Miles White - Chairman, Chief Executive Officer Brian Yoor - Executive Vice President, Finance, Chief Financial Officer Scott Leinenweber - Vice President, Investor Relations.

Mike Weinstein - JP Morgan Matthew Taylor - Barclays David Lewis - Morgan Stanley Joanne Wuensche - BMO Capital Markets Josh Jennings - Cowen & Co. Lawrence Biegelsen - Wells Fargo Glenn Novarro - RBC Capital Markets Bob Hopkins - Bank of America Merrill Lynch.

Good morning and thank you for standing by. Welcome to Abbott’s fourth quarter 2017 earnings conference call. All participants will be able to listen only until the question and answer portion of this call. During the question and answer session, you will be able to ask your question by pressing the star, one key on your touchtone phone.

Should you become disconnected throughout this conference call, please redial the number provided to you and reference the Abbott earnings call. This call is being recorded by Abbott.

With the exception of any participant’s questions asked during the question and answer session, the entire call, including the question and answer session, is material copyrighted by Abbott. It cannot be recorded or rebroadcast without Abbott’s written permission. I would now like to introduce Mr. Scott Leinenweber, Vice President, Investor Relations..

Thank you and good morning. Thank you for joining us. I’d like to apologize here at the start for the late start - we had a few difficulties with the phone connection. With me today are Miles White, Chairman of the Board and Chief Executive Officer, and Brian Yoor, Executive Vice President, Finance and Chief Financial Officer.

Miles will provide opening remarks and Brian will discuss our performance and outlook in more detail. Following their comments, Miles, Brian and I will take your questions.

Before we get started, some statements made today may be forward-looking for purposes of the Private Securities Litigation Reform Act of 1995, including the expected financial results for 2018.

Abbott cautions that these forward-looking statements are subject to risks and uncertainties that may cause actual results to differ materially from those indicated in the forward-looking statements.

Economic, competitive, governmental, technological and other factors that may affect Abbott’s operations are discussed in Item 1a, Risk Factors to our annual report on Securities and Exchange Commission Form 10-K for the year ended December 31, 2016.

Abbott undertakes no obligation to release publicly any revisions to forward-looking statements as a result of subsequent events or developments, except as required by law. Please note that fourth quarter financial results and guidance provided on the call today for sales, EPS and line items of the P&L will be for continuing operations only.

On today’s conference call, as in the past, non-GAAP financial measures will be used to help investors understand Abbott’s ongoing business performance.

These non-GAAP financial measures are reconciled with the comparable GAAP financial measures in our earnings news release and regulatory filings from today, which are available on our website at abbott.com.

Unless otherwise noted, our 2017 commentary on sales growth refers to comparable operational sales growth, which adjusts the 2016 basis of comparison to include results for St. Jude Medical and to exclude the impact of exchange, the current year and historical results for Abbott’s medical optics and St.

Jude’s vascular closure businesses, which were divested during the first quarter of last year, as well as the current year sales for Alere, which was acquired on October 3, 2017. Comparable growth also reflects a reduction to St.

Jude’s historic sales related to administrative fees paid to Group Purchasing Organization in order to conform with Abbott’s presentation. With that, I’ll now turn the call over to Miles..

first, the addition of Alere expands our presence in one of the few areas in diagnostics where we weren’t already a leader, the highly attractive rapid diagnostics market.

Over the past few months, the team has made good progress integrating this business and we continue to see several levers for growth acceleration, including opportunities for geographic, platform and test menu expansion.

Secondly, we initiated the launch of the Alinity platform of instruments, an integrated family of next-generation diagnostic systems for every area of diagnostics in which we compete. As we previously discussed, the global launch of Alinity will be a multi-year process.

We initiated the launch last year in Europe and will launch in additional geographies, including the U.S., over time. This highly differentiated platform promises to be a significant sustainable growth driver for this business over the coming years.

Lastly, I’ll cover medical devices, where sales grew nearly 10% in the fourth quarter led by strong growth in electrophysiology, heart failure, structural heart, neuromodulation, and diabetes care. As I mentioned earlier, adding St.

Jude was truly a game changer for us, instantly transforming us into a broad-based medical device leader with scale, presence, and a great pipeline of next-generation products. One area in particular that shined this past year was our new product productivity. In rhythm management, we closed the MRI safe product gap across our portfolio in the U.S.

including FDA approvals of our pacemaker, ICD, and CRTD devices. These approvals enhance our competitiveness tremendously in this area. In electrophysiology, we launched EnSite Precision, our best-in-class cardiac mapping system. We also launched our next generation Confirm insertable cardiac heart monitor in Europe and the U.S.

With its slimmer product profile, easy insertion procedure, and smartphone connectivity, initial customer feedback on Confirm has been very positive. In heart failure, we launched HeartMate 3 in the U.S.

This lifesaving system helps pump blood through the body for advanced heart failure patients as they await further treatment, including heart transplant. We also have an ongoing development program to expand our indications here to include destination therapy for patients where transplant isn’t an option.

In vascular, we launched Xience Sierra, the newest generation of our leading Xience stent system in Europe. Initial market feedback has been positive and we anticipate bringing Sierra to the U.S. in the next few months.

In structural heart, in addition to double digit growth, we continue to advance our pipeline in several areas, including minimally invasive new approaches for mitral and aortic valve replacement as well as tricuspid valve repair. As you can see, the combination of Abbott and St.

