image
Healthcare - Biotechnology - NASDAQ - US
$ 6.12
-3.32 %
$ 647 M
Market Cap
-5.06
P/E
1. INTRINSIC VALUE

Annexon, Inc., a clinical-stage biopharmaceutical company, discovers and develops therapeutics for autoimmune, neurodegenerative, and ophthalmic disorders. The company's C1q is an initiating molecule of the classical complement pathway that targets distinct disease processes, such as antibody-mediated autoimmune disease and complement-mediated neurodegeneration. Its product candidates include ANX005, a monoclonal antibody, which is in Phase II/III clinical trials to treat patients with guillain- barré syndrome; Phase II trial in patients with warm autoimmune hemolytic anemia; and Phase II clinical trial for Huntington's disease and amyotrophic lateral sclerosis. The company is also developing ANX009 that is in Phase Ib trial in patients with lupus nephritis; and ANX007, which is in Phase II clinical trials to treat patients with geographic atrophy.[ Read More ]

The intrinsic value of one ANNX stock under the base case scenario is HIDDEN Compared to the current market price of 6.12 USD, Annexon, Inc. is HIDDEN

2. FUNDAMENTAL ANALYSIS

Price Chart ANNX

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FINANCIALS
0 REVENUE
0.00%
-144 M OPERATING INCOME
1.29%
-134 M NET INCOME
5.43%
-121 M OPERATING CASH FLOW
-4.16%
70.7 M INVESTING CASH FLOW
20.98%
136 M FINANCING CASH FLOW
10.26%
0 REVENUE
0.00%
-39.4 M OPERATING INCOME
-17.46%
-34.8 M NET INCOME
-17.61%
-32 M OPERATING CASH FLOW
-47.47%
-45.9 M INVESTING CASH FLOW
52.45%
175 K FINANCING CASH FLOW
-99.86%
Balance Sheet Decomposition Annexon, Inc.
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Current Assets 264 M
Cash & Short-Term Investments 260 M
Receivables 0
Other Current Assets 4.14 M
Non-Current Assets 33.8 M
Long-Term Investments 0
PP&E 32.8 M
Other Non-Current Assets 1.03 M
Current Liabilities 17.9 M
Accounts Payable 5.49 M
Short-Term Debt 4.33 M
Other Current Liabilities 8.11 M
Non-Current Liabilities 29.2 M
Long-Term Debt 29.2 M
Other Non-Current Liabilities 0
EFFICIENCY
Earnings Waterfall Annexon, Inc.
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Revenue 0
Cost Of Revenue 3.27 M
Gross Profit -3.27 M
Operating Expenses 144 M
Operating Income -144 M
Other Expenses -9.49 M
Net Income -134 M
RATIOS
0.00% GROSS MARGIN
0.00%
0.00% OPERATING MARGIN
0.00%
0.00% NET MARGIN
0.00%
-53.58% ROE
-53.58%
-45.10% ROA
-45.10%
-56.87% ROIC
-56.87%
FREE CASH FLOW ANALYSIS
Free Cash Flow Analysis Annexon, Inc.
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Net Income -134 M
Depreciation & Amortization 2.15 M
Capital Expenditures -193 K
Stock-Based Compensation 18.2 M
Change in Working Capital -5.8 M
Others -5.16 M
Free Cash Flow -121 M
3. WALL STREET ANALYSTS ESTIMATES
Wall Street Analysts Price Targets Annexon, Inc.
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Wall Street analysts predict an average 1-year price target for ANNX of $12 , with forecasts ranging from a low of $10 to a high of $14 .
ANNX Lowest Price Target Wall Street Target
10 USD 63.40%
ANNX Average Price Target Wall Street Target
12 USD 96.08%
ANNX Highest Price Target Wall Street Target
14 USD 128.76%
4. DIVIDEND ANALYSIS
0.00% DIVIDEND YIELD
0 USD DIVIDEND PER SHARE
5. COMPETITION
6. Ownership
Insider Ownership Annexon, Inc.
image
Sold
0-3 MONTHS
170 K USD 1
3-6 MONTHS
18 K USD 3
6-9 MONTHS
39.4 K USD 3
9-12 MONTHS
249 K USD 4
Bought
36.6 K USD 1
0-3 MONTHS
51.4 K USD 1
3-6 MONTHS
34.4 K USD 1
6-9 MONTHS
1.01 M USD 1
9-12 MONTHS
Date Value Insider Amount Avg Price
1 month ago
Oct 15, 2024
Sell 40.1 K USD
Yednock Ted
EVP & CHIEF INNOVATION OFFICER
- 5408
7.41 USD
1 month ago
Oct 01, 2024
Bought 19.1 K USD
Carson William H.
