ALX Oncology Holdings Inc.

ALX Oncology Holdings Inc.

Healthcare

NASDAQ:ALXO · NASDAQ Global Select

Market Cap $202.52M Beta 0.45 P/E (TTM) -1.0
$1.58 +3.95%

+$0.06 today

52W Low $0.40High $2.66

Vol 0.64M · Avg 1.01M

EPS (TTM)-$1.64
Biotechnology

Management

Put operating results in leadership context

Review returns on capital, executive background, insider transactions, and growth quality to judge whether management is compounding value well.

Return Metrics

ROE, ROIC & ROA over time

Management

ROE

-391.4%

avg 768.3%

ROIC

-262.0%

avg -126.9%

ROA

-172.2%

avg -88.2%

Analysis

ROA is currently the strongest return metric at -172.2% versus its period average of -88.2%. 0 of 3 return metrics are above their quality threshold, which helps indicate how efficiently the company turns capital and assets into profit.

Management

Key executives, compensation & ownership

Management
NameTitleCompensationTenureAgeShares OwnedOwnership %

Jason W. Lettmann

Chief Executive Officer & Director$1.02M49$293,609.000.22%

Harish Shantharam

Chief Financial Officer$642,867.0045$303,000.000.23%

Shelly Wong

Senior Vice President of Finance & Chief Accounting Officer$578,466.0049$86,805.000.06%

Shelly Pinto

Senior Vice President of Finance & Chief Accounting Officer$578,466.0049$86,805.000.06%

Barbara J. Klencke

Chief Medical Officer$262,580.0069$100,000.000.07%

Lin Yeong-Liang

Senior Vice President of Drug Safety & Pharmacovigilance

Lisa Sauer

Senior Vice President of Regulatory Affairs & Quality Assurance

Venita De Almeida

Vice President & Head of Research Program Development

Athanasios Tsiatis

Senior Vice President of Clinical Development

Sue Naim

Senior Vice President of Clinical Operations

Jeff E. Knight

Chief Development & Operating Officer54$800,000.000.59%

Insider Trading

SEC Form 4 transactions — last 12 months

Management

Buys

4

$5.16M

Sells

8

$37,794.31

Net Sentiment

+$5.12M

Net buying

Most Active

Pinto Shelly

6 transactions

DateInsiderTypeSharesPriceValue
Mar 19, 2026

Lettmann Jason

Direct

Sell12.3K$2.17$26,714.87
Mar 19, 2026

Pinto Shelly

Direct

Sell903$2.17$1,959.51
Feb 18, 2026

Pinto Shelly

Direct

Sell565$2.27$1,282.55
Feb 2, 2026

GOODMAN COREY S

Indirect

Buy3.18M$1.57$4,999,999.41
Jan 6, 2026

Pinto Shelly

Direct

Sell3.9K$1.11$4,356.75
Sep 17, 2025

Lettmann Jason

Direct

Buy71.2K$1.08$76,891.62
Sep 16, 2025

Lettmann Jason

Direct

Buy21.1K$1.07$22,460.62
Aug 18, 2025

Shantharam Harish

Direct

Buy75.0K$0.78$58,402.50
Aug 15, 2025

Pinto Shelly

Direct

Sell611$0.64$391.28
Aug 15, 2025

Lettmann Jason

Direct

Sell2.4K$0.64$1,525.43

1–10 of 12

Analysis

Insiders reported 4 buys worth $5.16M and 8 sells worth $37,794.31 over the last 12 months. That adds up to net buying of $5.12M. Pinto Shelly was the most active insider with 6 transactions.

Growth Analysis

Historical CAGR & forward analyst estimates

Metric 10yr5yr3yr Fwd Est.
EPSN/AN/AN/A
N/A2 analysts
RevenueN/AN/AN/A
N/A2 analysts
Net IncomeN/AN/AN/A
N/A2 analysts
EBITN/AN/AN/A
N/A2 analysts

Analysis

Analysis will appear once historical growth or forward estimates are available for this company.

Who manages ALXO?

ALX Oncology Holdings Inc. (ALXO) lists 11 active executives. The top listed executive is Harish Shantharam, Chief Financial Officer.

Are ALXO insiders buying or selling?

Recent insider activity shows net buying of $23.91M.

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