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Healthcare - Biotechnology - NASDAQ - US
$ 1.76
15.1 %
$ 193 M
Market Cap
-1.66
P/E
1. INTRINSIC VALUE

This DCF valuation model was last updated on Apr, 22, 2025.

The intrinsic value of one ANNX stock under the worst case scenario is HIDDEN Compared to the current market price of 1.76 USD, Annexon, Inc. is HIDDEN

This DCF valuation model was last updated on Apr, 22, 2025.

The intrinsic value of one ANNX stock under the base case scenario is HIDDEN Compared to the current market price of 1.76 USD, Annexon, Inc. is HIDDEN

This DCF valuation model was last updated on Apr, 22, 2025.

The intrinsic value of one ANNX stock under the best case scenario is HIDDEN Compared to the current market price of 1.76 USD, Annexon, Inc. is HIDDEN

2. FUNDAMENTAL ANALYSIS

Price Chart ANNX

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$8.0$8.0$7.0$7.0$6.0$6.0$5.0$5.0$4.0$4.0$3.0$3.0$2.0$2.0$1.0$1.0Nov '24Nov '2415 Nov15 NovDec '24Dec '2415 Dec15 DecJan '25Jan '2515 Jan15 JanFeb '25Feb '2515 Feb15 FebMar '25Mar '2515 Mar15 MarApr '25Apr '2515 Apr15 Apr
FINANCIALS
0 REVENUE
0.00%
-154 M OPERATING INCOME
-7.20%
-138 M NET INCOME
-2.95%
-118 M OPERATING CASH FLOW
2.59%
-219 M INVESTING CASH FLOW
-309.46%
161 M FINANCING CASH FLOW
18.95%
0 REVENUE
0.00%
-52.5 M OPERATING INCOME
-33.05%
-48.6 M NET INCOME
-39.53%
-36 M OPERATING CASH FLOW
-12.49%
1.01 M INVESTING CASH FLOW
102.20%
4.97 M FINANCING CASH FLOW
2738.29%
Balance Sheet Annexon, Inc.
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Current Assets 316 M
Cash & Short-Term Investments 312 M
Receivables 0
Other Current Assets 4.44 M
Non-Current Assets 33.6 M
Long-Term Investments 0
PP&E 29.3 M
Other Non-Current Assets 4.27 M
89.13 %8.38 %Total Assets$350.1m
Current Liabilities 30.5 M
Accounts Payable 10.4 M
Short-Term Debt 2.52 M
Other Current Liabilities 17.6 M
Non-Current Liabilities 26.5 M
Long-Term Debt 26.5 M
Other Non-Current Liabilities 0
18.30 %4.42 %30.84 %46.44 %Total Liabilities$57.0m
EFFICIENCY
Earnings Waterfall Annexon, Inc.
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Revenue 0
Cost Of Revenue 0
Gross Profit 0
Operating Expenses 154 M
Operating Income -154 M
Other Expenses -15.9 M
Net Income -138 M
00(20m)(20m)(40m)(40m)(60m)(60m)(80m)(80m)(100m)(100m)(120m)(120m)(140m)(140m)(160m)(160m)000(154m)(154m)16m(138m)RevenueRevenueCost Of RevenueCost Of RevenueGross ProfitGross ProfitOperating ExpensesOperating ExpensesOperating IncomeOperating IncomeOther ExpensesOther ExpensesNet IncomeNet Income
RATIOS
0.00% GROSS MARGIN
0.00%
0.00% OPERATING MARGIN
0.00%
0.00% NET MARGIN
0.00%
-47.15% ROE
-47.15%
-39.48% ROA
-39.48%
-47.84% ROIC
-47.84%
FREE CASH FLOW ANALYSIS
Free Cash Flow Analysis Annexon, Inc.
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00(20m)(20m)(40m)(40m)(60m)(60m)(80m)(80m)(100m)(100m)(120m)(120m)(140m)(140m)2018201820192019202020202021202120222022202320232024202420252025
Net Income -138 M
Depreciation & Amortization 2.15 M
Capital Expenditures -15 K
Stock-Based Compensation 19.4 M
Change in Working Capital 6.36 M
Others -6.32 M
Free Cash Flow -118 M
3. WALL STREET ANALYSTS ESTIMATES
Wall Street Analysts Price Targets Annexon, Inc.
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Wall Street analysts predict an average 1-year price target for ANNX of $12 , with forecasts ranging from a low of $10 to a high of $14 .
ANNX Lowest Price Target Wall Street Target
10 USD 468.18%
ANNX Average Price Target Wall Street Target
12 USD 581.82%
ANNX Highest Price Target Wall Street Target
14 USD 695.45%
Price
Max Price Target
Min Price Target
Average Price Target
1414121210108866442200Jun '24Jun '24Jul '24Jul '24Aug '24Aug '24Oct '24Oct '24Nov '24Nov '2420252025Feb '25Feb '25Apr '25Apr '25Jun '25Jun '25Jul '25Jul '25Aug '25Aug '25Oct '25Oct '25Nov '25Nov '2520262026Feb '26Feb '26Apr '26Apr '26
4. DIVIDEND ANALYSIS
5. COMPETITION
slide 2 of 16
6. Ownership
Insider Ownership Annexon, Inc.
