Q32 Bio Inc.

Q32 Bio Inc.

Healthcare

NASDAQ:QTTB · NASDAQ Global Market

Market Cap $162.26M Beta -0.23 P/E (TTM) 5.4
$12.64 -0.47%

-$0.06 today

52W Low $1.35High $14.85

Vol 0.33M · Avg 0.74M

EPS (TTM)$2.36
Biotechnology

Management

Put operating results in leadership context

Review returns on capital, executive background, insider transactions, and growth quality to judge whether management is compounding value well.

Return Metrics

ROE, ROIC & ROA over time

Management

ROE

71.0%

avg -109.3%

ROIC

29.5%

avg -61.6%

ROA

48.3%

avg -41.4%

Analysis

ROE is currently the strongest return metric at 71.0% versus its period average of -109.3%. 3 of 3 return metrics are above their quality threshold, which helps indicate how efficiently the company turns capital and assets into profit.

Management

Key executives, compensation & ownership

Management
NameTitleCompensationTenureAgeShares OwnedOwnership %

Jodie Pope Morrison

Chief Executive Officer & Director$1.00M50$89,104.000.70%

Lee H. Kalowski

Chief Financial Officer & President$792,770.0045$35,943.000.28%

Shelia Violette

Co-founder, Chief Scientific Officer & President of Research$641,884.0065$55,569.000.43%

David Appugliese

Senior Vice President & Head of People$16,363.000.13%

Maria Marzilli

Chief Business Officer

Insider Trading

SEC Form 4 transactions — last 12 months

Management

Buys

4

$30.00M

Sells

8

$216,604.72

Net Sentiment

+$29.78M

Net buying

Most Active

Kalowski Lee

3 transactions

DateInsiderTypeSharesPriceValue
May 28, 2026

Xu Diyong

Indirect

Buy1.25M$8.00$10,000,000.00
May 28, 2026

Xu Diyong

Indirect

Buy625.0K$8.00$5,000,000.00
May 28, 2026

ORBIMED ADVISORS LLC

Indirect

Buy1.25M$8.00$10,000,000.00
May 28, 2026

ORBIMED ADVISORS LLC

Indirect

Buy625.0K$8.00$5,000,000.00
Feb 25, 2026

Violette Shelia M.

Direct

Sell2.8K$4.51$12,708.04
Feb 25, 2026

Kalowski Lee

Direct

Sell4.0K$4.51$18,035.03
Feb 25, 2026

Morrison Jodie Pope

Direct

Sell9.9K$4.51$44,674.50
Dec 2, 2025

Morrison Jodie Pope

Direct

Sell22.5K$3.46$77,870.76
Dec 2, 2025

Kalowski Lee

Direct

Sell9.1K$3.46$31,395.47
Aug 26, 2025

Morrison Jodie Pope

Direct

Sell10.5K$1.80$18,899.69

1–10 of 12

Analysis

Insiders reported 4 buys worth $30.00M and 8 sells worth $216,604.72 over the last 12 months. That adds up to net buying of $29.78M. Kalowski Lee was the most active insider with 3 transactions.

Growth Analysis

Historical CAGR & forward analyst estimates

Metric 10yr5yr3yr Fwd Est.
EPSN/AN/AN/A
N/A1 analysts
RevenueN/AN/AN/A
+49.9% (10yr)2 analysts
Net IncomeN/AN/AN/A
N/A2 analysts
EBITN/AN/AN/A
N/A2 analysts

Analysis

Forward estimates point to Revenue at +49.9% (10yr), giving you a quick read on expected growth from here.

Who manages QTTB?

Q32 Bio Inc. (QTTB) lists 5 active executives. The top listed executive is Shelia Violette, Co-founder, Chief Scientific Officer & President of Research.

Are QTTB insiders buying or selling?

Recent insider activity shows net buying of $30.02M.

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