Rhythm Pharmaceuticals, Inc.

Rhythm Pharmaceuticals, Inc.

Healthcare

NASDAQ:RYTM · NASDAQ Global Market

Market Cap $6.06B Beta 1.92 P/E (TTM) -29.6
$88.38 +0.82%

+$0.72 today

52W Low $60.70High $122.20

Vol 0.55M · Avg 0.80M

EPS (TTM)-$2.98
Biotechnology

Management

Put operating results in leadership context

Review returns on capital, executive background, insider transactions, and growth quality to judge whether management is compounding value well.

Return Metrics

ROE, ROIC & ROA over time

Management

ROE

-141.3%

avg -97.3%

ROIC

-50.1%

avg -80.3%

ROA

-40.8%

avg -57.7%

Analysis

ROA is currently the strongest return metric at -40.8% versus its period average of -57.7%. 0 of 3 return metrics are above their quality threshold, which helps indicate how efficiently the company turns capital and assets into profit.

Management

Key executives, compensation & ownership

Management
NameTitleCompensationTenureAgeShares OwnedOwnership %

David Meeker

Chairman, President & Chief Executive Officer$1.58M72$107,850.000.16%

Yann Mazabraud

Executive Vice President & Head of International$972,148.0053$10,375.000.02%

Hunter C. Smith

Chief Financial Officer & Treasurer$892,477.0057$119,611.000.17%

Jennifer Lee

Executive Vice President & Head of North America$838,635.0051$32,500.000.05%

Alastair Garfield

Chief Scientific Officer$806,385.0046$25,000.000.04%

Joseph Shulman

Chief Technical Officer$734,854.0051$22,500.000.03%

Pamela J. Cramer

Chief Human Resources Officer52$17,500.000.03%

Sarah Ryan

Vice President of Sales & Marketing

Jim Flaherty

Senior Vice President & General Counsel

Elisabeth Cronert-Bendell

Senior Vice President & Head of Strategy

Christopher German

Corporate Controller & Principal Accounting Officer54$2,701.00<0.01%

David Connolly

Head of Investor Relations & Corporate Communications$107,850.000.16%

Insider Trading

SEC Form 4 transactions — last 12 months

Management

Buys

0

$0.00

Sells

53

$20.33M

Net Sentiment

$20.33M

Net selling

Most Active

Smith Hunter C

28 transactions

DateInsiderTypeSharesPriceValue
May 15, 2026

German Christopher Paul

Direct

Sell4.6K$92.21$428,131.03
Mar 4, 2026

German Christopher Paul

Direct

Sell5.6K$89.56$502,789.84
Feb 19, 2026

Smith Hunter C

Direct

Sell1.3K$100.27$131,152.90
Feb 19, 2026

Smith Hunter C

Direct

Sell1.7K$100.92$170,754.78
Feb 19, 2026

Smith Hunter C

Direct

Sell800$102.10$81,676.08
Feb 19, 2026

Smith Hunter C

Direct

Sell585$103.28$60,420.44
Feb 17, 2026

Smith Hunter C

Direct

Sell200$103.84$20,768.00
Feb 17, 2026

Smith Hunter C

Direct

Sell1.2K$99.42$119,298.00
Feb 17, 2026

Smith Hunter C

Direct

Sell200$100.52$20,104.00
Feb 17, 2026

Smith Hunter C

Direct

Sell900$101.70$91,530.00

1–10 of 53

Analysis

Insiders reported 0 buys worth $0.00 and 53 sells worth $20.33M over the last 12 months. That adds up to net selling of $20.33M. Smith Hunter C was the most active insider with 28 transactions.

Growth Analysis

Historical CAGR & forward analyst estimates

Metric 10yr5yr3yr Fwd Est.
EPSN/AN/AN/A
N/A3 analysts
RevenueN/AN/AN/A
N/A5 analysts
Net IncomeN/AN/AN/A
N/A5 analysts
EBITN/AN/AN/A
N/A5 analysts

Analysis

Analysis will appear once historical growth or forward estimates are available for this company.

Who manages RYTM?

Rhythm Pharmaceuticals, Inc. (RYTM) lists 12 active executives. The top listed executive is Hunter C. Smith, Chief Financial Officer & Treasurer.

Are RYTM insiders buying or selling?

Recent insider activity shows net buying of $3.73M.

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