Xenon Pharmaceuticals Inc.

Xenon Pharmaceuticals Inc.

Healthcare

NASDAQ:XENE · NASDAQ Global Market

Market Cap $4.12B Beta 0.63 P/E (TTM) -11.9
$52.10 -0.17%

-$0.09 today

52W Low $30.00High $63.95

Vol 0.69M · Avg 1.22M

EPS (TTM)-$4.39
Biotechnology

Management

Put operating results in leadership context

Review returns on capital, executive background, insider transactions, and growth quality to judge whether management is compounding value well.

Return Metrics

ROE, ROIC & ROA over time

Management

ROE

-59.5%

avg -35.0%

ROIC

-39.6%

avg -31.8%

ROA

-35.2%

avg -28.3%

Analysis

ROA is currently the strongest return metric at -35.2% versus its period average of -28.3%. 0 of 3 return metrics are above their quality threshold, which helps indicate how efficiently the company turns capital and assets into profit.

Management

Key executives, compensation & ownership

Management
NameTitleCompensationTenureAgeShares OwnedOwnership %

Ian C. Mortimer

President, Chief Executive Officer & Director$1.38M50$19,923.000.03%

Christopher John Kenney

Chief Medical Officer$848,652.0055$7,069.00<0.01%

Andrea DiFabio

Chief Legal Officer & Corporate Secretary$766,152.0058$7,301.00<0.01%

Darren S. Cline

Chief Commercial Officer$619,768.0062$40,000.000.05%

Robin Sherrington

Executive Vice President of Strategy & Innovation$587,028.0065$65,000.000.08%

Thomas Patrick Kelly

Chief Financial Officer$515,697.0055$10,507.000.01%

James R. Empfield

Executive Vice President of Drug Discovery$323,428.0065$65,000.000.08%

Shelley McCloskey

Executive Vice President of Human Resources66

Colleen Alabiso

Senior Vice President of Corporate Affairs

Matthew D. Ronsheim

Chief Operating Officer54$1,593.00<0.01%

Gilbert

Senior Director

Shelley McClCoskey

Executive Vice President of Human Resources66

Insider Trading

SEC Form 4 transactions — last 12 months

Management

Buys

0

$0.00

Sells

24

$21.91M

Net Sentiment

$21.91M

Net selling

Most Active

MORTIMER IAN

18 transactions

DateInsiderTypeSharesPriceValue
Jun 5, 2026

PATOU GARY

Direct

Sell1.3K$53.14$70,251.08
Jun 5, 2026

Cannon Gillian

Direct

Sell1.2K$53.14$63,236.60
Mar 13, 2026

DiFabio Andrea

Direct

Sell1.3K$55.23$74,111.95
Mar 13, 2026

KENNEY CHRISTOPHER JOHN

Direct

Sell1.4K$55.23$77,867.25
Mar 13, 2026

MORTIMER IAN

Direct

Sell7.3K$55.23$403,584.30
Mar 10, 2026

DiFabio Andrea

Direct

Sell2.6K$60.11$156,701.56
Mar 10, 2026

MORTIMER IAN

Direct

Sell11.3K$60.11$677,357.05
Mar 10, 2026

KENNEY CHRISTOPHER JOHN

Direct

Sell2.8K$60.11$166,559.27
Mar 9, 2026

MORTIMER IAN

Direct

Sell12.5K$59.50$742,500.50
Mar 9, 2026

MORTIMER IAN

Direct

Sell43.3K$59.26$2,568,802.48

1–10 of 24

Analysis

Insiders reported 0 buys worth $0.00 and 24 sells worth $21.91M over the last 12 months. That adds up to net selling of $21.91M. MORTIMER IAN was the most active insider with 18 transactions.

Growth Analysis

Historical CAGR & forward analyst estimates

Metric 10yr5yr3yr Fwd Est.
EPSN/AN/AN/A
N/A5 analysts
RevenueN/AN/A+2.9%
+33.5% (15yr)13 analysts
Net IncomeN/AN/AN/A
N/A13 analysts
EBITN/AN/AN/A
N/A13 analysts

Analysis

Recent growth has been strongest in Revenue at +2.9% over three years. Forward estimates point to Revenue at +33.5% (15yr), giving you a quick check on whether expectations are accelerating or cooling.

Who manages XENE?

Xenon Pharmaceuticals Inc. (XENE) lists 12 active executives. The top listed executive is Ian C. Mortimer, President, Chief Executive Officer & Director.

Are XENE insiders buying or selling?

Recent insider activity shows net buying of $76.58M.

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