CRISPR Therapeutics AG

CRISPR Therapeutics AG

Healthcare

NASDAQ:CRSP · NASDAQ Global Market

Market Cap $4.80B Beta 1.70 P/E (TTM) -8.4
$49.80 -0.86%

-$0.43 today

52W Low $40.76High $78.48

Vol 1.15M · Avg 1.75M

EPS (TTM)-$5.92
Biotechnology

Management

Put operating results in leadership context

Review returns on capital, executive background, insider transactions, and growth quality to judge whether management is compounding value well.

Return Metrics

ROE, ROIC & ROA over time

Management

ROE

-30.3%

avg -8.2%

ROIC

-26.6%

avg -17.2%

ROA

-25.7%

avg -14.4%

Analysis

ROA is currently the strongest return metric at -25.7% versus its period average of -14.4%. 0 of 3 return metrics are above their quality threshold, which helps indicate how efficiently the company turns capital and assets into profit.

Management

Key executives, compensation & ownership

Management
NameTitleCompensationTenureAgeShares OwnedOwnership %

Samarth Kulkarni

Chief Executive Officer & Chairman$1.43M48$255,501.000.26%

Naimish Patel

Chief Medical Officer$858,490.0054$19,357.000.02%

James R. Kasinger

General Counsel & Secretary$780,577.0054$17,000.000.02%

Raju Yashaswi Prasad

Chief Financial Officer$779,557.0042$19,500.000.02%

Shaun Foy

Co-Founder

Chad A. Cowan

Scientific Founder54

Craig C. Mello

Co-Founder & Scientific Advisory Board Member

Daniel G. Anderson

Co-Founder & Scientific Advisory Board Member56

Emmanuelle Marie Charpentier

Co-Founder & Scientific Advisory Board Member

Matthew Porteus

Co-Founder & Scientific Advisory Board Member61

Insider Trading

SEC Form 4 transactions — last 12 months

Management

Buys

4

$52.64M

Sells

27

$17.63M

Net Sentiment

+$35.01M

Net buying

Most Active

Prasad Raju

10 transactions

DateInsiderTypeSharesPriceValue
May 29, 2026

Patel Naimish

Direct

Sell3.8K$55.62$210,577.32
Mar 23, 2026

Prasad Raju

Direct

Sell3.7K$46.78$173,460.24
Mar 23, 2026

KASINGER JAMES R.

Direct

Sell3.2K$46.78$148,853.96
Mar 23, 2026

Kulkarni Samarth

Direct

Sell10.0K$46.78$468,735.60
Mar 16, 2026

Patel Naimish

Direct

Sell3.1K$48.26$152,019.00
Mar 16, 2026

KASINGER JAMES R.

Direct

Sell3.5K$48.26$166,497.00
Mar 16, 2026

Prasad Raju

Direct

Sell4.0K$48.26$194,053.46
Mar 16, 2026

Kulkarni Samarth

Direct

Sell10.3K$48.26$499,442.74
Mar 16, 2026

Prasad Raju

Direct

Sell5.8K$48.26$282,224.48
Mar 11, 2026

Kulkarni Samarth

Direct

Sell9.8K$52.80$517,334.40

1–10 of 31

Analysis

Insiders reported 4 buys worth $52.64M and 27 sells worth $17.63M over the last 12 months. That adds up to net buying of $35.01M. Prasad Raju was the most active insider with 10 transactions.

Growth Analysis

Historical CAGR & forward analyst estimates

Metric 10yr5yr3yr Fwd Est.
EPSN/AN/AN/A
N/A3 analysts
RevenueN/AN/A+133.0%
+86.4% (12yr)5 analysts
Net IncomeN/AN/AN/A
N/A5 analysts
EBITN/AN/AN/A
N/A5 analysts

Analysis

Recent growth has been strongest in Revenue at +133.0% over three years. Forward estimates point to Revenue at +86.4% (12yr), giving you a quick check on whether expectations are accelerating or cooling.

Who manages CRSP?

CRISPR Therapeutics AG (CRSP) lists 10 active executives. The top listed executive is Naimish Patel, Chief Medical Officer.

Are CRSP insiders buying or selling?

Recent insider activity shows net buying of $75.95M.

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