Design Therapeutics, Inc.

Design Therapeutics, Inc.

Healthcare

NASDAQ:DSGN · NASDAQ Global Select

Market Cap $665.79M Beta 1.66 P/E (TTM) -9.7
$10.97 +4.18%

+$0.44 today

52W Low $3.33High $17.25

Vol 0.46M · Avg 0.73M

EPS (TTM)-$1.13
Biotechnology

Management

Put operating results in leadership context

Review returns on capital, executive background, insider transactions, and growth quality to judge whether management is compounding value well.

Return Metrics

ROE, ROIC & ROA over time

Management

ROE

-32.8%

avg 3.3%

ROIC

-37.3%

avg -11.5%

ROA

-30.9%

avg -342.6%

Analysis

ROA is currently the strongest return metric at -30.9% versus its period average of -342.6%. 0 of 3 return metrics are above their quality threshold, which helps indicate how efficiently the company turns capital and assets into profit.

Management

Key executives, compensation & ownership

Management
NameTitleCompensationTenureAgeShares OwnedOwnership %

Pratik Shah

Co-Founder, President, Chief Executive Officer, Principal Financial Officer & Executive Chairperson$790,000.0056$750,000.001.20%

Sean Jeffries

Chief Operating Officer$698,000.0046$375,000.000.60%

Chris Storgard

Chief Medical Officer$633,760.0060$250,000.000.40%

Aseem Z. Ansari

Co-Founder & Scientific Advisor$100,000.000.16%

Julie D. Burgess

Chief Accounting Officer$30,000.000.05%

Doane Chilcoat

Chief Technology Officer

Jim Kerr

Chief of Manufacturing & Product Development

Tadimeti S. Rao

Chief Scientific Officer

Mustapha Parekh

General Counsel

Chengzhi Zhang

Chief Chemist

Insider Trading

SEC Form 4 transactions — last 12 months

Management

Buys

0

$0.00

Sells

2

$2.95M

Net Sentiment

$2.95M

Net selling

Most Active

William Arsani

2 transactions

DateInsiderTypeSharesPriceValue
Aug 13, 2025

William Arsani

Indirect

Sell345.0K$5.25$1,811,250.00
Aug 13, 2025

William Arsani

Indirect

Sell217.6K$5.25$1,142,541.75

Analysis

Insiders reported 0 buys worth $0.00 and 2 sells worth $2.95M over the last 12 months. That adds up to net selling of $2.95M. William Arsani was the most active insider with 2 transactions.

Growth Analysis

Historical CAGR & forward analyst estimates

Metric 10yr5yr3yr Fwd Est.
EPSN/AN/AN/A
N/A1 analysts
RevenueN/AN/AN/A
N/A3 analysts
Net IncomeN/AN/AN/A
N/A3 analysts
EBITN/AN/AN/A
N/A3 analysts

Analysis

Analysis will appear once historical growth or forward estimates are available for this company.

Who manages DSGN?

Design Therapeutics, Inc. (DSGN) lists 10 active executives. The top listed executive is Aseem Z. Ansari, Co-Founder & Scientific Advisor.

Are DSGN insiders buying or selling?

Recent insider activity shows net buying of $128.18M.

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