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Acrivon Therapeutics, Inc. Common Stock

ACRV·NASDAQ

$1.60

-1.8%
HealthcareBiotechnology

Acrivon Therapeutics, Inc., a clinical stage biopharmaceutical company, engages in developing oncology medicines for the patients whose tumors are predicted to be sensitive to each specific medicine by utilizing its proteomics-based patient responder identification platform. The company's Acrivon Predictive Precision Proteomics, a precision medicine platform enables the creation of drug specific proprietary OncoSignature companion diagnostics that are used to identify the patients to benefit from its drug candidates. Its lead clinical candidate is ACR-368, a selective small molecule inhibitor targeting CHK1 and CHK2, which is in a potentially registrational Phase 2 trial across various tumor types, including platinum-resistant ovarian, endometrial, and bladder cancer. The company is also developing its preclinical stage pipeline programs targeting critical nodes in the DNA damage response and cell cycle regulation pathways, such as WEE1, a protein kinase and PKMYT1, a protein serine/threonine kinase. The company was incorporated in 2018 and is based in Watertown, Massachusetts.

At a Glance

Live Snapshot
Market Cap$50.49M
EPS-2.0200
P/E Ratio-1.19
Earnings Date08/12/2026
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Acrivon Therapeutics, Inc. Common Stock Street Expectations Map

ACRV · NASDAQ

Wall Street analysts project that ACRV stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 21.83, with estimates ranging from a low of 17.00 to a high of 30.00.

Lowest Target
17.00
962.50%
Consensus Target
21.83
1264.38%
Highest Target
30.00
1775.00%

The consensus 1-year price target stands at 21.83, with estimates ranging from a low of 17.00 to a high of 30.00.

Analyst Consensus Analysis

Upside Potential

+1264.4%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

59.6% spread

Mixed analyst views. Wide target range suggests differing opinions on key value drivers, growth prospects, or risk factors.

Analyst Conviction

Low

Bearish or uncertain outlook. Limited upside or poor consensus suggests challenges ahead or fundamental concerns.

Market Sentiment Insight

High risk, high reward: Substantial upside potential exists, but wide analyst disagreement signals execution risk or unclear catalysts. Thorough due diligence essential before committing capital.

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Acrivon Therapeutics, Inc. Common Stock Forward Estimates of Revenue

ACRV · NASDAQ
Latest Revenue
0.00
FY 2025
Avg Estimate
1.50M
FY 2026
Estimate Range
1.50M - 1.50M
Analyst Spread

Forward Growth Analysis

Analyst Coverage5 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

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Acrivon Therapeutics, Inc. Common Stock Forward Estimates of Net Income

ACRV · NASDAQ
Latest Net Income
-77.91M
FY 2025
Avg Estimate
-84.75M
FY 2026
Estimate Range
-86.72M - -69.71M
Analyst Spread

Forward Growth Analysis

Projected Growth-8.8%

Declining expectations indicate headwinds—investigate whether temporary or structural issues.

Analyst Coverage5 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread20%

Moderate uncertainty in forecasts—typical for companies with evolving business models.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

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Acrivon Therapeutics, Inc. Common Stock Forward Estimates of EPS

ACRV · NASDAQ
Latest EPS
-2.02
FY 2025
Avg Estimate
$-2.07
FY 2026
Estimate Range
$-2.25 - $-1.81
Analyst Spread

Forward Growth Analysis

Projected Growth-2.4%

Declining expectations indicate headwinds—investigate whether temporary or structural issues.

Analyst Coverage6 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread21%

Moderate uncertainty in forecasts—typical for companies with evolving business models.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

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Acrivon Therapeutics, Inc. Common Stock Forward Estimates of EBIT

ACRV · NASDAQ
Latest EBIT
-84.11M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage5 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

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Acrivon Therapeutics, Inc. Common Stock Forward Estimates of EBITDA

ACRV · NASDAQ
Latest EBITDA
-82.76M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage5 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

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Acrivon Therapeutics, Inc. Common Stock Forward Estimates of SG&A Expense

ACRV · NASDAQ
Latest SG&A Expense
24.12M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth-100.0%

Significant contraction projected—major business challenges or industry disruption likely.

Analyst Coverage5 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

OutlookCautious

Analyst skepticism evident—carefully evaluate risks before investment decisions.

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Acrivon Therapeutics, Inc. Common Stock Insider Positioning

ACRV · NASDAQ

During the last 12 months, insiders have purchased $692K and sold $32K worth of ACRV shares, resulting in $659K of net buying activity.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

67.8K

114.34K

Sold

0

0.00

Net Activity

+114K

+$114K

6-9 Months

Bought

225.0K

407.25K

Sold

842

1.52K

Net Activity

+406K

+$406K

9-12 Months

Bought

141.9K

170.31K

Sold

23.4K

30.96K

Net Activity

+139K

+$139K

Top Buyers

1
MMR

Mirza Mansoor Raza

Officer: Chief Medical Officer

225.0K shares1 transactions

$407K

2
BP

Blume-Jensen Peter

Director, Officer: President And Ceo

49.0K shares1 transactions

$82K

3
SS

Shacham Sharon

Director

20.3K shares1 transactions

$24K

4
PS

Palani Santhosh

Director

20.3K shares1 transactions

$24K

5
MI

Magovcevic-Liebisch Ivana

Director

20.3K shares1 transactions

$24K

Top Sellers

1
BP

Blume-Jensen Peter

Director, Officer: President And Ceo

20.4K shares2 transactions

$27K

2
MM

Miller Mary

Officer: Chief Legal Officer

1.6K shares4 transactions

$3K

3
LAD

Levy Adam D.

Officer: Chief Financial Officer

1.2K shares1 transactions

$1K

4
DE

Devroe Eric

Officer: Chief Operating Officer

613 shares1 transactions

$852

5
GE

Gamelin Erick

Officer: Chief Development Officer

403 shares1 transactions

$560

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $659K net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

21.30:1

Exceptional buy/sell ratio. Buying dramatically outweighs selling—one of the strongest possible insider signals.

Insider Participation

Balanced

5 insider buyers and 5 sellers. Equal participation suggests mixed or neutral insider views.

Insider Activity Insight

Compelling insider conviction: The combination of strong buy/sell ratio and multiple buyers suggests insiders see attractive risk/reward. Consider this alongside fundamental analysis for confirmation.