Charles River Laboratories International, Inc.

Charles River Laboratories International, Inc.

CRLยทNYSE

$179.87

+4.2%
HealthcareMedical - Diagnostics & Research

Charles River Laboratories International, Inc., a non-clinical contract research organization, provides drug discovery, non-clinical development, and safety testing services in the United States, Europe, Canada, the Asia Pacific, and internationally. It operates through three segments: Research Models and Services (RMS), Discovery and Safety Assessment (DSA), and Manufacturing Solutions (Manufacturing). The RMS segment produces and sells rodent research model strains and purpose-bred rats and mice for use by researchers. This segment also provides a range of services to assist its clients in supporting the use of research models in research and screening non-clinical drug candidates, including research models, genetically engineered models and services, insourcing solutions, and research animal diagnostic services. The DSA segment offers early and in vivo discovery services for the identification and validation of novel targets, chemical compounds, and antibodies through delivery of non-clinical drug and therapeutic candidates ready for safety assessment; and safety assessment services, such as toxicology, pathology, safety pharmacology, bioanalysis, drug metabolism, and pharmacokinetics services. The Manufacturing segment provides in vitro methods for conventional and rapid quality control testing of sterile and non-sterile pharmaceuticals and consumer products. This segment also offers specialized testing of biologics that are outsourced by pharmaceutical and biotechnology companies; and avian vaccine services that provide specific-pathogen-free (SPF) fertile chicken eggs, SPF chickens, and diagnostic products used to manufacture vaccines. The company also provides contract vivarium operation services to biopharmaceutical clients. Charles River Laboratories International, Inc. was founded in 1947 and is headquartered in Wilmington, Massachusetts.

At a Glance

Live Snapshot
Market Cap$8.66B
EPS-2.9100
P/E Ratio-61.81
Earnings Date08/05/2026

Intrinsic Alpha Methodology

Thesis Lenses

Signal ยท Driver ยท Risk

Signal

Medium confidence

Valuation multiple is compressed (P/E -61.8).

Valuation inputs: P/E -61.8, earnings yield N/A, momentum +4.2%.

If multiples stay elevated while momentum fades, downside repricing risk rises.

Driver

High confidence

Return profile is soft (ROE -4.6%, ROIC +8.4%).

Profitability stack: net margin -3.6%, ROE -4.6%, ROIC +8.4%.

Quality deterioration often appears in margins before it shows up in headline EPS.

Risk

High confidence

Risk profile is balanced but has notable pressure points to monitor.

Risk factors: liabilities/assets +55.0%, momentum +4.2%, net margin -3.6%.

Higher leverage with weak momentum and thin margins can amplify drawdown severity.

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Charles River Laboratories International, Inc. Market vs Earnings Trajectory

CRL ยท NYSE

Loading price and EPS data...

Charles River Laboratories International, Inc.

Charles River Laboratories International, Inc. Fair Value Envelope

CRL ยท NYSE

Our analysis suggests that CRL has a fair value of HIDDEN per share in the Base Case projection. With shares currently trading at $179.87, this represents a potential HIDDEN relative to our calculated worth for Charles River Laboratories International, Inc..

Intrinsic Value
Current Price: $179.87
3Y-130.0%
5Y-140.0%
10Y-188.0%
3Y+1.0%
5Y+37.0%
10Y+139.0%
3Y-130.0%
5Y-140.0%
10Y-193.0%
3Y+19.0%
5Y+35.0%
10Y+147.0%
3Y+76.0%
5Y+36.0%
10Y+113.0%
3Y-6.0%
5Y+30.0%
10Y+163.0%
Charles River Laboratories International, Inc.

Charles River Laboratories International, Inc. Profit Bridge

CRL ยท NYSE
Revenue4.02B
Cost of Goods Sold (2.79B)
Gross Profit1.23B
Operating Expenses (717.73M)
Operating Income507.84M
Interest Expense (107.03M)
Other Income/Expense-607.34M
Pretax Income-99.50M
Income Tax (42.66M)
Net Income-144.34M
Net Income
-144.34M

Profitability Analysis

Gross Margin

30.5%

Moderate margins typical of competitive industries. Monitor for pricing pressure or rising costs.

Operating Margin

12.6%

Acceptable margins but limited operational leverage. Operating expense control is important.

Net Profit Margin

-3.6%

Net losses indicate the company is burning cash. Sustainability depends on path to profitability.

Profitability Insight

Non-operating losses: Core business is profitable but other expenses (interest, taxes, one-time items) are driving net losses. Review capital structure and non-operating items.