Jude created a best-in-class cardiovascular device portfolio with depth, breadth, and innovation to help patients restore their health and deliver greater value to customers and payors. We had a long-term strategy to become a leader in cardiovascular care. We laid the foundation over a number of years and the combination of Abbott and St.

Jude brought it to completion. St. Jude also brought us into neuromodulation where several recently launched products led to 30% growth in the fourth quarter through both share capture and market expansion.

This leading portfolio of products offers (indiscernible) relief for patients living with chronic pain and helps those suffering from movement disorders. The positive effects of these products are nothing short of amazing.

In diabetes care, sales grew 28% in the fourth quarter led by Freestyle Libre, our highly differentiated glucose monitoring system. Over the course of last year, we also achieved a number of important regulatory and reimbursement milestones for Libre. Notably in North America, we received regulatory approvals in the U.S. and Canada.

On the reimbursement front, we obtained national coverage in the U.K., France and Japan, and earlier this month we announced that Freestyle Libre obtained Medicare coverage in the U.S. In summary, 2017 was a very good year for us.

We performed well, our new product pipeline was highly productive, and we took some very important strategic steps forward which yielded both immediate results and strengthened our long-term growth opportunities.

We’re entering 2018 with very good momentum, we’re more diverse and better balanced, our leadership positions are stronger, and importantly a significant number of recent and upcoming product launches position us for strong growth in 2018 and beyond. I’ll now turn the call over to Brian to discuss our 2017 results and 2018 outlook in more detail.

Brian?.

Okay, thank you, Miles. As Scott mentioned earlier, please note that all references to 2017 sales growth, unless otherwise noted, are on a comparable basis and do not include results from our earlier acquisitions, which is consistent with the guidance methodology we utilized all of last year.

Turning to our results, sales for the fourth quarter increased 7.7% on an operational basis. Exchange had a positive impact of 2% on sales, resulting in reported sales growth of 9.7% in the quarter.

Regarding other aspects of the P&L, the adjusted gross margin ratio was 58.8% of sales, adjusted R&D investment was 6.9% of sales, and adjusted SG&A expense was 28.9% of sales.

Overall as we look at 2017, we delivered strong adjusted EPS growth of 13.5% and significantly exceeded our cash flow objectives with full-year 2017 operating cash flow in excess of $5 billion and free cash flow in excess of $4 billion.

Turning to our outlook for the full year 2018, today we issued guidance for adjusted earnings per share of $2.80 to $2.90, which reflects 14% growth at the midpoint. In terms of our 2018 sales forecast, please note that all references to sales growth rates, unless otherwise noted, are on an organic basis.

On this basis, our 2017 sales baseline would be $26.7 billion, which excludes sales from Alere, or rapid diagnostics as we call it, which we acquired in the fourth quarter of last year, and also excludes sales from our former medical optics and vascular closure businesses, which we sold during the first quarter of 2017.

So for the full year 2018, we forecast organic sales growth of 6 to 7%. In addition, we expect rapid diagnostics to contribute sales of a little more than $2 billion for the full year 2018.

Based on current rates, we would expect exchange to have a favorable impact of a little below 2% on our full year reported sales with more than half of this favorable impact driven by strengthening of the euro.

As we’ve discussed previously, when the euro moves, the fall through impact on our results is modest, taking into account our European cost base and our hedging programs. Before I review our outlook for the P&L, I’d note that we’ve reclassified certain pension-related items in order to comply with recent changes in pension accounting standards.

As a result, approximately $150 million of net pension-related income has been removed from operating lines of the P&L, primarily cost of goods sold and SG&A expense, and now will be reported as non-operating income.

With that in mind, we forecast an adjusted gross margin ratio of somewhat above 59% of sales for the full year, which reflects underlying gross margin improvement across our businesses.

We forecast adjusted R&D investment around 7.5% of sales and adjusted SG&A expense of somewhat above 30.5% of sales, which reflects the pension-related reclassification I just mentioned as well as incremental investments in the businesses to support recent product launches and to further strengthen our pipeline.

We forecast net interest expense of around $775 million. This forecast includes the net interest impact of $4 billion of debt that was repaid earlier this month as well as anticipated additional debt repayments throughout 2018.

We forecast a gain of approximately $5 million on the exchange gain/loss line of the P&L for the full year 2018, and around $110 million of non-operating income which includes, as mentioned earlier, pension-related net income in accordance with the recent changes in accounting guidelines. Lastly, as a result of U.S.

tax reform and our forecasted mix of global income, we forecast an adjusted tax rate of 14.5 to 15% for the full year 2018. Turning to our outlook for the first quarter of 2018, we forecast an adjusted EPS of $0.57 to $0.59.

In terms of our 2018 first quarter sales forecast, please note that the first quarter 2017 organic sales baseline would be $6.15 billion which, as we commented earlier, excludes sales from our former medical optics and vascular closure businesses which we sold during the first quarter of last year.

On this basis, we forecast organic sales growth of 6 to 7%. In addition, we expect rapid diagnostics to contribute sales of a little more than $5 million in the first quarter. At current rates, we would expect exchange to have a positive impact of around 3.5% on our first quarter reported sales.

We forecast an adjusted gross margin ratio of somewhat above 59% of sales, adjusted R&D investment around 7.5% of sales, and adjusted SG&A expense of around 33% of sales. Lastly, we forecast net interest expense of around $200 million in the first quarter.