Director
+ 3200
5.97 USD
1 month ago
Sep 19, 2024
Sell 32 K USD
Yednock Ted
EVP & CHIEF INNOVATION OFFICER
- 4500
7.1 USD
2 months ago
Sep 12, 2024
Sell 33.9 K USD
Yednock Ted
EVP & CHIEF INNOVATION OFFICER
- 5500
6.16 USD
2 months ago
Sep 05, 2024
Sell 31 K USD
Yednock Ted
EVP & CHIEF INNOVATION OFFICER
- 5500
5.64 USD
2 months ago
Sep 03, 2024
Bought 17.5 K USD
Carson William H.
Director
+ 3200
5.48 USD
2 months ago
Aug 29, 2024
Sell 32.7 K USD
Yednock Ted
EVP & CHIEF INNOVATION OFFICER
- 5500
5.95 USD
3 months ago
Aug 01, 2024
Bought 20 K USD
Carson William H.
Director
+ 3200
6.24 USD
4 months ago
Jul 15, 2024
Sell 4.72 K USD
Overdorf Michael
EVP & CHIEF BUSINESS OFFICER
- 784
6.02 USD
4 months ago
Jul 15, 2024
Sell 6.66 K USD
Lew Jennifer
EVP & CHIEF FINANCIAL OFFICER
- 1104
6.03 USD
4 months ago
Jul 15, 2024
Sell 6.66 K USD
Yednock Ted
EVP & CHIEF INNOVATION OFFICER
- 1106
6.02 USD
4 months ago
Jul 01, 2024
Bought 16 K USD
Carson William H.
Director
+ 3200
5 USD
5 months ago
Jun 03, 2024
Bought 15.5 K USD
Carson William H.
Director
+ 3200
4.831 USD
6 months ago
May 01, 2024
Bought 15 K USD
Carson William H.
Director
+ 3200
4.682 USD
7 months ago
Apr 08, 2024
Bought 19.4 K USD
Carson William H.
Director
+ 3200
6.066 USD
8 months ago
Feb 20, 2024
Sell 14.3 K USD
Lew Jennifer
EVP & CHIEF FINANCIAL OFFICER
- 2593
5.53 USD
8 months ago
Feb 20, 2024
Sell 14.3 K USD
Yednock Ted
EVP & CHIEF INNOVATION OFFICER
- 2604
5.51 USD
8 months ago
Feb 20, 2024
Sell 10.7 K USD
Overdorf Michael
EVP & CHIEF BUSINESS OFFICER
- 1951
5.48 USD
9 months ago
Feb 12, 2024
Sell 7.46 K USD
Overdorf Michael
EVP & CHIEF BUSINESS OFFICER
- 1349
5.53 USD
9 months ago
Feb 12, 2024
Sell 32 K USD
Love Douglas
PRESIDENT AND CEO
- 5782
5.54 USD
9 months ago
Feb 12, 2024
Sell 10 K USD
Lew Jennifer
EVP & CHIEF FINANCIAL OFFICER
- 1809
5.54 USD
9 months ago
Feb 12, 2024
Sell 10 K USD
Yednock Ted
EVP & CHIEF INNOVATION OFFICER
- 1810
5.54 USD
1 year ago
Jul 11, 2023
Sell 4.05 K USD
Yednock Ted
EVP & Chief Innovation Officer
- 1057
3.8361 USD
10 months ago
Dec 27, 2023
Sell 95 K USD
Yednock Ted
EVP & Chief Innovation Officer
- 21000
4.5222 USD
1 year ago
Jul 11, 2023
Sell 3.75 K USD
Overdorf Michael
EVP & Chief Business Officer
- 978
3.8361 USD
1 year ago
Jul 11, 2023
Sell 4.05 K USD
Lew Jennifer
EVP & Chief Financial Officer
- 1057
3.8361 USD
10 months ago
Dec 27, 2023
Sell 95 K USD
Yednock Ted
EVP & Chief Innovation Officer
- 21000
4.5222 USD
10 months ago
Dec 26, 2023
Bought 1.01 M USD
Satter Muneer A
director, 10 percent owner:
+ 350000
2.88 USD
1 year ago
May 25, 2023
Bought 640 K USD
Bain Capital Life Sciences Investors, LLC
10 percent owner
+ 300000
2.1324 USD
1 year ago
Feb 15, 2023
Sell 38.6 K USD
Love Douglas
President & CEO
- 6571
5.8688 USD
1 year ago
Feb 13, 2023
Sell 9.46 K USD
Overdorf Michael
EVP & Chief Business Officer
- 1501
