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Healthcare - Biotechnology - NASDAQ - GB
$ 1.51
-3.82 %
$ 84.2 M
Market Cap
-13.73
P/E
1. INTRINSIC VALUE

This DCF valuation model was last updated on Jul, 6, 2025.

The intrinsic value of one TLSA stock under the worst case scenario is HIDDEN Compared to the current market price of 1.51 USD, Tiziana Life Sciences Ltd is HIDDEN

This DCF valuation model was last updated on Jul, 6, 2025.

The intrinsic value of one TLSA stock under the base case scenario is HIDDEN Compared to the current market price of 1.51 USD, Tiziana Life Sciences Ltd is HIDDEN

This DCF valuation model was last updated on Jul, 6, 2025.

The intrinsic value of one TLSA stock under the best case scenario is HIDDEN Compared to the current market price of 1.51 USD, Tiziana Life Sciences Ltd is HIDDEN

2. FUNDAMENTAL ANALYSIS

Price Chart TLSA

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$1.8$1.8$1.6$1.6$1.4$1.4$1.2$1.2$1.0$1.0$0.8$0.8$0.6$0.615 Jan15 JanFeb '25Feb '2515 Feb15 FebMar '25Mar '2515 Mar15 MarApr '25Apr '2515 Apr15 AprMay '25May '2515 May15 MayJun '25Jun '2515 Jun15 JunJul '25Jul '25
FINANCIALS
0 REVENUE
0.00%
-18 M OPERATING INCOME
-23.30%
-17.2 M NET INCOME
-11.98%
-15.7 M OPERATING CASH FLOW
19.97%
-1.25 M INVESTING CASH FLOW
68.64%
40 K FINANCING CASH FLOW
172.73%
0 REVENUE
0.00%
-10 M OPERATING INCOME
-416.66%
-10.9 M NET INCOME
-495.89%
-7.7 M OPERATING CASH FLOW
-478.55%
-513 K INVESTING CASH FLOW
-68300.00%
-55 K FINANCING CASH FLOW
-14.94%
Balance Sheet Tiziana Life Sciences Ltd
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Current Assets 7.34 M
Cash & Short-Term Investments 1.18 M
Receivables 6.05 M
Other Current Assets 102 K
Non-Current Assets 4.85 M
Long-Term Investments 4.55 M
PP&E 293 K
Other Non-Current Assets 0
9.71 %49.67 %37.38 %Total Assets$12.2m
Current Liabilities 6.54 M
Accounts Payable 4.14 M
Short-Term Debt 138 K
Other Current Liabilities 2.26 M
Non-Current Liabilities 109 K
Long-Term Debt 109 K
Other Non-Current Liabilities 0
62.23 %34.06 %Total Liabilities$6.6m
EFFICIENCY
Earnings Waterfall Tiziana Life Sciences Ltd
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Revenue 0
Cost Of Revenue 0
Gross Profit 0
Operating Expenses 18 M
Operating Income -18 M
Other Expenses -742 K
Net Income -17.2 M
00(2m)(2m)(4m)(4m)(6m)(6m)(8m)(8m)(10m)(10m)(12m)(12m)(14m)(14m)(16m)(16m)(18m)(18m)000(18m)(18m)742k(17m)RevenueRevenueCost Of RevenueCost Of RevenueGross ProfitGross ProfitOperating ExpensesOperating ExpensesOperating IncomeOperating IncomeOther ExpensesOther ExpensesNet IncomeNet Income
RATIOS
0.00% GROSS MARGIN
0.00%
0.00% OPERATING MARGIN
0.00%
0.00% NET MARGIN
0.00%
-57.17% ROE
-57.17%
-36.98% ROA
-36.98%
-41.20% ROIC
-41.20%
FREE CASH FLOW ANALYSIS
Free Cash Flow Analysis Tiziana Life Sciences Ltd
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00(5m)(5m)(10m)(10m)(15m)(15m)(20m)(20m)(25m)(25m)20152015201620162017201720182018201920192020202020212021202220222023202320242024
Net Income -17.2 M
Depreciation & Amortization 96 K
Capital Expenditures 0
Stock-Based Compensation 1.73 M
Change in Working Capital -1.58 M
Others 1.24 M
Free Cash Flow -15.7 M
3. WALL STREET ANALYSTS ESTIMATES
Wall Street Analysts Price Targets Tiziana Life Sciences Ltd
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TLSA has no price targets from Wall Street.
4. DIVIDEND ANALYSIS
5. COMPETITION
slide 2 of 8
6. Ownership
Insider Ownership Tiziana Life Sciences Ltd
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Sold
0-3 MONTHS
0 USD 0
3-6 MONTHS
0 USD 0
6-9 MONTHS
0 USD 0
9-12 MONTHS
0 USD 0
Bought
0 USD 0
0-3 MONTHS
0 USD 0
3-6 MONTHS
0 USD 0
6-9 MONTHS
0 USD 0
9-12 MONTHS
7. News
Tiziana: Scope Of Foralumab Goes Beyond That Of Multiple Sclerosis Targeting Tiziana is developing foralumab, a fully human anti-CD3 monoclonal antibody, for non-active secondary progressive multiple sclerosis patients, with key data expected in 2026. A phase 2 trial of foralumab in early-stage Alzheimer's Disease is set to begin in 2025, targeting microglial activation and neuroinflammation. The global Alzheimer's Disease market is expected to reach $23.8 billion by 2031. seekingalpha.com - 3 weeks ago
Tiziana Life Sciences expands Phase 2 MS trial to fifth site, commences patient dosing Tiziana Life Sciences Ltd (NASDAQ:TLSA) announced that it has initiated patient dosing at the Weill Cornell Medicine Multiple Sclerosis Center in New York City as part of its ongoing Phase 2 clinical trial of intranasal foralumab in patients with non-active Secondary Progressive Multiple Sclerosis (na-SPMS). Weill Cornell marks the fifth site participating in the trial, joining Yale University, Johns Hopkins University, Brigham and Women's Hospital, and the University of Massachusetts. proactiveinvestors.com - 3 weeks ago
Tiziana Life Sciences Expands Phase 2 Clinical Trial of Intranasal Foralumab with Commencement of First Patient Dosing at Weill Cornell Multiple Sclerosis Center NEW YORK, June 13, 2025 (GLOBE NEWSWIRE) -- Tiziana Life Sciences, Ltd. (Nasdaq: TLSA) (“Tiziana” or the “Company”), a biotechnology company developing breakthrough immunomodulation therapies with its lead development candidate, intranasal foralumab, a fully human, anti-CD3 monoclonal antibody, today announces that dosing has commenced at the prestigious Weill Cornell Medicine Multiple Sclerosis Center in New York City, in its ongoing Phase 2 clinical trial evaluating intranasal foralumab in patients with non-active Secondary Progressive Multiple Sclerosis (na-SPMS). This fifth site complements existing sites at Yale University, Johns Hopkins University, Brigham and Women's Hospital, and the University of Massachusetts. globenewswire.com - 3 weeks ago
