeline programs targeting critical nodes in the DNA damage response and cell cycle regulation pathways, such as WEE1, a protein kinase and PKMYT1, a protein serine/threonine kinase. The company was incorporated in 2018 and is based in Watertown, Massachusetts.

At a Glance

Live Snapshot
Market Cap$50.49M
EPS-2.0200
P/E Ratio-1.19
Earnings Date08/12/2026
-73.00%
Return on Invested Capital
48%
3Y+292.0%
5Y-62.0%
10Y-62.0%
-69.24%
Return on Equity
52%
3Y+279.0%
5Y-210.0%
10Y-210.0%
-60.06%
Return on Assets
47%
3Y+249.0%
5Y-75.0%
10Y-75.0%
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Acrivon Therapeutics, Inc. Common Stock Management Team

ACRV · NASDAQ
DJ

Dr. Jesper V. Olsen Ph.D.

Academic Co-Founder, Head of Phosphoproteomics & Member of Scientific Advisory Board

DE

Dr. Erick Gamelin M.D., Ph.D.

Chief Development Officer

Compensation

$480,723

Born 1958(Age 68)
DA

Dr. Adam D. Levy M.B.A., Ph.D.

Chief Financial Officer & Principal Financial Officer

Born 1966(Age 60)
MM

Ms. Mary-Alice Miller J.D.

Chief Legal Officer & Corporate Secretary

Compensation

$587,108

Born 1974(Age 52)
female
DE

Dr. Eric J. Devroe Ph.D.

Chief Operating Officer

Compensation

$774,026

Born 1979(Age 47)
DP

Dr. Peter Blume-Jensen M.D., Ph.D.

Co-Founder, Chairman of the Board, Chief Executive Officer, President & Acting Chief Scientific Officer

Compensation

$1,068,552

Born 1963(Age 63)
MK

Ms. Kristina Masson M.B.A., Ph.D.

Co-Founder, Executive Vice President of Business Operations, Site Head, Treasurer & Director

Compensation

$824,474

Born 1981(Age 45)
female
MJ

Mr. Joon Jung Ph.D.

Vice President & Head of Data Science

male
MK

Ms. Katharine Peterson CPA

Vice President of Finance & Accounting

female
MB

Mr. Bruce Close

Vice President of Quality & Compliance

male
a

Acrivon Therapeutics, Inc. Common Stock Insider Positioning

ACRV · NASDAQ

During the last 12 months, insiders have purchased $692K and sold $32K worth of ACRV shares, resulting in $659K of net buying activity.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

67.8K

114.34K

Sold

0

0.00

Net Activity

+114K

+$114K

6-9 Months

Bought

225.0K

407.25K

Sold

842

1.52K

Net Activity

+406K

+$406K

9-12 Months

Bought

141.9K

170.31K

Sold

23.4K

30.96K

Net Activity

+139K

+$139K

Top Buyers

1
MMR

Mirza Mansoor Raza

Officer: Chief Medical Officer

225.0K shares1 transactions

$407K

2
BP

Blume-Jensen Peter

Director, Officer: President And Ceo

49.0K shares1 transactions

$82K

3
SS

Shacham Sharon

Director

20.3K shares1 transactions

$24K

4
PS

Palani Santhosh

Director

20.3K shares1 transactions

$24K

5
MI

Magovcevic-Liebisch Ivana

Director

20.3K shares1 transactions

$24K

Top Sellers

1
BP

Blume-Jensen Peter

Director, Officer: President And Ceo

20.4K shares2 transactions

$27K

2
MM

Miller Mary

Officer: Chief Legal Officer

1.6K shares4 transactions

$3K

3
LAD

Levy Adam D.

Officer: Chief Financial Officer

1.2K shares1 transactions

$1K

4
DE

Devroe Eric

Officer: Chief Operating Officer

613 shares1 transactions

$852

5
GE

Gamelin Erick

Officer: Chief Development Officer

403 shares1 transactions

$560

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $659K net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

21.30:1

Exceptional buy/sell ratio. Buying dramatically outweighs selling—one of the strongest possible insider signals.

Insider Participation

Balanced

5 insider buyers and 5 sellers. Equal participation suggests mixed or neutral insider views.

Insider Activity Insight

Compelling insider conviction: The combination of strong buy/sell ratio and multiple buyers suggests insiders see attractive risk/reward. Consider this alongside fundamental analysis for confirmation.

SEC Filings

ACRV - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

April 30, 2026
June 17, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 25, 2025
June 13, 2025
2025
DEF 14A

DEF 14A 2024

N/A

April 26, 2024
June 20, 2024
2024
DEF 14A

DEF 14A 2023

N/A

May 01, 2023
June 22, 2023
2023
Showing 1 to 4 of 4 filings