Silence Therapeutics plc

Silence Therapeutics plc

Healthcare

NASDAQ:SLN · NASDAQ Global Market

Market Cap $315.52M Beta 1.44 P/E (TTM) -3.7
$6.69 +0.15%

+$0.01 today

52W Low $4.19High $8.40

Vol 0.24M · Avg 0.31M

EPS (TTM)-$1.80
Biotechnology

Management

Put operating results in leadership context

Review returns on capital, executive background, insider transactions, and growth quality to judge whether management is compounding value well.

Return Metrics

ROE, ROIC & ROA over time

Management

ROE

-142.2%

avg -142.2%

ROIC

-76.1%

avg -42.6%

ROA

-67.4%

avg -33.4%

Analysis

ROA is currently the strongest return metric at -67.4% versus its period average of -33.4%. 0 of 3 return metrics are above their quality threshold, which helps indicate how efficiently the company turns capital and assets into profit.

Management

Key executives, compensation & ownership

Management
NameTitleCompensationTenureAgeShares OwnedOwnership %

Rhonda L. Hellums

Executive VP, CFO, Secretary & Executive Director$512,932.0055$375,000.000.79%

Steven J. Romano

Executive Vice President and Chief Research & Development Officer$496,667.0067$300,000.000.64%

Iain Gladstone Ross

Interim CEO & Chairman of the Board$481,912.0072$900,000.001.91%

Marie Wikstrom Lindholm

Chief Scientific Officer

Curtis Rambaran

Chief Medical Officer

Jaimin Shah

SVP & General Counsel

Gabriel

Chief Technical Operations Officer

Gem Gokmen Hopkins

Head of IR & Corporation Communications

Gianine Esposito

Chief Human Resources Officer

Insider Trading

SEC Form 4 transactions — last 12 months

Management

Buys

23

$3.01M

Sells

0

$0.00

Net Sentiment

+$3.01M

Net buying

Most Active

Griffiths Richard Ian

23 transactions

DateInsiderTypeSharesPriceValue
Oct 27, 2025

Griffiths Richard Ian

Indirect

Buy2.0K$7.75$15,500.00
Oct 27, 2025

Griffiths Richard Ian

Indirect

Buy2.0K$7.75$15,500.00
Aug 3, 2025

Griffiths Richard Ian

Indirect

Buy20.0K$5.45$109,000.00
Aug 3, 2025

Griffiths Richard Ian

Indirect

Buy20.0K$5.45$109,000.00
Aug 1, 2025

Griffiths Richard Ian

Indirect

Buy4.0K$6.14$24,768.76
Jul 31, 2025

Griffiths Richard Ian

Indirect

Buy14.3K$6.18$88,633.56
Jul 30, 2025

Griffiths Richard Ian

Indirect

Buy8.9K$6.14$54,787.22
Jul 29, 2025

Griffiths Richard Ian

Indirect

Buy14.6K$6.20$90,265.80
Jul 22, 2025

Griffiths Richard Ian

Indirect

Buy2.9K$6.09$17,721.90
Jul 21, 2025

Griffiths Richard Ian

Indirect

Buy22.4K$6.04$135,507.40

1–10 of 23

Analysis

Insiders reported 23 buys worth $3.01M and 0 sells worth $0.00 over the last 12 months. That adds up to net buying of $3.01M. Griffiths Richard Ian was the most active insider with 23 transactions.

Growth Analysis

Historical CAGR & forward analyst estimates

Metric 10yr5yr3yr Fwd Est.
EPSN/AN/AN/A
N/A1 analysts
RevenueN/AN/AN/A
N/A3 analysts
Net IncomeN/AN/AN/A
N/A3 analysts
EBITN/AN/AN/A
N/A3 analysts

Analysis

Analysis will appear once historical growth or forward estimates are available for this company.

Who manages SLN?

Silence Therapeutics plc (SLN) lists 9 active executives. The top listed executive is Steven J. Romano, Executive Vice President and Chief Research & Development Officer.

Are SLN insiders buying or selling?

Recent insider activity shows net buying of $20.17M.

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