6.3032 USD
1 year ago
Feb 14, 2023
Sell 907 USD
Overdorf Michael
EVP & Chief Business Officer
- 144
6.2993 USD
1 year ago
Feb 13, 2023
Sell 11 K USD
Lew Jennifer
EVP & Chief Financial Officer
- 1742
6.3081 USD
1 year ago
Feb 14, 2023
Sell 1.05 K USD
Lew Jennifer
EVP & Chief Financial Officer
- 166
6.303 USD
1 year ago
Feb 10, 2023
Bought 18 M USD
Satter Muneer A
director, 10 percent owner:
+ 2647058
6.8 USD
2 years ago
Jul 07, 2022
Bought 76.7 K USD
Satter Muneer A
director:
+ 613497
0.125 USD
2 years ago
Apr 14, 2022
Bought 147 K USD
Love Douglas
President & CEO
+ 60000
2.4469 USD
3 years ago
Sep 16, 2021
Sell 165 K USD
Love Douglas
President & CEO
- 7500
22.0454 USD
3 years ago
Sep 13, 2021
Sell 324 K USD
Yednock Ted
EVP & Chief Scientific Officer
- 16190
20.0037 USD
3 years ago
Sep 13, 2021
Sell 70 K USD
Lew Jennifer
EVP & Chief Financial Officer
- 3500
20.0096 USD
3 years ago
Jun 08, 2021
Sell 84.6 K USD
Love Douglas
President & CEO
- 3750
22.55 USD
3 years ago
Jun 07, 2021
Sell 83.7 K USD
Love Douglas
President & CEO
- 3750
22.3113 USD
3 years ago
Jun 03, 2021
Sell 275 K USD
Yednock Ted
EVP & Chief Scientific Officer
- 12816
21.4485 USD
3 years ago
Jun 03, 2021
Sell 47.4 K USD
Yednock Ted
EVP & Chief Scientific Officer
- 2184
21.722 USD
3 years ago
May 27, 2021
Sell 77.8 K USD
Lew Jennifer
EVP & Chief Financial Officer
- 3500
22.2386 USD
3 years ago
Apr 01, 2021
Sell 5.64 K USD
Love Douglas
President & CEO
- 200
28.19 USD
3 years ago
Apr 01, 2021
Sell 8.4 K USD
Love Douglas
President & CEO
- 300
28.01 USD
3 years ago
Mar 31, 2021
Sell 200 K USD
Love Douglas
President & CEO
- 7102
28.1077 USD
3 years ago
Mar 30, 2021
Sell 46.1 K USD
Love Douglas
President & CEO
- 1900
24.2711 USD
3 years ago
Mar 29, 2021
Sell 71.3 K USD
Love Douglas
President & CEO
- 2850
25.0216 USD
3 years ago
Mar 29, 2021
Sell 15.9 K USD
Love Douglas
President & CEO
- 600
26.4184 USD
3 years ago
Mar 29, 2021
Sell 8.17 K USD
Love Douglas
President & CEO
- 300
27.2383 USD
3 years ago
Mar 30, 2021
Sell 45.9 K USD
Love Douglas
President & CEO
- 1850
24.7843 USD
3 years ago
Mar 25, 2021
Sell 293 K USD
Yednock Ted
EVP & Chief Scientific Officer
- 10258
28.5392 USD
3 years ago
Mar 25, 2021
Sell 166 K USD
Yednock Ted
EVP & Chief Scientific Officer
- 5680
29.2102 USD
3 years ago
Mar 25, 2021
Sell 7.1 K USD
Yednock Ted
EVP & Chief Scientific Officer
- 237
29.96 USD
3 years ago
Mar 24, 2021
Sell 121 K USD
Keswani Sanjay
EVP & Chief Medical Officer
- 3995
30.1657 USD
3 years ago
Mar 23, 2021
Sell 38.5 K USD
Lew Jennifer
EVP & Chief Financial Officer
- 1400
27.5061 USD
3 years ago
Mar 23, 2021
Sell 51.2 K USD
Lew Jennifer
EVP & Chief Financial Officer
- 1800
28.4304 USD
3 years ago
Mar 23, 2021
Sell 52.5 K USD
Lew Jennifer
EVP & Chief Financial Officer
- 1800
29.1629 USD
4 years ago
Jul 28, 2020
Bought 3.4 M USD
Clarus Lifesciences III, L.P.