Before we open the call for questions, I’ll now provide a quick overview of our first quarter and full year organic sales growth outlook by business. For established pharmaceuticals, we forecast high single digit sales growth for both the first quarter and the full year.

In nutrition, we forecast low single digit sales growth for both the first quarter and the full year.

In diagnostics, we forecast organic sales growth of mid-single digits in the first quarter and mid to high single digits for the full year; and in medical devices, we forecast sales to increase mid to high single digits for both the first quarter and for the full year. With that, we will now open the call for questions..

[Operator instructions] Our first question comes from Mike Weinstein from JP Morgan. Your line is open..

First off, congratulations on a very nice close to 2017.

I think it’d probably be helpful, because the fourth quarter of ’16 to the fourth quarter ’17 has some moving parts, what do you think the clean organic performance was for 4Q17?.

Yes Mike, I would just chime in - there are a couple but they’re relatively modest. As you know, St. Jude had a battery recall in the fourth quarter of last year which suppressed that baseline a bit, and we had a little bit of timing in EPD, but other than that, that’s about it. Our organic growth would be around 7% this quarter - really strong..

And the confidence in the 2018 outlook, Miles, that the 6 to 7%, which I think if you would have surveyed the street before, they would have said you guys would have said mid-single digits, so obviously this is at the upper end or more bullish than that, is it the momentum that you’re seeing particularly in the device side of the business, and could you speak specifically to a couple of product launches? One of them I think everybody would like to hear about is Libre; another one is Confirm, which our check suggests is off to a very nice launch..

Yes, I’ll tell you, look - the forecast we put out, it’s a strong forecast. It just is, I mean relative to peer groups, competitors, segments, the whole thing, and even relative to us. To be honest, even looking at that, yes, I feel pretty confident about it.

I don’t know the unknown, I don’t know what exchange may or may not do - that’s always unpredictable, but based on everything we know at this point, my view is yes, 6 to 7, and probably closer to the high end of that.

If I look at the underlying performance of the business and in different segments, and I’ll just recap some of this, the drag on some of the growth here has been in nutrition, and even that is sequentially improving.

The situations that we’ve seen that have set that business back a little bit have all improved and are all improving, so I think first of all, that’s a good omen. Secondly, in all the other areas, take EPD, very sustainable growth. They had a very strong fourth quarter - I think it was 14%.

I don’t expect 14 for the whole year ’18, but let’s face it - they’re running strong. Then I look at diagnostics and devices and they’ve both got just a tremendous bunch of new product launches, and they’re not flash in the pan product launches. These are going to sustain growth over a number of years because these are big and broad product launches.

The Alinity product launch, I think is going to make a big, significant difference in diagnostics. I think we’re going to see increasingly better performance out of Alere. But look, Alinity is across six segments of diagnostics, so I think that’s a pretty sustained momentum.

They’ve been doing a terrific job, frankly, in the 6 to 8% growth range with a lot of, I’d say, aging systems and older systems, and now they’ve got an entirely brand-new product line out there in all categories, so I think that bodes well. Then, I finally look at the whole cardiovascular device area.

You’ll recall, Mike, many people challenged whether St. Jude was really growth, and there was a lot of grumbling a year ago about that acquisition. Sequentially over the course of this year, St. Jude’s going from first quarter 2.4% to 4% in the second quarter, 4.2% in the third quarter, and 10% in the fourth quarter.

I won’t tell you that I think 10% is sustainable for the year, but they had a 10% fourth quarter and they didn’t have to stretch to do it, and the product launches and approvals, mainly the product approvals particularly in the U.S.

that I forecasted to you in both July and October, all happened, and there was some skepticism about that because of the situation in Somar but, frankly, our team has done a terrific job in Somar and a terrific job communication with our U.S.

regulators, and we got all those product approvals and those launches are all out of the blocks and going well. So you know, knock on wood - I looked into 2018 and it all feels remarkably strong and sustainable, and I think that’s terrific. Tax reform was a nice boost, and there’s a lot of things here that are all looking up.

Then I finally come to Libre, which--you know, I enjoy the fact that every time something is announced with Libre, it’s a surprise to somebody because everybody seems to have such low expectations for it, and I think we’re going to continue to surprise people in that category. We’re investing several hundred million dollars in expansion.

This is a big product. I think you estimated at one point $50 million to $100 million in the U.S. this year - I think that’s a good range of estimate. But you know, frankly, it’s going strong. We’re adding probably 50,000 customers a month right now and that’s increasing, and that was primarily Europe. That doesn’t even reflect much U.S. yet.

So as we came out of the fourth quarter, the growth rate of that product is just tremendous and we’ve got a series of enhancements and approvals and additions to it coming that only make it better.

As I said, it’s not an niche product - it’s a mass market product, because there are tens of millions of Type 1 diabetics, and frankly the same in Type 2s trying not to be Type 1 diabetics, and I’m one of them, so I wear the product, I live the product, I know the product, and I think this product has a long track road ahead of it.

So as I look at all the growth drivers of the company and then some of the elements of St. Jude, like neuromodulation and structural heart and other things, I think there is just an awful lot of growth here.

