Ultragenyx Pharmaceutical Inc.

Ultragenyx Pharmaceutical Inc.

Healthcare

NASDAQ:RARE · NASDAQ Global Select

Market Cap $2.40B Beta 0.38 P/E (TTM) -4.0
$24.35 +1.54%

+$0.37 today

52W Low $18.29High $42.37

Vol 1.85M · Avg 1.81M

EPS (TTM)-$6.06
Biotechnology

Management

Put operating results in leadership context

Review returns on capital, executive background, insider transactions, and growth quality to judge whether management is compounding value well.

Return Metrics

ROE, ROIC & ROA over time

Management

ROE

718.8%

avg -22.1%

ROIC

-43.5%

avg -44.3%

ROA

-37.5%

avg -36.2%

Analysis

ROE is currently the strongest return metric at 718.8% versus its period average of -22.1%. 1 of 3 return metrics are above their quality threshold, which helps indicate how efficiently the company turns capital and assets into profit.

Management

Key executives, compensation & ownership

Management
NameTitleCompensationTenureAgeShares OwnedOwnership %

Emil D. Kakkis

Founder, President, Chief Executive Officer & Director$1.19M66$23,095.000.02%

Erik Harris

Executive Vice President & Chief Commercial Officer$925,255.0056$118,410.000.12%

John Richard Pinion

Chief Quality Operations Officer & Executive Vice President of Translational Sciences$923,934.0060$133,142.000.14%

Eric Crombez

Chief Medical Officer & Executive Vice President$882,356.0053$111,189.000.11%

Howard Horn

Executive Vice President of Corporate Strategy & Chief Financial Officer$846,010.0047$105,689.000.11%

Karah Herdman Parschauer

Chief Legal Officer & Executive Vice President of Corporate Affairs$819,872.0048$95,715.000.10%

Dennis Karl Huang

Chief Technical Operations Officer and Executive Vice President of Gene Therapy Operations$331,330.0061$79,936.000.08%

Ernie W. Meyer

Chief Human Resources Officer & Executive Vice President61

Theodore A. Huizenga

Senior Vice President, Corporate Controller & Principal Accounting Officer55$68,911.000.07%

Vimal Srivastava

Senior Vice President of Business Development & Alliance Management61

Insider Trading

SEC Form 4 transactions — last 12 months

Management

Buys

0

$0.00

Sells

25

$3.69M

Net Sentiment

$3.69M

Net selling

Most Active

Horn Howard

10 transactions

DateInsiderTypeSharesPriceValue
Jun 1, 2026

Horn Howard

Direct

Sell4.7K$23.77$110,601.81
May 18, 2026

SULIMAN SHEHNAAZ

Direct

Sell5.7K$25.12$144,188.80
May 5, 2026

Crombez Eric

Direct

Sell344$24.96$8,586.24
May 1, 2026

Horn Howard

Direct

Sell4.7K$24.90$116,606.70
Apr 1, 2026

Horn Howard

Direct

Sell4.7K$20.97$98,202.51
Mar 10, 2026

Parschauer Karah Herdman

Direct

Sell3.5K$22.67$79,526.36
Mar 6, 2026

Parschauer Karah Herdman

Direct

Sell6.0K$21.40$128,785.20
Mar 3, 2026

Horn Howard

Direct

Sell1.6K$22.40$36,624.00
Mar 2, 2026

Horn Howard

Direct

Sell3.1K$22.54$70,302.26
Mar 2, 2026

Pinion John Richard

Direct

Sell10.0K$22.80$228,661.20

1–10 of 25

Analysis

Insiders reported 0 buys worth $0.00 and 25 sells worth $3.69M over the last 12 months. That adds up to net selling of $3.69M. Horn Howard was the most active insider with 10 transactions.

Growth Analysis

Historical CAGR & forward analyst estimates

Metric 10yr5yr3yr Fwd Est.
EPSN/AN/AN/A
N/A5 analysts
RevenueN/AN/AN/A
N/A6 analysts
Net IncomeN/AN/AN/A
N/A6 analysts
EBITN/AN/AN/A
N/A6 analysts

Analysis

Analysis will appear once historical growth or forward estimates are available for this company.

Who manages RARE?

Ultragenyx Pharmaceutical Inc. (RARE) lists 10 active executives. The top listed executive is Emil D. Kakkis, Founder, President, Chief Executive Officer & Director.

Are RARE insiders buying or selling?

Recent insider activity shows net buying of $29.74M.

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