Lexicon Pharmaceuticals, Inc.

Lexicon Pharmaceuticals, Inc.

Healthcare

NASDAQ:LXRX · NASDAQ Global Select

Market Cap $839.53M Beta 1.07 P/E (TTM) -29.5
$1.92 +1.59%

+$0.03 today

52W Low $0.64High $2.53

Vol 2.99M · Avg 2.44M

EPS (TTM)-$0.07
Biotechnology

Management

Put operating results in leadership context

Review returns on capital, executive background, insider transactions, and growth quality to judge whether management is compounding value well.

Return Metrics

ROE, ROIC & ROA over time

Management

ROE

-46.8%

avg -72.4%

ROIC

-28.7%

avg -40.5%

ROA

-27.2%

avg -35.3%

Analysis

ROA is currently the strongest return metric at -27.2% versus its period average of -35.3%. 0 of 3 return metrics are above their quality threshold, which helps indicate how efficiently the company turns capital and assets into profit.

Management

Key executives, compensation & ownership

Management
NameTitleCompensationTenureAgeShares OwnedOwnership %

Michael Exton

Chief Executive Officer & Director$1.15M56$1.01M0.23%

Craig Granowitz

Senior Vice President & Chief Medical Officer$789,535.0061$432,528.000.10%

Brian T. Crum

Senior Vice President, General Counsel & Secretary$687,366.0053$428,802.000.10%

Scott Coiante

Senior Vice President & Chief Financial Officer$646,287.0059$320,473.000.07%

Wendy E. McDermott

Senior Vice President of Human Resources$580,446.0055$126,122.000.03%

Kristen L. Alexander

Vice President of Finance & Accounting$379,807.0058$94,230.000.02%

Suma Gopinathan

Senior Vice President of Discovery53$174,470.000.04%

Lisa DeFrancesco

Senior Vice President of Investor Relations & Corporate Communications46$256,380.000.06%

Rachel Yap Martens

Senior VP of Partnerships & Corporate Strategy42$134,180.000.03%

Insider Trading

SEC Form 4 transactions — last 12 months

Management

Buys

8

$2.72M

Sells

0

$0.00

Net Sentiment

+$2.72M

Net buying

Most Active

DEBBANE RAYMOND

7 transactions

DateInsiderTypeSharesPriceValue
Feb 25, 2026

DEBBANE RAYMOND

Direct

Buy2.0K$1.49$2,980.00
Feb 23, 2026

DEBBANE RAYMOND

Direct

Buy100.0K$1.47$147,000.00
Feb 20, 2026

DEBBANE RAYMOND

Direct

Buy100.0K$1.48$147,790.00
Feb 19, 2026

DEBBANE RAYMOND

Direct

Buy50.0K$1.44$71,965.00
Feb 18, 2026

DEBBANE RAYMOND

Direct

Buy133.7K$1.32$176,468.16
Feb 17, 2026

DEBBANE RAYMOND

Direct

Buy76.9K$1.31$100,544.33
Feb 13, 2026

DEBBANE RAYMOND

Direct

Buy58.0K$1.31$75,876.55
Feb 2, 2026

Invus Global Management, LLC

Indirect

Buy1.54M$1.30$2,000,000.60

Analysis

Insiders reported 8 buys worth $2.72M and 0 sells worth $0.00 over the last 12 months. That adds up to net buying of $2.72M. DEBBANE RAYMOND was the most active insider with 7 transactions.

Growth Analysis

Historical CAGR & forward analyst estimates

Metric 10yr5yr3yr Fwd Est.
EPSN/AN/AN/A
N/A2 analysts
RevenueN/AN/A+392.4%
-1.2% (15yr)2 analysts
Net IncomeN/AN/AN/A
N/A2 analysts
EBITN/AN/AN/A
N/A2 analysts

Analysis

Recent growth has been strongest in Revenue at +392.4% over three years. Forward estimates point to Revenue at -1.2% (15yr), giving you a quick check on whether expectations are accelerating or cooling.

Who manages LXRX?

Lexicon Pharmaceuticals, Inc. (LXRX) lists 9 active executives. The top listed executive is Brian T. Crum, Senior Vice President, General Counsel & Secretary.

Are LXRX insiders buying or selling?

Recent insider activity shows net buying of $69.00M.

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