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Sold
0-3 MONTHS
126 K USD 6
3-6 MONTHS
0 USD 0
6-9 MONTHS
170 K USD 1
9-12 MONTHS
18 K USD 3
Bought
0 USD 0
0-3 MONTHS
17.1 K USD 1
3-6 MONTHS
56.6 K USD 1
6-9 MONTHS
46.4 K USD 1
9-12 MONTHS
7. News
Annexon Reports Inducement Grant to New Employee Under Nasdaq Listing Rule 5635(c)(4) BRISBANE, Calif., April 16, 2025 (GLOBE NEWSWIRE) -- Annexon, Inc. (Nasdaq: ANNX), a biopharmaceutical company advancing a late-stage clinical platform of novel therapies for people living with devastating classical complement-mediated neuroinflammatory diseases of the body, brain, and eye, today announced that it has granted inducement to a new non-executive employee under the terms of the 2022 Employment Inducement Award Plan. The equity award was approved on April 11, 2025, in accordance with Nasdaq Listing Rule 5635(c)(4). globenewswire.com - 2 weeks ago
Annexon: With IGOS Study Completion, Pre-BLA Meeting In 1st Half 2025 On Deck Annexon achieved primary endpoints in two Phase 3 studies for tanruprubart in treating Guillain-Barre Syndrome, setting the stage for a pre-BLA meeting with the FDA in H1 2025. The company has $312 million in cash, enough to fund operations into H2 2026, reducing the need for imminent fundraising. Annexon is also developing ANX007 for Geographic Atrophy, with key milestones including enrollment completion in H2 2025 and topline data in H2 2026. seekingalpha.com - 2 weeks ago
Annexon Highlights Pivotal Data on First Potential Targeted Therapy for Guillain-Barré Syndrome (GBS) and Showcases New GBS Education Campaign at American Academy of Neurology (AAN) 2025 Annual Meeting Oral Presentation Features Phase 3 Data Showing Rapid Recovery and Durable Benefit of Tanruprubart (formerly ANX005) on Clinically Meaningful Measures across Multiple Stages of GBS globenewswire.com - 3 weeks ago
Annexon Highlights Leadership in Advancing Clinical Research and Education for Guillain-Barré Syndrome (GBS) at American Academy of Neurology (AAN) 2025 Annual Meeting Oral Plenary Presentation on Tuesday, April 8 Features Phase 3 Data for ANX005, the First Potential Targeted Therapy for GBS, Showing Rapid and Durable Benefit Across Clinical Measures and Time Points globenewswire.com - 4 weeks ago
Annexon Reports Inducement Grant to New Employee Under Nasdaq Listing Rule 5635(c)(4) BRISBANE, Calif., March 17, 2025 (GLOBE NEWSWIRE) -- Annexon, Inc. (Nasdaq: ANNX), a biopharmaceutical company advancing a late-stage clinical platform of novel therapies for people living with devastating classical complement-mediated neuroinflammatory diseases of the body, brain, and eye, today announced that it has granted inducement to a new non-executive employee under the terms of the 2022 Employment Inducement Award Plan. The equity award was approved on March 12, 2025, in accordance with Nasdaq Listing Rule 5635(c)(4). globenewswire.com - 1 month ago
Annexon Reports Fourth Quarter and Year-End 2024 Financial Results, Portfolio Progress and Key Anticipated Milestones Robust, Consistent Phase 3 Data and Real-World Evidence Outcomes Support ANX005 as Potential First Targeted Therapy for GBS; Pre-BLA Meeting Targeted for 1H 2025 Ahead of Planned Biologics License Application (BLA) Submission Established Groundbreaking Global Registration Path for ANX007 to be Potential First Vision-Preserving Treatment for Dry AMD with GA in Europe and U.S.; Topline Phase 3 ARCHER II Data Expected Second Half 2026 First-in-Kind Oral C1s Inhibitor POC Trial Ongoing with Dosing in Three Patients with Cold Agglutin Disease; Expanded ANX1502 Dataset to Include Up to Seven Patients Expected Mid-2025 Strong Balance Sheet with Cash, Cash Equivalents, and Short-term Investments of Approximately $312 Million as of December 31, 2024, and Anticipated Runway into Second Half 2026 BRISBANE, Calif., March 03, 2025 (GLOBE NEWSWIRE) -- Annexon, Inc. (Nasdaq: ANNX), a biopharmaceutical company advancing a late-stage clinical platform of novel therapies for people living with devastating classical complement-mediated neuroinflammatory diseases of the body, brain, and eye, today highlighted portfolio progress and reported fourth quarter and full year 2024 financial results. globenewswire.com - 2 months ago