10 percent owner
+ 200000
17 USD
4 years ago
Jul 28, 2020
Bought 6.8 M USD
Bain Capital Life Sciences Investors, LLC
10 percent owner
+ 400000
17 USD
4 years ago
Jul 28, 2020
Bought 34 K USD
Lew Jennifer
EVP & Chief Financial Officer
+ 2000
17 USD
4 years ago
Jul 28, 2020
Bought 3.4 M USD
Satter Muneer A
Director
+ 200000
17 USD
4 years ago
Jul 28, 2020
Bought 5.95 M USD
Flynn James E
10 percent owner
+ 350000
17 USD
7. News
Annexon Reports Inducement Grants to New Employees Under Nasdaq Listing Rule 5635(c)(4) BRISBANE, Calif., Nov. 15, 2024 (GLOBE NEWSWIRE) -- Annexon, Inc. (Nasdaq: ANNX), a biopharmaceutical company advancing a late-stage clinical platform of novel therapies for people living with devastating classical complement-mediated neuroinflammatory diseases of the body, brain, and eye, today announced that it has granted inducement to seven new non-executive employees under the terms of the 2022 Employment Inducement Award Plan. The equity awards were approved on November 12, 2024, in accordance with Nasdaq Listing Rule 5635(c)(4). globenewswire.com - 1 day ago
Annexon Reports Third Quarter 2024 Portfolio and Financial Results, and Key Anticipated Milestones Topline Real-World Evidence (RWE) Comparability and Outcomes Data for ANX005 in Guillain-Barré Syndrome (GBS) Expected by Year-End 2024; Biologics License Application (BLA) Submission Targeted for First Half 2025 globenewswire.com - 2 days ago
Annexon Biosciences to Present at the Jefferies London Healthcare Conference BRISBANE, Calif., Nov. 13, 2024 (GLOBE NEWSWIRE) -- Annexon, Inc. (Nasdaq: ANNX), a biopharmaceutical company focused on upstream C1q to advance therapies for neuroinflammatory diseases of the body, brain and eye, today announced that Douglas Love, president and chief executive officer, will present at the Jefferies London Healthcare Conference on Wednesday, November 20, 2024 at 10:30 a.m. GMT. globenewswire.com - 3 days ago
Annexon Presents Phase 2 Vision Preservation Data with ANX007 in Dry AMD Patients with Less Advanced GA at the American Academy of Ophthalmology 2024 Meeting Enhanced protection of vision with ANX007 treatment in healthier eyes Greater preservation of EZ in the central fovea by ANX007 in patients with less advanced GA Pivotal Phase 3 ARCHER II Data Expected Second Half 2026 BRISBANE, Calif., Oct. 21, 2024 (GLOBE NEWSWIRE) -- Annexon, Inc. (Nasdaq: ANNX), a biopharmaceutical company focused on upstream C1q to advance therapies for neuroinflammatory diseases of the body, brain and eye, today announced new findings from its Phase 2 ARCHER study for ANX007 in geographic atrophy (GA) due to dry age-related macular degeneration (AMD). globenewswire.com - 3 weeks ago
Director William Carson Acquires 3,200 Shares of Annexon Inc (ANNX) On October 1, 2024, Director William Carson purchased 3,200 shares of Annexon Inc (ANNX, Financial), as reported in a recent SEC Filing. The transaction occurred at a price of $5.97 per share, totaling $19,104. gurufocus.com - 1 month ago
Speculative "Buy" Rating On Annexon: Evaluating The Potential Of ANX005 For GBS Annexon's ANX005 shows promise for GBS. Phase 3 trial results indicate expedited recovery and durable benefits. ANNX targets the classical complement pathway, specifically the C1q protein, to address autoimmune, neurodegenerative, and ophthalmic conditions. The company's pipeline includes ANX005, ANX007, and ANX1502. Due to its advanced development stage, ANX005 is the primary value driver. seekingalpha.com - 3 months ago
Annexon Reports Inducement Grants to New Employees Under Nasdaq Listing Rule 5635(c)(4) BRISBANE, Calif., Aug. 16, 2024 (GLOBE NEWSWIRE) -- Annexon, Inc. (Nasdaq: ANNX), a biopharmaceutical company advancing novel complement therapies for neuroinflammatory diseases of the body, brain and eye, today announced that it has granted inducement to two new non-executive employees under the terms of the 2022 Employment Inducement Award Plan. The equity awards were approved on August 15, 2024, in accordance with Nasdaq Listing Rule 5635(c)(4). globenewswire.com - 3 months ago