So I go into ’18, I look at the numbers that we forecasted, and yes, I feel pretty confident about it, so at this point I’m looking at the success we’re having with cash flow and the balance sheet, investment in expansion, investment in capacities, investments in R&D and SG&A, which I put more money into, and everything looks pretty good. .

Miles, if I could ask--.

I realize it was a long answer, but you kind of asked a big question..

No, no, that was perfect, thank you. Just so you guys know, the sound quality isn’t great on our end, so just FYI. Miles, I did want to ask you about capital allocation and the benefit of tax reform. Tax reform is going to lower your overall tax rate in 2018 by 150 to 200 basis points.

You’re also getting access to previously trapped cash in your global cash flows going forward. Can you just talk about what you plan to do with the trapped cash and then how the access to global cash flows changes at all your capital allocation plans? And then I’ll drop, thanks..

Yes well, it’s not trapped anymore. It’s terrific to have access to it, I have to say. I’m pleased with where tax reform came out. As a multi-national and a company that had a lot of debt in the last two years because of the acquisitions, I had concerns about some of the structures they were looking at, but it all turned out pretty good.

I think it will stimulate a lot of growth and investment in the U.S. in particular, and you can see that in a lot of the things that companies are communicating, and the same is going to be true for us. As far as capital allocation, Brian mentioned in his remarks we were up to a gross $28 billion of debt because of our acquisitions of St.

Jude and Alere, and a little bit of lingering debt we had just over time, and we just paid off $4 billion of that so we’re down to $24 billion. Over the next six months, we’ll pay off probably $3.5 billion to $4 billion more, and we’ll be down to $20 billion by the end of ’18. The cash flows in the company are strong.

Brian’s run a program with our EVPs to be very conscious of cash generation, and that’s been extremely successful, and our cash flows and profits and so forth right now are as strong as they’ve ever been. So as I’ve said, we’re going to make a priority out of getting that cash or getting that debt down to a more balanced level.

We will--we’ve already exceeded the targets that the rating agencies had for us, and we’ll be below--on debt to EBITDA, we’ll be below 3 at year-end, and on a net debt basis we’ll be below 2.

So we’ll be in a very strong metrics position at year-end, and that puts us in, let’s say, a position to be at a more normal capital allocation viewpoint at that point. We raised our dividend in December by 6%.

I’d anticipate we’ll raise it again at the end of the year probably more than that, because we like to maintain a payout ratio of a little better than 40% of EPS.

So I think our capital allocation, our cash flow is strong, we’re pushing down the debt fast, faster than we anticipated by at least 18 months, so all of that right now is frankly looking quite good, largely due to the tax reform and the management of cash flow here..

Thank you. Our next question comes from Matthew Taylor from Barclays. Your line is open..

Good morning, thanks for taking the question. The first question I wanted to ask was specifically on diagnostics. I guess I was just a little intrigued by the fact that the guidance you gave for the year implies some improvement, and you also talked about that in your comments. I wanted to explore two things.

One is can you talk about how the Alinity roll-out could cadence through the year, and then secondly, now that you have had Alere or rapid diagnostics under your belt for a little while, can you talk about the state of that asset and how you expect that to grow over the coming years?.

Yes, thanks Matt. Let me start with Alinity. First of all, it’s six different systems, two in particular that are in the core laboratory, one that will address transfusion, one that will address point of care testing, one that will address hematology, and one that will address molecular diagnostics, so there’s multiple dimensions to this.

You’ve got approvals around the world. They’re all approved in Europe at this point. A couple are approved in the U.S. We expect more approvals the following year. We tend to be pretty much on those approvals.

The menu expansions in our development have gone extremely well in the last, say, 10 to 12 months, so they’ve got very full menus, and therefore the pace of introduction can go much faster because accounts don’t really want to address change until they’ve got full menus, or close to it, so that momentum picks up.

Then you’ve got to deal with the life cycle of contracts that are out there in the world. Now, today we’ve got, I want to say, 25, 26, 27,000 instruments out there in these main categories, main core lab categories, and my goal is to replace that entire base and of course take a fair amount of share over the next five to 10 years.

So there’s a ramp there, there’s a scale there. It’s a significant scale, and our attention now is all about scale-up and all about pace and magnitude. This is not going to be some incremental, slow-rolling thing.

It starts that way initially - it starts as a slow roll, and then it’s going to pick up tremendous momentum because it’s our intent to replace that entire base and frankly take a lot of share with it. So I think we’re in a really great position with Alinity. Our challenge now is just mass scaling as we attack that market.

On Alere, I’d say our team has done a terrific job. We have an entirely new, from Abbott, management team there. I’d say their progress in terms of integration, reorganization, etc. has gone extremely well.

Literally within a couple of weeks, we reorganized the entire company into business units, fully integrated business units with management teams and so forth. I’d say that our assumption of the business has gone at warp speed and gone well. We’re ahead of schedule on literally everything, on target on our synergies.

We’re ahead of our targets on sales and profit. Flu and strep seasons in the U.S. have aided that to some degree, but thus far I’d say everything is sort of on point as we’ve projected. Beyond that, I don’t have a lot more detail to give you, other than so far, so good, and I think our transition management has been excellent.

It’s been that way with St. Jude too. What we did at St. Jude, we’ve done faster at Alere, and St. Jude was pretty fast. We went through sort of the same things with St. Jude - we reorganized a lot of businesses there into fully integrated business units, we did it in the first six months.