Annexon Biosciences to Present at the TD Cowen 45th Annual Health Care Conference BRISBANE, Calif., Feb. 26, 2025 (GLOBE NEWSWIRE) -- Annexon, Inc. (Nasdaq: ANNX), a biopharmaceutical company advancing a late-stage clinical platform of novel therapies for people living with devastating classical complement-mediated neuroinflammatory diseases of the body, brain, and eye, today announced that Douglas Love, president and chief executive officer, will present at the TD Cowen 45th Annual Health Care Conference on Tuesday, March 4, 2025 at 11:50 a.m. EST. globenewswire.com - 2 months ago
Annexon Reports Inducement Grants to New Employees Under Nasdaq Listing Rule 5635(c)(4) BRISBANE, Calif., Feb. 18, 2025 (GLOBE NEWSWIRE) -- Annexon, Inc. (Nasdaq: ANNX), a biopharmaceutical company advancing a late-stage clinical platform of novel therapies for people living with devastating classical complement-mediated neuroinflammatory diseases of the body, brain, and eye, today announced that it has granted inducement to six new non-executive employees under the terms of the 2022 Employment Inducement Award Plan. globenewswire.com - 2 months ago
Annexon Announces Presentations Highlighting ANX007 Functional and Structural Differentiation in Geographic Atrophy at the Macula Society 48th Annual Meeting BRISBANE, Calif., Feb. 13, 2025 (GLOBE NEWSWIRE) -- Annexon, Inc. (Nasdaq: ANNX), a biopharmaceutical company advancing a late-stage clinical platform of novel therapies for people living with devastating classical complement-mediated neuroinflammatory diseases of the body, brain, and eye, today announced presentations on ANX007 in geographic atrophy (GA) at the Macula Society 48th Annual Meeting being held February 12-15 in Charlotte Harbor, Florida. globenewswire.com - 2 months ago
Annexon Biosciences to Present at the 43rd Annual J.P. Morgan Healthcare Conference BRISBANE, Calif., Jan. 07, 2025 (GLOBE NEWSWIRE) -- Annexon, Inc. (Nasdaq: ANNX), a biopharmaceutical company advancing a late-stage clinical platform of novel therapies for people living with devastating classical complement-mediated neuroinflammatory diseases of the body, brain, and eye, today announced that Douglas Love, president and chief executive officer, will present at the 43ʳᵈ Annual J.P. Morgan Healthcare Conference on Tuesday, January 14, 2025 at 3:00 p.m. PST. globenewswire.com - 3 months ago
Annexon Reports Inducement Grants to New Employees Under Nasdaq Listing Rule 5635(c)(4) BRISBANE, Calif., Dec. 16, 2024 (GLOBE NEWSWIRE) -- Annexon, Inc. (Nasdaq: ANNX), a biopharmaceutical company advancing a late-stage clinical platform of novel therapies for people living with devastating classical complement-mediated neuroinflammatory diseases of the body, brain, and eye, today announced that it has granted inducement to nine new non-executive employees under the terms of the 2022 Employment Inducement Award Plan. The equity awards were approved on December 10, 2024, in accordance with Nasdaq Listing Rule 5635(c)(4). globenewswire.com - 4 months ago
Annexon Announces Positive Topline Results from Real-World Evidence Study Comparing ANX005 Treatment to Intravenous Immunoglobulin (IVIg) or Plasma Exchange (PE) in a Matched Patient Cohort for the Treatment of Guillain-Barré Syndrome (GBS) Real-World Evidence Study Strengthens the Body of Evidence Supporting ANX005 for Treatment of GBS ANX005 Phase 3 Population Was Matched 1:1 on Prespecified Criteria with Patients in International GBS Outcomes Study (IGOS) Matched Cohort Study Showed Early and Greater Benefits of ANX005 over IVIg or PE in Muscle Strength and Functional Outcomes Across Multiple Measurements Conference Call and Webcast Today at 8:30 a.m. ET BRISBANE, Calif. globenewswire.com - 4 months ago
8. Profile Summary