Tiziana Life Sciences to Present at the Bio International Convention NEW YORK, June 13, 2025 (GLOBE NEWSWIRE) -- Tiziana Life Sciences, Ltd. (Nasdaq: TLSA) (“Tiziana” or the “Company”), a biotechnology company developing breakthrough immunomodulation therapies with its lead development candidate, intranasal foralumab, a fully human, anti-CD3 monoclonal antibody, today announces that its CEO, Ivor Elrifi, will be giving an oral presentation during the Bio International Convention in Boston, MA. Mr Elrifi's presentation will cover the recent clinical findings of Tiziana's lead drug candidate, intranasal foralumab. Foralumab is the first fully human anti-CD3 monoclonal antibody administered via the intranasal route. This novel, non-systemic approach is designed to engage regulatory T cells, promoting immune tolerance while minimizing systemic immune suppression. Immunomodulation by intranasal foralumab represents a novel avenue for the treatment of neuroinflammatory and neurodegenerative human diseases. Tiziana has an ongoing Phase 2 trial in non-active Secondary Progressive Multiple Sclerosis and is progressing towards opening a Phase 2 trial in early Alzheimer's Disease. globenewswire.com - 3 weeks ago
Tiziana Life Sciences Announces Interview Highlighting Intranasal Foralumab for the Treatment of Moderate Alzheimer's Disease NEW YORK, May 23, 2025 (GLOBE NEWSWIRE) -- Tiziana Life Sciences, Ltd. (Nasdaq: TLSA) (“Tiziana” or the “Company”), a biotechnology company developing breakthrough immunomodulation therapies with its lead development candidate, intranasal foralumab, a fully human, anti-CD3 monoclonal antibody, today announced advancements in moderate Alzheimer's disease treatment, showcased in a recent feature on a national public radio station across the United States. The advancement involves the use of Tiziana's novel nasal spray, foralumab, which is designed to combat brain inflammation, marking a step forward in moderate Alzheimer's research and treatment. globenewswire.com - 1 month ago
Tiziana Life Sciences' foralumab reduced neuroinflammation in Alzheimer's patient, study shows Tiziana Life Sciences Ltd (NASDAQ:TLSA)' investigational therapy intranasal foralumab has been shown to significantly reduce neuroinflammation in a 78-year-old patient with moderate Alzheimer's disease (AD), a newly published study has shown. The study, published in the Journal of Clinical Nuclear Medicine, was led by Dr Tarun Singhal and Dr Howard Weiner of Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system. proactiveinvestors.com - 1 month ago
Tiziana Life Sciences Announces Purchase of Shares by Chairman NEW YORK, May 12, 2025 (GLOBE NEWSWIRE) -- Tiziana Life Sciences Ltd. (Nasdaq: TLSA) (“Tiziana” or the “Company”), a biotechnology company developing breakthrough immunomodulation therapies with its lead development candidate, intranasal foralumab, a fully human anti-CD3 monoclonal antibody, today announces that its Executive Chairman and Founder, Mr. globenewswire.com - 1 month ago
Tiziana Life Sciences reports reduced brain inflammation in Alzheimer's patient treated with nasal foralumab Tiziana Life Sciences Ltd (NASDAQ:TLSA) said on Friday that a patient with moderate Alzheimer's disease showed a marked reduction in brain inflammation after three months of treatment with its lead drug candidate, intranasal foralumab, under an expanded access program. A PET scan revealed a significant decrease in microglial activation—an indicator of neuroinflammation linked to Alzheimer's progression—according to data presented by Dr Howard Weiner at the 2025 AD/PD Conference in Vienna. proactiveinvestors.com - 1 month ago
Tiziana Life Sciences Announces Significant Reduction in Microglia Activation in PET Scan of Moderate Alzheimer's Patient Treated with Intranasal Foralumab NEW YORK, May 09, 2025 (GLOBE NEWSWIRE) -- Tiziana Life Sciences, Ltd. (Nasdaq: TLSA) (“Tiziana” or the “Company”), a biotechnology company developing breakthrough immunomodulation therapies with its lead development candidate, intranasal foralumab, a fully human anti-CD3 monoclonal antibody, today announced results of a PET scan showing a marked reduction in microglia activation associated with neuroinflammation in a patient suffering from moderate Alzheimer's disease (AD) who was treated for three months with intranasal foralumab under an expanded access program. The microglial TSPO PET scan revealed a significant decrease in microglia activation, a key indicator of neuroinflammation associated with Alzheimer's disease progression. globenewswire.com - 1 month ago
Tiziana shares surge 21% on promising multiple sclerosis data Tiziana Life Sciences Ltd (NASDAQ:TLSA) shares jumped 21% in early trading Tuesday after the company reported positive early-stage data for its experimental multiple sclerosis treatment, nasal foralumab. The open-label study involved 10 patients with non-active secondary progressive MS, a form of the disease where disability progresses despite the absence of relapses and few treatment options exist. proactiveinvestors.com - 2 months ago
Tiziana reports encouraging results for nasal MS drug in early study Tiziana Life Sciences Ltd (NASDAQ:TLSA) said Tuesday that its experimental multiple sclerosis therapy, nasal foralumab, showed positive results in an early-stage study, with patients experiencing stabilised disease progression and reduced signs of brain inflammation. The open-label study followed 10 patients with non-active secondary progressive multiple sclerosis, or na-SPMS, a difficult-to-treat form of the disease in which disability worsens even in the absence of relapses. proactiveinvestors.com - 2 months ago
Tiziana Life Sciences Announces Comprehensive Positive Results from Study of Nasal Foralumab in Patients with Multiple Sclerosis Meaningful Fatigue score reduction seen in study is a critically important quality of life (QoL) measure for Multiple Sclerosis patients. All patients experienced stabilization of Expanded Disability Status Scale (EDSS) scores. globenewswire.com - 2 months ago
8. Profile Summary