Annexon Reports Inducement Grant to New Employee Under Nasdaq Listing Rule 5635(c)(4) BRISBANE, Calif., July 16, 2024 (GLOBE NEWSWIRE) -- Annexon, Inc. (Nasdaq: ANNX), a biopharmaceutical company advancing novel therapies for neuroinflammatory diseases of the body, brain, and eye, today announced that it has granted inducement to a new non-executive employee under the terms of the 2022 Employment Inducement Award Plan. The equity award was approved on July 11, 2024, in accordance with Nasdaq Listing Rule 5635(c)(4). globenewswire.com - 4 months ago
Annexon to Present Additional Phase 2 Data Showing Preservation of Visual Function and Structure by ANX007 in Geographic Atrophy at the 42nd ASRS Annual Scientific Meeting Protective Effects of ANX007 on Visual Acuity and Vision Related Anatomical Measures in the Central Macula Will be Presented as a Late-Breaking Oral Presentation globenewswire.com - 4 months ago
Are Medical Stocks Lagging Annexon (ANNX) This Year? Here is how Annexon, Inc. (ANNX) and CareCloud, Inc. (CCLD) have performed compared to their sector so far this year. zacks.com - 4 months ago
Here's Why Annexon (ANNX) Is a Great 'Buy the Bottom' Stock Now After losing some value lately, a hammer chart pattern has been formed for Annexon (ANNX), indicating that the stock has found support. This, combined with an upward trend in earnings estimate revisions, could lead to a trend reversal for the stock in the near term. zacks.com - 4 months ago
Annexon Presented Additional Positive Phase 3 Results for ANX005 C1q-Targeted Immunotherapy in Guillain-Barré Syndrome at the 2024 PNS Annual Meeting ANX005-Treated Patients Demonstrated Faster and More Complete Recovery from Week 1 through Week 26 on Primary and Multiple Pre-Specified Endpoints globenewswire.com - 4 months ago
8. Profile Summary

Annexon, Inc. ANNX

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COUNTRY US
INDUSTRY Biotechnology
MARKET CAP $ 647 M
Dividend Yield 0.00%
Description Annexon, Inc., a clinical-stage biopharmaceutical company, discovers and develops therapeutics for autoimmune, neurodegenerative, and ophthalmic disorders. The company's C1q is an initiating molecule of the classical complement pathway that targets distinct disease processes, such as antibody-mediated autoimmune disease and complement-mediated neurodegeneration. Its product candidates include ANX005, a monoclonal antibody, which is in Phase II/III clinical trials to treat patients with guillain- barré syndrome; Phase II trial in patients with warm autoimmune hemolytic anemia; and Phase II clinical trial for Huntington's disease and amyotrophic lateral sclerosis. The company is also developing ANX009 that is in Phase Ib trial in patients with lupus nephritis; and ANX007, which is in Phase II clinical trials to treat patients with geographic atrophy. In addition, it develops ANX105, an investigational monoclonal antibody targeting neurodegenerative indications; and ANX1502, an investigational oral small molecule for the treatment of certain autoimmune indications. The company was incorporated in 2011 and is headquartered in Brisbane, California.
Contact 1400 Sierra Point Parkway, Brisbane, CA, 94005 https://www.annexonbio.com
IPO Date July 24, 2020
Employees 71
Officers Mr. Michael Overdorf M.B.A. Executive Vice President & Chief Business Officer Mr. Henk-Andre Kroon M.D. Senior Vice President of Translational Medicine Mr. Shikhar Agarwal M.B.A. Senior Vice President & Head of Commercial Dr. Sunil Mehta Pharm.D. Senior Vice President of Medical Affairs Mr. Douglas Love Esq., J.D. Chief Executive Officer, President & Director Dr. Dean R. Artis Ph.D. Chief Scientific Officer & Executive Vice President Dr. Jamie Dananberg M.D. Executive Vice President & Chief Medical Officer Dr. Ted Yednock Ph.D. Executive Vice President, Chief Innovation Officer & Chairman of the Scientific Advisory Board