Annexon, Inc. ANNX

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COUNTRY US
INDUSTRY Biotechnology
MARKET CAP $ 193 M
Dividend Yield 0.00%
Description Annexon, Inc., a clinical-stage biopharmaceutical company, discovers and develops therapeutics for autoimmune, neurodegenerative, and ophthalmic disorders. The company's C1q is an initiating molecule of the classical complement pathway that targets distinct disease processes, such as antibody-mediated autoimmune disease and complement-mediated neurodegeneration. Its product candidates include ANX005, a monoclonal antibody, which is in Phase II/III clinical trials to treat patients with guillain- barré syndrome; Phase II trial in patients with warm autoimmune hemolytic anemia; and Phase II clinical trial for Huntington's disease and amyotrophic lateral sclerosis. The company is also developing ANX009 that is in Phase Ib trial in patients with lupus nephritis; and ANX007, which is in Phase II clinical trials to treat patients with geographic atrophy. In addition, it develops ANX105, an investigational monoclonal antibody targeting neurodegenerative indications; and ANX1502, an investigational oral small molecule for the treatment of certain autoimmune indications. The company was incorporated in 2011 and is headquartered in Brisbane, California.
Contact 1400 Sierra Point Parkway, Brisbane, CA, 94005 https://www.annexonbio.com
IPO Date July 24, 2020
Employees 100
Officers Mr. Henk-Andre Kroon M.D. Senior Vice President of Translational Medicine Dr. Ted Yednock Ph.D. Executive Vice President, Chief Innovation Officer & Chairman of the Scientific Advisory Board Dr. Jamie Dananberg M.D. Executive Vice President & Chief Medical Officer Mr. Shikhar Agarwal M.B.A. Senior Vice President & Head of Commercial Dr. Sunil Mehta Pharm.D. Senior Vice President of Medical Affairs Mr. Douglas Love Esq., J.D. Chief Executive Officer, President & Director Ms. Jennifer Lew CPA Executive Vice President, Chief Financial Officer & Corporate Secretary Mr. Michael Overdorf M.B.A. Executive Vice President & Chief Business Officer Dr. Dean R. Artis Ph.D. Chief Scientific Officer & Executive Vice President