That’s usually very disruptive, but we managed to do it without disruption, and we did it with Alere in a matter of weeks, so I’d say we’re in a strong position. I’m very pleased with the management team and how rapidly it’s up to speed. We’ve got a couple of new hires on some of the business, but I’d say this team has gotten up to speed quick..

Thanks. One follow-up - this is probably the most pleased I’ve heard you sound in while on how things are going and the results kind of speak for themselves, but I know you’re never satisfied.

What areas would you point us to where things aren’t going well, that you want to improve, and how do you think about dropping all this good growth on the top line through to the bottom line versus investing in all the things that you have to invest in now?.

Well, I’d say two things. We’ve still got improvement to make in nutrition, and we know that and our nutrition team knows that. We’ve had a lot of discussion about that - I’ve personally talked to our (indiscernible) around the world and so forth, and there’s no point in having your (indiscernible), we simply want to do better.

I’d say even where our growth rates are right now, sequential improvement is a plus. Now, there are a number of places we’re pretty positive and pretty happy with performance. I’d say the U.S. stands out as executing really well.

There’s a number of countries around the world executing well, and the ones that had difficulty are improving, so that remains a point of attention to us. I’d say in terms of the happy column, a lot of our success right now and what we’re focused on is organic growth. We’ve never had such productivity out of R&D at Abbott, and frankly so has St.

Jude, and I now consider them Abbott. What St. Jude had said about their pipeline to the street over a number of years is true - they had and do have a terrific pipeline of products.

We’ve gotten the approvals, we’ve closed the gaps where they had deficiencies, and there’s a lot of growth there, so what I’m particularly happy about is that the organic growth opportunity here across all of our businesses - nutrition, EPD, pharma business, the new product launches in diagnostics and devices, including St.

Jude and Alere, it’s just--its broad and it’s deep, and it’s exciting to have that much innovation and new product to be launching. So our challenges aren’t so much fixing problems or deficiencies; our challenges are how fast we can scale and how fast we can run.

I’m pretty confident that it’s sustainable and it’s sustainable for a long time because it is organic growth of new products, so I’m pretty happy about that. I’m not out looking for M&A and I don’t have any significant M&A on the radar screen - in fact, I don’t have any M&A on the radar screen because I want to hit those debt targets by year-end.

Our targets are more aggressive than the ratings agencies. I want to get back to where our capital allocation flexibility is as flexible as it’s ever been, and I want to get their fast and I’m going to get there fast.

So you know, I think our challenges are how to keep the pedal down on that growth, because all of these businesses have opportunities at the same time and some of it is some fairly significant scale-up, and Libre is a tremendous opportunity. It’s a mass market product and it’s unlike any other medical devices.

Medical devices by nature are sort of niche therapies - this one is not, and this one has a totally different rhythm to it, and the pace of scale and the magnitude of opportunity is more like tech than it is med-tech.

That’s an interesting challenge for us, it’s a positive challenge, it’s a good challenge, and fortunately we’ve got such strong cash flow, we can afford the capital investment that we want to spend while we’re paying down our debt and paying our dividend and so forth. So I mean, as challenges go, that’s a pretty nice set of challenges.

You don’t lose sleep on those..

Thank you..

Thank you. Our next question comes from David Lewis from Morgan Stanley. Your line is open..

Good morning. Miles, there’s a lot of conversation this morning on growth, but it was fairly robust EPS guidance for Abbott to start the year. I think for us, what’s interesting is unlike a lot of your peers who are dropping through all the tax down to the bottom line, you’re reinvesting, which makes sense given your premium growth.

But I wonder if you can sort of give us a sense of where that reinvestment is going, and given your flexibility, how you’re feeling about this sort of mid-teens EPS growth over the next couple of years..

Well nice try - I don’t give guidance that far ahead. Yes, it’s a good question. I have seen that a number of companies have dropped through quite a lot of tax benefit to the bottom line, and frankly I expect to see that. I mean, there are some industries and some businesses that really benefited from tax reform.

If the primary source of your sales and profits is the U.S., obviously you got a really demonstrative benefit. If you’re a multi-national or you had a lot of debt or something, it’s not as demonstrative; but now having said that, we’ve dropped through some of that tax benefit into our EPS, and I think that’s reflected in our guidance this morning.

I did direct a significant amount of the benefit from tax into R&D and SG&A, and I think that’s warranted given not only the new product launches and how fast we want to run with some of these, but--so I’ve directed some of the benefit to increased R&D investment, and you can imagine--I mean, I’ve directed some of that at diabetes care and Libre, I’ve directed some of that at neuromodulation and other cardiovascular products, I’ve directed a fair bit of it at SG&A expansion and so forth.

When you’ve got these kinds of opportunities, you’ve got to invest in them and put fuel behind them, and fortunately tax reform has given us that ability. We will spend some of that money investing in manufacturing in the United States as it’s predicted that that would happen.

We will - I won’t tell you where or what products and so forth, because I don’t want to forecast that to competitors and so forth, but in fact the U.S. will benefit, as will some locations overseas where we’ve got already existing capability, facilities, expertise, etc.

But we are directing a fair amount of this to help ensure we’ve got not only a sustainable product pipeline and rapid innovation and enhancements to products, but that we’re also doing our best in marketing areas and so forth to maximize the opportunity that’s in front of us as rapidly as we can.

