Stoke Therapeutics, Inc.

Stoke Therapeutics, Inc.

Healthcare

NASDAQ:STOK · NASDAQ Global Select

Market Cap $1.83B Beta 1.19 P/E (TTM) -11.1
$29.82 +1.57%

+$0.46 today

52W Low $11.17High $40.22

Vol 0.46M · Avg 0.65M

EPS (TTM)-$2.69
Biotechnology

Management

Put operating results in leadership context

Review returns on capital, executive background, insider transactions, and growth quality to judge whether management is compounding value well.

Return Metrics

ROE, ROIC & ROA over time

Management

ROE

-2.0%

avg 20.6%

ROIC

-5.7%

avg -62.2%

ROA

-1.6%

avg -47.4%

Analysis

ROA is currently the strongest return metric at -1.6% versus its period average of -47.4%. 0 of 3 return metrics are above their quality threshold, which helps indicate how efficiently the company turns capital and assets into profit.

Management

Key executives, compensation & ownership

Management
NameTitleCompensationTenureAgeShares OwnedOwnership %

Ian F. Smith

Chief Executive Officer & Director$1.41M60$17,786.000.03%

Jason Hoitt

Chief Patient Officer$815,418.0048$10,445.000.02%

Thomas Edward Leggett

Chief Financial Officer$804,024.0049$17,786.000.03%

Edward Kaye

Advisor & Director$736,384.0077$17,786.000.03%

Barry S. Ticho FACC

Chief Medical Officer$726,501.0065$34,826.000.06%

Adrian R. Krainer

Co-Founder & Independent Director$45,000.0067$17,786.000.03%

Doug Snow

Director of Communications & Investor Relations

Jonathan Allan

Corporate Secretary & General Counsel36$19,543.000.03%

Dawn Kalmar

Chief of Corporate Affairs & Strategic Partnerships49

Isabel Aznarez

Co-Founder, Head of Research & Senior Vice President53

Sara Den Besten

Chief People Officer

Susan Willson

Vice President of Corporate Communications

Insider Trading

SEC Form 4 transactions — last 12 months

Management

Buys

0

$0.00

Sells

85

$12.20M

Net Sentiment

$12.20M

Net selling

Most Active

Ticho Barry

26 transactions

DateInsiderTypeSharesPriceValue
Jun 1, 2026

Ticho Barry

Direct

Sell1.8K$30.58$54,891.10
May 1, 2026

Ticho Barry

Direct

Sell2.2K$32.79$73,547.97
Apr 1, 2026

Ticho Barry

Direct

Sell1.8K$32.66$60,029.08
Mar 20, 2026

Allan Jonathan

Direct

Sell8.7K$33.64$292,358.90
Mar 20, 2026

Allan Jonathan

Direct

Sell601$34.41$20,679.15
Mar 19, 2026

Ticho Barry

Direct

Sell1.5K$29.99$43,815.39
Mar 18, 2026

Allan Jonathan

Direct

Sell72$32.85$2,365.20
Mar 18, 2026

Ticho Barry

Direct

Sell6.1K$31.28$190,831.18
Mar 18, 2026

Ticho Barry

Direct

Sell483$31.79$15,353.99
Mar 18, 2026

Ticho Barry

Direct

Sell103$32.85$3,383.55

1–10 of 85

Analysis

Insiders reported 0 buys worth $0.00 and 85 sells worth $12.20M over the last 12 months. That adds up to net selling of $12.20M. Ticho Barry was the most active insider with 26 transactions.

Growth Analysis

Historical CAGR & forward analyst estimates

Metric 10yr5yr3yr Fwd Est.
EPSN/AN/AN/A
N/A5 analysts
RevenueN/AN/AN/A
N/A7 analysts
Net IncomeN/AN/AN/A
N/A7 analysts
EBITN/AN/AN/A
N/A7 analysts

Analysis

Analysis will appear once historical growth or forward estimates are available for this company.

Who manages STOK?

Stoke Therapeutics, Inc. (STOK) lists 12 active executives. The top listed executive is Doug Snow, Director of Communications & Investor Relations.

Are STOK insiders buying or selling?

Recent insider activity shows net selling of $480,350.21.

Explore More

Continue the stock analysis

Jump to another research area for this company.