Tiziana Life Sciences Ltd TLSA

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COUNTRY GB
INDUSTRY Biotechnology
MARKET CAP $ 84.2 M
Dividend Yield 0.00%
Description Tiziana Life Sciences Ltd, a biotechnology company, focuses on the discovery and development of molecules to treat human diseases in oncology and immunology. The company's lead product candidate in immunology is Foralumab (TZLS-401), a human anti-CD3 monoclonal antibody (mAb) for the treatment of Crohn's, graft versus host, ulcerative colitis, multiple sclerosis, type-1 diabetes, inflammatory bowel, psoriasis, and rheumatoid arthritis diseases. It also develops Milciclib (TZLS-201), a small molecule inhibitor of various cyclin-dependent kinases, tropomycin receptor kinases, and Src family kinases controlling cell growth and malignant progression of cancer; and anti-Interleukin 6 receptor (IL6R) mAb (TZLS-501), a fully human monoclonal antibody for the treatment of IL6-induced inflammation and to treat COVID-19 patients. The company was incorporated in 1998 and is headquatered in London, the United Kingdom.
Contact 55 Park Lane, London, W1K 1NA https://www.tizianalifesciences.com
IPO Date Nov. 20, 2018
Employees 9
Officers Ms. Keeren Shah Chief Operating Officer & Chief Financial Officer Dr. William A. Clementi Ph.D., Pharm.D. Chief Development Officer Mr. Gabriele Marco Antonio Cerrone M.B.A. Founder & Executive Chairman Dr. Ivor R. Elrifi Ph.D. Chief Executive Officer & Executive Director Dr. Napoleone Ferrara M.D. Member of Scientific Advisory Board