We don’t want to think about it so incrementally, because I think sometimes when you’ve got these new products and opportunities, you’ve got to go hard and fast, and I think when you do that, you establish a better share position, a better market position, a better use position with customers, regulators, etc., and that’s much more sustainable over time.

So as you ask me, I think if we get our job done particularly in the areas where we just--you know, that I’ve just highlighted, which is a lot, I think our growth rates are pretty sustainable.

We start every year with a double digit earnings growth target, and as we’ve indicated this year on an apples-to-apples comparable growth basis, we expect 6 to 7%, and I’m in the upper half of that range in my beliefs. But I’d like to see that growth rate increase, even substantially going forward. We’re always trying o be double digit earnings.

I’m not concerned about having a double digit earnings growth rate on a sustainable basis for the next few years. I want to drive the top line so that I can sustain that at an even higher rate, and that’s where my focus is..

Okay, that’s very clear. Thanks for the color, Miles. I think St. Jude has gotten a lot of attention on the call but Alere less so. What’s your focus for 2018 for Alere? Can this asset definitively get back to underlying growth in ’18, and how quickly can Alere get back to what you would think is market growth for point of care? Thanks..

Well, I’d say slower than St. Jude. St. Jude, as you all remember it, it went through about a four or five-year period where it didn’t have much growth and the street was unhappy with that, and it even missed its earnings targets a couple of times.

What they were right about was they had a robust R&D pipeline and a product pipeline, and they were right about that and I think the people that led and managed St. Jude should feel vindicated about that. We do, because there was a fair amount of concern and criticism when we acquired St.

Jude, but frankly as you can see in the numbers, there’s growth here and there’s going to be growth here, and it’s not just small incremental growth. It’s significant, and I’m really happy with the performance of St. Jude. I think Alere is a little longer story. The company had a lot of internal operating challenges.

It hadn’t been invested in, so I think pipelines are going to take a little longer to develop. I think restoring the cohesiveness of performance of functions in the business, in some of the business, it’s going to take a little longer.

So I expect Alere to emerge, I’m going to say over two to three years, because we want to put more investment into new products, refreshing products, R&D, SG&A, etc.

We do have some rationalization to do - that doesn’t mean restructuring, that means the integration of those functions and businesses, and figuring out what are old products, what are new products and so forth. I think Alere will be a little slower emergence than St. Jude has been. St.

Jude sort of exploded on the scene here over one year, and I don’t think Alere will explode on the scene but I don’t think Alere is going to be flat either. I think we believe there’s a lot of growth here in this entire rapid diagnostic and point of care space.

I think there’s a lot of growth, and I think that growth is sustainable over many years, but I don’t think it’s going to be--I’m not going to be telling you the same story about Alere at the end of the year. At the end of ’18, I’m going to tell you we had a good year, it tracked better than we thought, it’s showing growth.

I’m going to tell you all those things at year-end, I’m pretty sure, and we love the underlying assets and products and so forth. I mean, that’s all going to be true, but I think operationally it’s going to take a little longer to get this back on an investment cycle in products and launches and so forth that we’ll want to see.

The good news is we’ve got so many other opportunities at the same time that I think it’s nicely staged. You don’t want everything to show up at the same time, so I think it’s nicely staged to help sustain the growth in diagnostics while they're dealing with the scale-up of Alinity..

Great, thanks Miles. Congrats on the quarter..

Thank you. Our next question comes from Joanne Wuensch from BMO. Your line is open..

Good morning, and thank you for the question. Very nice quarter. Can we turn a little bit to EPD? That area of growth tends to be a little bit of a black box for investors. How do we think about the sustainability of that growth rate? This is the second quarter in a row of mid-teens growth..

You know, Joanne, I think the fundamentals underlying the markets drive an awful lot of the growth. You know, the managers in that business and I sort of have this ongoing debate - I’m always chronically dissatisfied and they’re always telling me, hey look, we’re really growing fast here.

But the fact is the underlying dynamics of the market drive a lot of the growth because we’ve selected markets and countries, emerging markets in particular that have growth characteristics which I characterized in my remarks.

So the underlying fundamentals of those markets are all very positive in terms of growing healthcare systems, growing middle class, spending on healthcare, etc., but succeeding in those markets requires a certain amount of presence and strength and scale, meaning you want to be in the top five competitors in most of these markets.

China is a little different, but you want to be in sort of the top five competitors. You want to have very broad product lines and you want to have some depth in various therapeutic categories, and you want to have a strong brand.

I think our teams around the world have done a super job at that, and I think there’s countries where we believe we can do even better, a lot better. So I’d say, first of all, the underlying dynamics are strong. We’ve put a fair amount of emphasis in renewing and broadening our products.

We’ve put a lot of attention into our own, let’s call it development productivity, registration productivity, etc. We’re putting more and more investment into India and our distributor organizations to do just that, because we believe we can and should.

We’re putting a lot of attention on gross margin management to improve our gross margins, whether in procurement or things that we source from third parties that we should do ourselves, and so forth.

So there’s a lot of emphasis on margin improvement, and frankly the margin is already good, better than good, but we know that there’s opportunity to improve it still further. A lot of people think of generics as commodity, generics that don’t make much money. These are branded generics where the brand matters.

It’s sort of an OTX type thing in a lot of these markets, and we make pretty good profits here, so the characteristics of these markets have been that. That said, the last couple quarters had some anomalies that bumped these numbers up and down.

