Annexon, Inc.

Annexon, Inc.

Healthcare

NASDAQ:ANNX · NASDAQ Global Select

Market Cap $563.29M Beta 1.18 P/E (TTM) -4.7
$4.71 +0.21%

+$0.01 today

52W Low $1.85High $7.18

Vol 3.20M · Avg 2.55M

EPS (TTM)-$1.01
Biotechnology

Management

Put operating results in leadership context

Review returns on capital, executive background, insider transactions, and growth quality to judge whether management is compounding value well.

Return Metrics

ROE, ROIC & ROA over time

Management

ROE

-97.7%

avg -47.5%

ROIC

-91.0%

avg -93.9%

ROA

-74.5%

avg -69.3%

Analysis

ROA is currently the strongest return metric at -74.5% versus its period average of -69.3%. 0 of 3 return metrics are above their quality threshold, which helps indicate how efficiently the company turns capital and assets into profit.

Management

Key executives, compensation & ownership

Management
NameTitleCompensationTenureAgeShares OwnedOwnership %

Douglas Love

Chief Executive Officer, President & Director$1.06M58$1.25M1.05%

Dean R. Artis

Chief Scientific Officer & Executive Vice President$797,380.0065$180,093.000.15%

Ted Yednock

Executive Vice President, Chief Innovation Officer & Chairman of the Scientific Advisory Board$737,794.0068$154,161.000.13%

Jamie Dananberg

Executive Vice President & Chief Medical Officer$715,233.0068$123,582.000.10%

Jennifer Lew

Executive Vice President, Chief Financial Officer & Corporate Secretary$700,017.0053$170,700.000.14%

Michael Overdorf

Executive Vice President & Chief Business Officer$580,469.0055$182,625.000.15%

Shikhar Agarwal

Senior Vice President & Head of Commercial

Lloyd Clark

Senior Vice President of Ophthalmology Strategy & Innovation

Sunil Mehta

Senior Vice President of Medical Affairs

Henk-Andre Kroon

Senior Vice President of Translational Medicine

Insider Trading

SEC Form 4 transactions — last 12 months

Management

Buys

17

$12.35M

Sells

13

$321,415.27

Net Sentiment

+$12.03M

Net buying

Most Active

Carson William H.

10 transactions

DateInsiderTypeSharesPriceValue
May 28, 2026

Satter Muneer A

Indirect

Buy613.5K$5.41$3,319,018.77
May 11, 2026

Carson William H.

Direct

Buy8.0K$5.78$46,240.00
Apr 10, 2026

Carson William H.

Direct

Buy8.0K$6.20$49,600.00
Mar 10, 2026

Carson William H.

Direct

Buy8.0K$5.67$45,360.00
Mar 2, 2026

Dananberg Jamie

Direct

Sell5.8K$5.43$31,602.60
Mar 2, 2026

Overdorf Michael

Direct

Sell4.3K$5.42$23,517.38
Mar 2, 2026

Yednock Ted

Direct

Sell5.6K$5.42$30,167.72
Mar 2, 2026

ARTIS DEAN RICHARD

Direct

Sell5.9K$5.43$32,004.42
Mar 2, 2026

Lew Jennifer

Direct

Sell5.6K$5.42$30,162.30
Feb 18, 2026

Dananberg Jamie

Direct

Sell5.3K$5.10$26,979.00

1–10 of 30

Analysis

Insiders reported 17 buys worth $12.35M and 13 sells worth $321,415.27 over the last 12 months. That adds up to net buying of $12.03M. Carson William H. was the most active insider with 10 transactions.

Growth Analysis

Historical CAGR & forward analyst estimates

Metric 10yr5yr3yr Fwd Est.
EPSN/AN/AN/A
N/A2 analysts
RevenueN/AN/AN/A
N/A6 analysts
Net IncomeN/AN/AN/A
N/A6 analysts
EBITN/AN/AN/A
N/A6 analysts

Analysis

Analysis will appear once historical growth or forward estimates are available for this company.

Who manages ANNX?

Annexon, Inc. (ANNX) lists 10 active executives. The top listed executive is Jennifer Lew, Executive Vice President, Chief Financial Officer & Corporate Secretary.

Are ANNX insiders buying or selling?

Recent insider activity shows net buying of $62.86M.

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