Arcus Biosciences, Inc.

Arcus Biosciences, Inc.

RCUSยทNYSE

$23.86

-7.1%
HealthcareBiotechnology

Arcus Biosciences, Inc., a clinical-stage biopharmaceutical company, develops and commercializes cancer therapies in the United States. Its product pipeline includes, Etrumadenant, a dual A2a/A2b adenosine receptor antagonist, which is in a Phase 1b/2 clinical trial; and Zimberelimab, an anti-PD-1 antibody that is in Phase 1b clinical trial for monotherapy. The company also develops Domvanalimab, an anti-TIGIT monoclonal antibody, which is in Phase 2 development for the treatment of first-line metastatic non-small cell lung cancer in combination with Zimberelimab; Quemliclustat, a small-molecule CD73 inhibitor is in a Phase 1/1b study for the treatment of first-line metastatic pancreatic cancer; and AB521, an oral and small molecule HIF-2a inhibitor that is in Phase 1 study for the treatment of patients with von Hippel- Lindau disease. It has a clinical development collaboration agreement with Strata Oncology, Inc. to evaluate Zimberelimab; a collaboration with AstraZeneca, BVF Partners L.P to evaluate domvanalimab, its investigational anti-TIGIT antibody, in combination with Imfinzi (durvalumab) in a registrational Phase 3 clinical trial in patients with unresectable Stage III non-small cell lung cancer; and license agreements with Taiho Pharmaceutical Co., Ltd, Abmuno Therapeutics LLC, and WuXi Biologics to develop anti-CD39 antibody for the treatment of cancer. The company was incorporated in 2015 and is headquartered in Hayward, California.

At a Glance

Live Snapshot
Market Cap$2.40B
EPS-3.2900
P/E Ratio-7.25
Earnings Date08/05/2026
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Arcus Biosciences, Inc. Street Expectations Map

RCUS ยท NYSE

Wall Street analysts project that RCUS stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 31.17, with estimates ranging from a low of 22.00 to a high of 47.00.

Lowest Target
22.00
-7.80%
Consensus Target
31.17
30.64%
Highest Target
47.00
96.98%

The consensus 1-year price target stands at 31.17, with estimates ranging from a low of 22.00 to a high of 47.00.

Analyst Consensus Analysis

Upside Potential

+30.6%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

80.2% spread

High uncertainty. Very wide target spread indicates significant disagreement among analystsโ€”major valuation uncertainty or transformation underway.

Risk-Reward Profile

12.44x

Favorable risk-reward. Potential upside significantly exceeds downside risk, offering asymmetric return profile attractive for risk-tolerant investors.

Analyst Conviction

Low

High uncertainty: Wide dispersion indicates analysts struggle to agree on valuationโ€”proceed with caution and independent analysis.

Market Sentiment Insight

High risk, high reward: Substantial upside potential exists, but wide analyst disagreement signals execution risk or unclear catalysts. Thorough due diligence essential before committing capital.

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Arcus Biosciences, Inc. Forward Estimates of Revenue

RCUS ยท NYSE
Latest Revenue
247.00M
FY 2025
Avg Estimate
129.91M
FY 2026
Estimate Range
71.64M - 193.44M
Analyst Spread

Forward Growth Analysis

Projected Growth-47.4%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage8 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread94%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

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Arcus Biosciences, Inc. Forward Estimates of Net Income

RCUS ยท NYSE
Latest Net Income
-353.00M
FY 2025
Avg Estimate
-368.53M
FY 2026
Estimate Range
-444.81M - -292.25M
Analyst Spread

Forward Growth Analysis

Projected Growth-4.4%

Declining expectations indicate headwindsโ€”investigate whether temporary or structural issues.

Analyst Coverage8 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread41%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

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Arcus Biosciences, Inc. Forward Estimates of EPS

RCUS ยท NYSE
Latest EPS
-3.29
FY 2025
Avg Estimate
$-3.98
FY 2026
Estimate Range
$-4.94 - $-3.24
Analyst Spread

Forward Growth Analysis

Projected Growth-20.9%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage6 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread43%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

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Arcus Biosciences, Inc. Forward Estimates of EBIT

RCUS ยท NYSE
Latest EBIT
-345.00M
FY 2025
Avg Estimate
-100.19M
FY 2026
Estimate Range
-149.19M - -55.26M
Analyst Spread

Forward Growth Analysis

Projected Growth+71.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage8 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread94%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

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Arcus Biosciences, Inc. Forward Estimates of EBITDA

RCUS ยท NYSE
Latest EBITDA
-335.00M
FY 2025
Avg Estimate
-99.92M
FY 2026
Estimate Range
-148.79M - -55.11M
Analyst Spread

Forward Growth Analysis

Projected Growth+70.2%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage8 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread94%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

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Arcus Biosciences, Inc. Forward Estimates of SG&A Expense

RCUS ยท NYSE
Latest SG&A Expense
110.00M
FY 2025
Avg Estimate
81.40M
FY 2026
Estimate Range
44.89M - 121.21M
Analyst Spread

Forward Growth Analysis

Projected Growth-26.0%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage8 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread94%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

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Arcus Biosciences, Inc. Insider Positioning

RCUS ยท NYSE

During the last 12 months, insiders have sold $9.42M worth of RCUS shares, with no buying activity reported.

3 Months

Bought

0

0.00

Sold

10.3K

264.99K

Net Activity

-265K

-$265K

3-6 Months

Bought

0

0.00

Sold

172.3K

3.77M

Net Activity

-3.8M

-$3.77M

6-9 Months

Bought

0

0.00

Sold

248.3K

5.38M

Net Activity

-5.4M

-$5.38M

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

No buying activity

Top Sellers

1
JJC

Jaen Juan C.

Officer: President

242.0K sharesโ€ข8 transactions

$5.35M

2
JJ

Jarrett Jennifer

Officer: Chief Operating Officer

71.5K sharesโ€ข3 transactions

$1.42M

3
RTJ

Rosen Terry J

Director, Officer: Chief Executive Officer

54.7K sharesโ€ข2 transactions

$1.20M

4
GIRC

Goeltz Ii Robert C.

Officer: Chief Financial Officer

25.4K sharesโ€ข4 transactions

$603K

5
TCC

Tang Carolyn C.

Officer: General Counsel

14.5K sharesโ€ข2 transactions

$318K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $9.42M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$265K

Heavy recent selling activity. Recent insider sales notably exceed purchasesโ€”may warrant investigation into company developments.

Insider Participation

High Selling

5 insider sellers vs. 0 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.