30.52%
Gross Profit Margin
-7%
3Y-16.0%
5Y-19.0%
10Y-19.0%
12.65%
Operating Profit Margin
125%
3Y-15.0%
5Y-24.0%
10Y-19.0%
-3.59%
Net Profit Margin
-1514%
3Y-131.0%
5Y-133.0%
10Y-154.0%
-4.56%
Return on Equity
-1633%
3Y-135.0%
5Y-130.0%
10Y-139.0%
-2.02%
Return on Assets
-1579%
3Y-135.0%
5Y-136.0%
10Y-148.0%
8.36%
Return on Invested Capital
784%
3Y+17.0%
5Y+3.0%
10Y+71.0%
CRL

Charles River Laboratories International, Inc. Cash Conversion Engine

CRL ยท NYSE
Net Income-142.16M
Depreciation & Amortization403.31M
Stock-Based Compensation71.08M
Change in Working Capital14.08M
Others466.62M
Capital Expenditures-219.15M
Free Cash Flow518.49M

Cash Flow Quality Analysis

FCF Conversion Rate

-364.7%

Negative free cash flow despite positive earnings raises concerns about cash generation ability or heavy capital requirements.

CapEx Intensity

29.7%

Moderate capital requirements typical of many stable businesses. Healthy balance between reinvestment and cash generation.

FCF Growth Trend

+3.4%

Flat FCF growth. Stable but not expandingโ€”monitor for signs of business maturity or temporary headwinds.

Working Capital Impact

+$14.08M

Working capital inflow boosted cash flow. Efficient management of receivables, inventory, and payables contributing positively.

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Charles River Laboratories International, Inc. Funding & Solvency Profile

CRL ยท NYSE
Cash & Cash Equivalents191.83M
Net Receivables700.25M
Inventory359.72M
Other Current Assets237.00M
Total Current Assets1 B
Property, Plant & Equipment1.83B
Goodwill & Intangible Assets3.29B
Long-Term Investments209.72M
Other Non-Current Assets826.16M
Total Non-Current Assets3 B
Total Assets
7.73B

Financial Health Analysis

Current Ratio

1.36x

Acceptable liquidity, but monitor closely. Current assets just barely cover current liabilities.

Debt-to-Equity Ratio

1.59x

Elevated leverage. Debt exceeds equity, which amplifies both gains and risks. Monitor debt servicing ability.

Working Capital

395 M

Positive working capital, but relatively tight. The company should monitor cash flow carefully.

Asset Composition

19% Current

Capital-intensive business with significant long-term investments in property, equipment, or intangibles.

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Charles River Laboratories International, Inc. Street Expectations Map

CRL ยท NYSE

Wall Street analysts project that CRL stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 213.17, with estimates ranging from a low of 192.00 to a high of 220.00.

Lowest Target
192.00
6.74%
Consensus Target
213.17
18.51%
Highest Target
220.00
22.31%

The consensus 1-year price target stands at 213.17, with estimates ranging from a low of 192.00 to a high of 220.00.

Analyst Consensus Analysis

Upside Potential

+18.5%

Strong upside potential. Consensus indicates attractive return opportunity with favorable risk-reward profile.

Analyst Agreement

13.1% spread

High analyst agreement. Narrow target range indicates strong consensus on valuation, suggesting clear investment thesis and predictable outlook.

Analyst Conviction

Very High

Strong buy conviction: High upside with tight consensus suggests compelling investment opportunity backed by analyst confidence.

Market Sentiment Insight

Monitor and evaluate: Current analyst consensus suggests limited conviction or near-term catalysts. Stay informed on company developments and reassess positioning as new information emerges.

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Charles River Laboratories International, Inc. Insider Positioning

CRL ยท NYSE

During the last 12 months, insiders have purchased $4K and sold $252K worth of CRL shares, resulting in $247K of net selling activity.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

25

4.36K

Sold

0

0.00

Net Activity

+4K

+$4K

6-9 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

9-12 Months

Bought

0

0.00

Sold

1.6K

251.58K

Net Activity

-252K

-$252K

Top Buyers

1
LJW

Laplume Joseph W

Officer: Evp, Corp Strategy & Develop

25 sharesโ€ข1 transactions

$4K

Top Sellers

1
LJW

Laplume Joseph W

Officer: Evp, Corp Strategy & Develop

1.6K sharesโ€ข3 transactions

$252K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $247K net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.02:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Insider Participation

Balanced

1 insider buyers and 1 sellers. Equal participation suggests mixed or neutral insider views.

No Dividend Yield Data

CRL has not reported any dividend yield values in the available annual periods.

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crl Dividend History

CRL
10Y CAGR +0%
Latest $0
Annual $0
Stable dividend payments
Last Period: +0%