We went through a couple of disruptions in India, for example, which is a big part of our business, where we went through the demonetization issue and then the GST tax thing. We actually managed that really well, I think, but that affected inventory management by wholesalers and distributors, which are a big part of our business system here.

So sometimes I think we’re going to see some of these quarters look very up, and other times they’re going to be a little less up, but they’re always up. You know, I think--I don’t think the 14% we saw in the fourth quarter is something we expect every quarter.

If it starts to happen three or four quarters in a row, I’m going to be back with my managers, saying I think you were a little conservative, but I think it’s a double digit grower.

I think it’s easily sort of 9 to 11% on a very sustainable basis on the sales line, so a lot of that is fundamentally in the markets and then we’re pressing to kind of broaden our product lines and gain share because of the way we manage the business..

Thank you. As my follow up, neuromodulation sales were up 30% in the quarter after being up 50% for the beginning portion of the year. How do we think about that growth going forward, and there was a lot of good buzz coming out of NANS.

Could you please update us on that?.

Yes, I’m going to have Scott help me with that, but--because I asked the same thing. I said, jeez, why are we down to 30%? It’s because of the comparison to this fourth quarter last year. Scott can give you a little color on that, but the growth rate here remains strong and the opportunity remains strong.

This is one of the bright--well, we’ve got a lot of bright spots, but this is one, clearly.

Scott?.

Yes Joanne, as you recall, we launched first in deep brain stimulation products in the fourth quarter of last year, to Miles’ point. Obviously the business is coming off a great year - we’re number one now in the chronic pain segment. We do expect to capture more share next year.

The market is growing in the low teens and we expect to grow faster than that..

Perfect, thank you very much..

You’re welcome, thank you, Joanne..

Thank you. Our next question comes from Josh Jennings from Cowen. Your line is open..

Hi, good morning. Thanks for taking the questions, and congratulations on the strong finish to 2017. I wanted to start back on St. Jude. You guys laid out some synergy targets around the acquisition. I just wanted to get an update on whether or not you think that there is upside to those historic targets, particularly on the revenue synergy side.

We’ve been assuming revenue synergies hitting in year two, but are you already seeing revenue synergies come? Also just on the margin contribution, with the rebound in top line growth for the St.

Jude franchise, is it safe to assume that the margin contribution outlook for that unit in 2018 is going to step up nicely?.

This is Brian. I think those are the right assumptions. We’re right on with our synergies as we’ve tracked. We’ve always said $500 million by 2020. We had a great year, we executed very well. We integrated and achieved our synergies, expect that to continue, and that’s incorporated into our guidance.

As Miles discussed earlier, we’re very excited about the acceleration of top line growth here, and there’s a lot of opportunities and I think the continued growth and sequential growth momentum ’18 over ’17 should be accretive to the operating margins, not only for that business unit but for Abbott as well..

Thanks. Just a follow-up one on nutrition. The food safety law took effect in China on January 1.

I know it’s very early, but can you help us think through what you’re seeing initially and what you expect to see over the next couple of quarters in the pediatric China market, and also an update on nutritional pricing in the U.S.? Thanks for taking the questions..

I’ll answer part of that and then I’ll phone a friend here at the table.

I’d say first of all, I personally was concerned that this switchover in the food safety law, what we had to all do to comply with product labeling in a number of products and so forth, I was afraid it was going to be terribly disruptive, and it turns out we’ve already experienced the disruption in the past two years as the market was flooded with many products and a lot of volume and a lot of channels and so forth.

The single biggest issue we all had to deal with was reregister products and comply with the elements of the law, and all of our concerns were would we get our products through the regulatory bodies in China and be ready for that transition, and the answer is we made it. So you know, I think that, I’m happy with.

We’ve been careful to monitor our inventories of previous product versus new product, etc., so to the extent that we can have visibility to that, I think we’re comfortable with how that transition has gone.

I think we’re not seeing the kind of disruption that we might have or that we’ve seen in the last couple years, so thus far I’m glad we don’t see unpredicted disruption, so hopefully we can now stabilize back into a more normal, call it competition in the market.

It’s a very, very dynamic market anyway in terms of channels and numbers of competitors and the intensity of competition and so forth. We didn’t need the disruption of the food safety law, but I think that’s stable and kind of behind us at this point.

Brian or Scott?.

Sure. On the U.S. side, you asked about the price, and I would just say we’ve never historically really relied on price.

It’s about volume, and we had a great year in our pediatric business in the U.S., and that’s all about share capture in the infant milk formula market part of the pediatric business, with innovations that we introduced, and we want to continue staying to be a share leader there.

But also, bright spots there in that pediatric portfolio are Pedialyte and Pediasure, which also have done quite well in the U.S. and are great brands for us. Then I think the story in the adult is we knew we had some adjustments to make. We’re making the right adjustments.

We know we have some innovations coming and we’re seeing sequential improvement even here in the fourth quarter ’17, and we want to continue to sustain that momentum and compete on share and market expansion on the adult, because we just typically hadn’t relied on price in the U.S., or anywhere for that matter. .

We’ve gained some share back in adult - that’s nice to see. I think the team’s done a terrific job in the ped market, and we remain the clear leader in that market. At this point, as Brian said, we’re not relying on price. I think there’s a clear value proposition to be marketed out there, and we haven’t tried to stretch that, nor will we. .

