Agios Pharmaceuticals, Inc.

Agios Pharmaceuticals, Inc.

Healthcare

NASDAQ:AGIO · NASDAQ Global Select

Market Cap $1.72B Beta 0.59 P/E (TTM) -4.1
$29.46 +2.58%

+$0.74 today

52W Low $22.24High $46.00

Vol 1.14M · Avg 1.06M

EPS (TTM)-$7.19
Biotechnology

Income Statement

Follow revenue through to earnings

Review sales, margins, expenses, and profit trends to see what is actually driving reported earnings over time.

Earnings Waterfall

Revenue to Net Income

Key Ratios

EPS$-7.25
Gross Margin81.0%
Net Margin-680.3%
P/E Ratio-4.7
P/S Ratio127.8

Analysis

$66.0M of revenue converted into -$422.6M of net income for the selected period. Gross margin is 81.0% and net margin is -680.3%, showing how much revenue survives after costs and taxes. EPS is $-7.25, tying the income statement back to per-share earnings.

Income Statement

Annual data · 5 periods

MetricFY2025FY2024FY2023FY2022FY2021FY2020FY2019FY2018
Revenue
$54.0M
+48.0%
$36.5M
+36.1%
$26.8M
+88.4%
$14.2M
$0
$809.6M$921.6M$731.2M
Cost of Revenue
$11.5M
+176.6%
$4.2M
-56.2%
$9.5M
+457.7%
$1.7M
-90.9%
$18.8M
$725.6M$804.0M$882.4M
Gross Profit
$42.5M
+31.5%
$32.3M
+86.7%
$17.3M
+38.2%
$12.5M
+166.8%
-$18.8M
$8.9B$7.6B$6.2B
Gross Margin
78.7%
-9.9pp
88.6%
+24.0pp
64.6%
-23.5pp
88.0%
9.8%28.9%38.3%
Research & Development
$334.4M
+11.0%
$301.3M
+4.3%
$288.9M
+3.2%
$279.9M
+8.9%
$257.0M
$983.2M$1.3B$490.4M
Selling, General & Admin
$180.3M
+15.0%
$156.8M
+30.8%
$119.9M
-1.5%
$121.7M
+0.2%
$121.4M
$620.6M$923.0M-$1.5B
Operating Expenses
$514.6M
+12.3%
$458.1M
+12.1%
$408.8M
+1.8%
$401.6M
+11.7%
$359.6M
$5.3B$7.0B$8.7B
Depreciation & Amortization
$5.2M
-8.4%
$5.7M
-14.6%
$6.6M
-22.7%
$8.6M
-54.4%
$18.8M
$374.2M$1.2B$631.8M
EBITDA
-$408.6M
-156.5%
$723.6M
+309.5%
-$345.5M
-54.8%
-$223.2M
+33.9%
-$337.7M
-$15.2B$6.8B$9.3B
EBITDA Margin
-756.3%
-2738.9pp
1982.6%
+3270.6pp
-1287.9%
+279.7pp
-1567.7%
5.6%46.3%42.0%
Operating Income
-$472.1M
-10.9%
-$425.7M
-8.7%
-$391.5M
-0.6%
-$389.0M
-2.8%
-$378.4M
$12.3B$14.0B-$15.7B
Operating Margin
-873.9%
+292.6pp
-1166.5%
+293.1pp
-1459.5%
+1272.6pp
-2732.1%
16.6%24.1%22.0%
Interest Income
$56.4M
+17.3%
$48.1M
+44.2%
$33.3M
+160.6%
$12.8M
+1430.3%
$836.0K
-$1.5B-$1.6B$405.0M
Interest Expense
$0
$0
$0
$0
$0
$1.1B$1.0B$1.2B
Other Income / Expenses
$58.3M
-94.9%
$1.1B
+2802.9%
$39.4M
-74.9%
$157.2M
+617.8%
$21.9M
-$1.5B$1.4B$1.2B
Income Before Tax
-$413.8M
-157.6%
$718.0M
+303.9%
-$352.1M
-51.9%
-$231.8M
+35.0%
-$356.5M
$3.3B$4.9B$3.6B
Pre-Tax Margin
-765.9%
-2733.0pp
1967.1%
+3279.8pp
-1312.6%
+315.2pp
-1627.8%
20.8%18.7%26.2%
Income Tax Expense
-$1.0M
-102.3%
$44.2M
$0
$0
$0
$1.3B-$1.6B$745.2M
Net Income
-$412.8M
-161.3%
$673.7M
+291.4%
-$352.1M
-51.9%
-$231.8M
-114.4%
$1.6B
$4.9B$4.8B$4.7B
Net Margin
-764.0%
-2609.9pp
1845.9%
+3158.6pp
-1312.6%
+315.2pp
-1627.8%
12.4%17.5%22.5%
EPS (Basic)
-$7
-160.0%
$12
+287.4%
-$6
-49.6%
-$4
+33.5%
-$6
$400.8M$703.2M$1.3B
EPS (Diluted)
-$7
-161.2%
$12
+283.9%
-$6
-49.6%
-$4
+33.5%
-$6
$766.2M$609.4M$452.6M
Weighted Avg Shares
$58.0M
+2.1%
$56.8M
+2.1%
$55.7M
+1.6%
$54.8M
-9.4%
$60.4M
$757.8M$925.8M$1.1B
Weighted Avg Shares (Diluted)
$58.0M
+0.1%
$57.9M
+4.0%
$55.7M
+1.6%
$54.8M
-9.4%
$60.4M
$1.2B$924.4M$678.0M

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SEC Filings

Recent regulatory filings

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How much revenue does AGIO generate?

Agios Pharmaceuticals, Inc. (AGIO) reported $54.03M of revenue in fiscal 2025.

Is AGIO profitable?

Agios Pharmaceuticals, Inc. (AGIO) reported -$412,781,000.00 of net income, with a net margin of -764.0%.

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