Orchestra BioMed Holdings, Inc.

Orchestra BioMed Holdings, Inc.

Healthcare

NASDAQ:OBIO · NASDAQ Global Market

Market Cap $240.72M Beta 0.50 P/E (TTM) -2.9
$4.10 +0.74%

+$0.03 today

52W Low $2.20High $5.42

Vol 0.54M · Avg 0.21M

EPS (TTM)-$1.42
Biotechnology

Management

Put operating results in leadership context

Review returns on capital, executive background, insider transactions, and growth quality to judge whether management is compounding value well.

Return Metrics

ROE, ROIC & ROA over time

Management

ROE

-83.2%

avg -54.7%

ROIC

-52.4%

avg -165.4%

ROA

-45.9%

avg -73.2%

Analysis

ROA is currently the strongest return metric at -45.9% versus its period average of -73.2%. 0 of 3 return metrics are above their quality threshold, which helps indicate how efficiently the company turns capital and assets into profit.

Management

Key executives, compensation & ownership

Management
NameTitleCompensationTenureAgeShares OwnedOwnership %

David Hochman

Founder, Chairman of the Board of Directors & Chief Executive Officer$1.18M51$436,199.000.73%

Darren R. Sherman

Founder, President, Chief Operating Officer & Director$1.04M55$1.18M1.98%

Andrew Lawrence Taylor

Chief Financial Officer$766,677.0055$593,065.000.99%

Yuval Hay Mika D.Sc

GM & Chief Technology Officer of Bioelectronic Therapies67$158,905.000.27%

Bob Laughner

Senior Vice President of Regulatory & Quality

William Reed Little

Executive Vice President of Corporate Development & Strategy55$307,859.000.51%

Avraham Matityahu Fischer

Senior Vice President of Medical Affairs & Innovation70

Hans-Peter Stoll

Senior Vice President & Medical Director

Juan Lorenzo

Senior Vice President of Product Development

Lisa Daniels

Vice President of Human Resources

Insider Trading

SEC Form 4 transactions — last 12 months

Management

Buys

16

$2.25M

Sells

3

$66,365.31

Net Sentiment

+$2.18M

Net buying

Most Active

Hochman David P

6 transactions

DateInsiderTypeSharesPriceValue
Jun 1, 2026

Hochman David P

Direct

Buy5.0K$3.83$19,150.00
Jun 1, 2026

Sherman Darren

Direct

Sell15.0K$3.87$58,050.00
May 18, 2026

Aryeh Jason

Direct

Buy665$3.75$2,493.75
May 15, 2026

Aryeh Jason

Direct

Buy9.0K$3.90$34,986.90
May 15, 2026

Hochman David P

Direct

Buy5.0K$3.77$18,850.00
May 14, 2026

Fain Eric S

Indirect

Buy20.0K$4.13$82,600.00
Apr 27, 2026

RTW INVESTMENTS, LP

Indirect

Sell32$4.13$132.16
Mar 13, 2026

Hochman David P

Direct

Buy10.0K$4.29$42,900.00
Nov 14, 2025

Hochman David P

Direct

Buy5.0K$4.07$20,350.00
Sep 19, 2025

Aryeh Jason

Direct

Buy1.0K$2.45$2,450.00

1–10 of 19

Analysis

Insiders reported 16 buys worth $2.25M and 3 sells worth $66,365.31 over the last 12 months. That adds up to net buying of $2.18M. Hochman David P was the most active insider with 6 transactions.

Growth Analysis

Historical CAGR & forward analyst estimates

Metric 10yr5yr3yr Fwd Est.
EPSN/AN/AN/A
N/A1 analysts
RevenueN/AN/AN/A
+86.6% (6yr)2 analysts
Net IncomeN/AN/AN/A
N/A2 analysts
EBITN/AN/AN/A
N/A2 analysts

Analysis

Forward estimates point to Revenue at +86.6% (6yr), giving you a quick read on expected growth from here.

Who manages OBIO?

Orchestra BioMed Holdings, Inc. (OBIO) lists 10 active executives. The top listed executive is Yuval Hay Mika D.Sc, GM & Chief Technology Officer of Bioelectronic Therapies.

Are OBIO insiders buying or selling?

Recent insider activity shows net buying of $23.53M.

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