Castle Biosciences, Inc.

Castle Biosciences, Inc.

Healthcare

NASDAQ:CSTL · NASDAQ Global Market

Market Cap $639.36M Beta 1.02 P/E (TTM) -48.2
$20.70 -1.48%

-$0.31 today

52W Low $14.59High $44.28

Vol 0.15M · Avg 0.38M

EPS (TTM)-$0.43
Medical - Diagnostics & Research

Income Statement

Follow revenue through to earnings

Review sales, margins, expenses, and profit trends to see what is actually driving reported earnings over time.

Earnings Waterfall

Revenue to Net Income

Key Ratios

EPS$-0.44
Gross Margin77.0%
Net Margin-3.8%
P/E Ratio-96.7
P/S Ratio8.9

Analysis

$339.9M of revenue converted into -$12.8M of net income for the selected period. Gross margin is 77.0% and net margin is -3.8%, showing how much revenue survives after costs and taxes. EPS is $-0.44, tying the income statement back to per-share earnings.

Income Statement

Annual data · 5 periods

MetricFY2025FY2024FY2023FY2022FY2021FY2020FY2019FY2018
Revenue
$344.2M
+3.7%
$332.1M
+51.1%
$219.8M
+60.4%
$137.0M
+45.7%
$94.1M
$809.6M$921.6M$731.2M
Cost of Revenue
$71.0M
+18.0%
$60.2M
+33.8%
$45.0M
+40.5%
$32.0M
+102.3%
$15.8M
$725.6M$804.0M$882.4M
Gross Profit
$273.2M
+0.5%
$271.9M
+55.5%
$174.8M
+66.4%
$105.0M
+34.2%
$78.3M
$8.9B$7.6B$6.2B
Gross Margin
79.4%
-2.5pp
81.9%
+2.3pp
79.5%
+2.9pp
76.6%
-6.5pp
83.2%
9.8%28.9%38.3%
Research & Development
$51.9M
-0.4%
$52.0M
-2.9%
$53.6M
+19.4%
$44.9M
+51.5%
$29.6M
$983.2M$1.3B$490.4M
Selling, General & Admin
$229.3M
+14.6%
$200.0M
+11.0%
$180.2M
+26.0%
$143.0M
+64.9%
$86.7M
$620.6M$923.0M-$1.5B
Operating Expenses
$316.0M
+20.1%
$263.2M
+8.4%
$242.8M
+36.5%
$177.9M
+50.3%
$118.3M
$5.3B$7.0B$8.7B
Depreciation & Amortization
$40.8M
+154.9%
$16.0M
+29.7%
$12.3M
+16.9%
$10.5M
+209.5%
$3.4M
$374.2M$1.2B$631.8M
EBITDA
$11.3M
-70.3%
$38.1M
+184.7%
-$45.0M
+22.8%
-$58.3M
-59.4%
-$36.6M
-$15.2B$6.8B$9.3B
EBITDA Margin
3.3%
-8.2pp
11.5%
+32.0pp
-20.5%
+22.1pp
-42.6%
-3.7pp
-38.9%
5.6%46.3%42.0%
Operating Income
-$42.8M
-593.8%
$8.7M
+112.8%
-$68.0M
+6.7%
-$72.9M
-81.8%
-$40.1M
$12.3B$14.0B-$15.7B
Operating Margin
-12.4%
-15.0pp
2.6%
+33.5pp
-30.9%
+22.2pp
-53.2%
-10.6pp
-42.6%
16.6%24.1%22.0%
Interest Income
$11.8M
-8.9%
$12.9M
+21.6%
$10.6M
+167.7%
$4.0M
+5735.3%
$68.0K
-$1.5B-$1.6B$405.0M
Interest Expense
$86.0K
-85.1%
$577.0K
+5145.5%
$11.0K
-35.3%
$17.0K
+1600.0%
$1.0K
$1.1B$1.0B$1.2B
Other Income / Expenses
$13.3M
+3.1%
$12.9M
+21.5%
$10.6M
+168.6%
$4.0M
+5797.0%
$67.0K
-$1.5B$1.4B$1.2B
Income Before Tax
-$29.5M
-236.9%
$21.6M
+137.6%
-$57.4M
+16.7%
-$68.9M
-72.2%
-$40.0M
$3.3B$4.9B$3.6B
Pre-Tax Margin
-8.6%
-15.1pp
6.5%
+32.6pp
-26.1%
+24.2pp
-50.3%
-7.8pp
-42.5%
20.8%18.7%26.2%
Income Tax Expense
-$5.4M
-261.4%
$3.3M
+3186.1%
$101.0K
+105.7%
-$1.8M
+79.7%
-$8.7M
$1.3B-$1.6B$745.2M
Net Income
-$24.2M
-232.4%
$18.2M
+131.7%
-$57.5M
+14.4%
-$67.1M
-114.6%
-$31.3M
$4.9B$4.8B$4.7B
Net Margin
-7.0%
-12.5pp
5.5%
+31.6pp
-26.1%
+22.8pp
-49.0%
-15.7pp
-33.3%
12.4%17.5%22.5%
EPS (Basic)
-$1
-225.8%
$1
+130.8%
-$2
+17.1%
-$3
-108.1%
-$1
$400.8M$703.2M$1.3B
EPS (Diluted)
-$1
-233.9%
$1
+129.0%
-$2
+17.1%
-$3
-108.1%
-$1
$766.2M$609.4M$452.6M
Weighted Avg Shares
$29.0M
+4.4%
$27.8M
+3.6%
$26.8M
+2.9%
$26.1M
+3.6%
$25.1M
$757.8M$925.8M$1.1B
Weighted Avg Shares (Diluted)
$29.0M
-0.9%
$29.3M
+9.2%
$26.8M
+2.9%
$26.1M
+3.6%
$25.1M
$1.2B$924.4M$678.0M

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SEC Filings

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How much revenue does CSTL generate?

Castle Biosciences, Inc. (CSTL) reported $344.23M of revenue in fiscal 2025.

Is CSTL profitable?

Castle Biosciences, Inc. (CSTL) reported -$24,158,000.00 of net income, with a net margin of -7.0%.

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