Thank you. Our next question comes from Lawrence Biegelsen from Wells Fargo. Your line is open. .

Good morning guys. Thanks for fitting me in. I’ll just ask two quick product-related questions and drop. CRM, I think you grew about 2% in the fourth quarter.

Is that how we should think about 2018, or do you think that could better? Then there was a question asked earlier on Confirm Rx, maybe just setting expectations, could you do, say, $50 million in 2018 on that product? Is that realistic? Thanks for taking the questions and congrats on the quarter..

Thanks Larry. Yes, I think on CRM, you’re about right - we would expect something in the low single digits on that front. To your point, Confirm, really great opportunity. Obviously we’re still early in the launch of that, first quarter. The feedback, though, we’re getting from physicians on that one is very positive.

This is the only device out there that’s smartphone compatible, so there’s a big benefit on the patient side of it as well. Your forecast on that one, I think seems reasonable as well..

Thanks for taking the questions, guys. .

Thank you. Our next question comes from Glenn Novarro from RBC Capital Markets. Your line is open. .

Hey, two quick questions me as well, and both are for Brian. Brian, the weaker U.S. dollar has become a tailwind to the top line. Does any of that fall to the bottom line, or is that completely hedged away - question one. Then number two, the lower tax rate for this year, is this a sustainable new run rate for the next couple years? Thanks..

Sure. Let me take the exchange question. As always, it’s early in the year, so we’re reluctant to necessarily flow what’s through there. It’s a little modest. We know we have the hedge there, so we have a modest impact from the sales I quoted. You know, I think Miles has said this before - let’s see how things go.

If rates hold and things pan and history is an indicator, it’s similar to last year, we may see some of those flow through; but I think it’s just too early. There’s a lot of events that we watch throughout the year. Go ahead, Miles..

Yes, let me just add one comment to that. As you plan a year, we all can calculate what we believe our tax reform impact is going to be given our geographic mix and so forth, as you know, and then there’s exchange. If you’re a multi-national, you’ve got a lot of currencies to deal with. It’s not so predictable.

The exchange happens to us a lot of times, so we try to prepare for that with hedges.

That said, going into the year, what we chose to do was say, listen, we’re going to put some of the tax benefit from tax reform into the EPS, and we’re going to put some of it into investment, as I described earlier, because that we can forecast, we can predict, it’s knowable.

Exchange isn’t so knowable, so if exchange continues to benefit us, there’s really not enough time in a given quarter or year to reliably invest back the benefit of exchange, so the likelihood is if exchange runs better than we forecasted at this point, the investor is likely to see some of that.

Obviously we hedge some of it to protect the stability of earnings, but you can’t hedge it all, so if we are favorable, yes, you’ll probably see it..

And on the tax rate?.

Sure. As I mentioned earlier, the range we got was 14.5 to 15% for ’18. There’s a lot of moving parts to tax reform.

I’d just note that regulations are still being formed, interpretations are ongoing, but from where we sit today, we believe we should generally be in the same ballpark of this range and we’ll provide further updates as we learn more too, as the tax laws unfold here. .

Okay. Thanks Miles, thanks Brian..

Thanks Operator, we’ll take one more question..

Thank you. Our final question comes from Bob Hopkins from Bank of America. Your line is open. .

Thanks very much for fitting me in. Just two quick questions. One is on emerging markets.

Just wanted to see what emerging market growth was in the quarter and if that accelerated in fourth quarter versus earlier in the year, and then what your outlook is for 2018 from an emerging market perspective, because it seems like things have been really going well in emerging markets generally. That’s just the first question..

Yes, I think that’s a fair characterization. Generally when it’s quiet, things are going good in emerging markets, and it’s been fairly quiet. We did deliver double digit growth in emerging markets this quarter. To Miles’ point, there’s a lot of strong fundamentals in those markets that would point towards growth going forward..

Then the other one I wanted to ask about was just back on Freestyle Libre, I think you mentioned earlier in the call that you’re bringing on 50,000 new customers, I believe you said a month..

A quarter..

A quarter? Okay, that makes--.

Yes, I’m sorry if I misspoke. It’s per quarter..

Okay, that makes more sense, but still a big number. I assume right now the majority of that obviously is outside the United States. Can you give us a sense as to the pace of your sign-ups in the U.S.

and what you think for 2018 from a patient perspective for Libre in the U.S.?.

Yes, I would just say, look, we launched pretty much right at the end of the year. Obviously there was very modest sales in the fourth quarter number there. Without giving a number, I would say the strips are basically tracking right with our expectations.

I think Miles had mentioned a quarter or so back when asked what a reasonable estimate for year one sales would be, and it was agreed upon it’d probably be in the $50 million to $100 million range, and that’s still where we sit today..

Okay, thank you very much..

Very good. Well, thank you, Operator, and thank you for all your questions. That concludes Abbott’s conference call. A replay of this call will be available after 11:00 am Central time today on Abbott’s Investor Relations website at abbottinvestor.com and after 11:00 am Central time via telephone at 404-537-3406, pass code 8277348.

The audio replay will be available until 10:00 pm Central time on February 7. Thank you for joining us today..

Ladies and gentlemen, thank you for participating in today’s conference. This does conclude the program and you may all disconnect. Everyone have a wonderful day..