Zenas BioPharma, Inc.

Zenas BioPharma, Inc.

ZBIOยทNASDAQ

$17.13

+1.6%
HealthcareBiotechnology

Zenas BioPharma, Inc., a clinical-stage biopharmaceutical company, engages in the development and commercialization of transformative immunology-based therapies. Its lead product candidate is obexelimab, a bifunctional monoclonal antibody for various indications, including immunoglobulin G4-related disease, multiple sclerosis, systemic lupus erythematosus, and warm autoimmune hemolytic anemia. The company also develops ZB002, an anti-TNFa monoclonal antibody; ZB004, a cytotoxic T-lymphocyte-associated antigen 4-immunoglobulin fusion; ZB001, an anti-insulin-like growth factor-1 receptor monoclonal antibody; and ZB005, an anti-active complement component 1s monoclonal antibody. Zenas BioPharma, Inc. was formerly known as Zenas BioPharma (Cayman) Limited and changed its name to Zenas BioPharma, Inc. in August 2023. The company was incorporated in 2019 and is based in Waltham, Massachusetts.

At a Glance

Live Snapshot
Market Cap$764.73M
EPS-8.4400
P/E Ratio-4.30
Earnings Date08/11/2026
zbio

Zenas BioPharma, Inc. Street Expectations Map

ZBIO ยท NASDAQ

Wall Street analysts project that ZBIO stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 35.00, with estimates ranging from a low of 22.00 to a high of 48.00.

Lowest Target
22.00
28.43%
Consensus Target
35.00
104.32%
Highest Target
48.00
180.21%

The consensus 1-year price target stands at 35.00, with estimates ranging from a low of 22.00 to a high of 48.00.

Analyst Consensus Analysis

Upside Potential

+104.3%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

74.3% spread

High uncertainty. Very wide target spread indicates significant disagreement among analystsโ€”major valuation uncertainty or transformation underway.

Analyst Conviction

Low

High uncertainty: Wide dispersion indicates analysts struggle to agree on valuationโ€”proceed with caution and independent analysis.

Market Sentiment Insight

High risk, high reward: Substantial upside potential exists, but wide analyst disagreement signals execution risk or unclear catalysts. Thorough due diligence essential before committing capital.

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Zenas BioPharma, Inc. Forward Estimates of Revenue

ZBIO ยท NASDAQ
Latest Revenue
10.00M
FY 2025
Avg Estimate
21.26M
FY 2026
Estimate Range
14.64M - 32.94M
Analyst Spread

Forward Growth Analysis

Projected Growth+112.6%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread86%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

zbio

Zenas BioPharma, Inc. Forward Estimates of Net Income

ZBIO ยท NASDAQ
Latest Net Income
-377.74M
FY 2025
Avg Estimate
-179.52M
FY 2026
Estimate Range
-212.64M - -146.40M
Analyst Spread

Forward Growth Analysis

Projected Growth+52.5%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread37%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

zbio

Zenas BioPharma, Inc. Forward Estimates of EPS

ZBIO ยท NASDAQ
Latest EPS
-8.44
FY 2025
Avg Estimate
$-4.26
FY 2026
Estimate Range
$-5.09 - $-3.50
Analyst Spread

Forward Growth Analysis

Projected Growth+49.5%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread37%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Zenas BioPharma, Inc. Forward Estimates of EBIT

ZBIO ยท NASDAQ
Latest EBIT
-211.38M
FY 2025
Avg Estimate
-3.85M
FY 2026
Estimate Range
-5.96M - -2.65M
Analyst Spread

Forward Growth Analysis

Projected Growth+98.2%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread86%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

zbio

Zenas BioPharma, Inc. Forward Estimates of EBITDA

ZBIO ยท NASDAQ
Latest EBITDA
-211.33M
FY 2025
Avg Estimate
-3.83M
FY 2026
Estimate Range
-5.94M - -2.64M
Analyst Spread

Forward Growth Analysis

Projected Growth+98.2%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread86%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Zenas BioPharma, Inc. Forward Estimates of SG&A Expense

ZBIO ยท NASDAQ
Latest SG&A Expense
53.32M
FY 2025
Avg Estimate
51.68M
FY 2026
Estimate Range
35.58M - 80.06M
Analyst Spread

Forward Growth Analysis

Projected Growth-3.1%

Declining expectations indicate headwindsโ€”investigate whether temporary or structural issues.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread86%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

zbio

Zenas BioPharma, Inc. Insider Positioning

ZBIO ยท NASDAQ

During the last 12 months, insiders have purchased $13.56M worth of ZBIO shares, with no selling activity reported.

3 Months

Bought

402.8K

7.67M

Sold

0

0.00

Net Activity

+7.7M

+$7.67M

3-6 Months

Bought

192.1K

3.49M

Sold

0

0.00

Net Activity

+3.5M

+$3.49M

6-9 Months

Bought

126.3K

2.40M

Sold

0

0.00

Net Activity

+2.4M

+$2.40M

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

1
MLOJ

Moulder Leon O Jr

Director, Officer: Chief Executive Officer

331.0K sharesโ€ข9 transactions

$5.76M

2
FFML

Fairmount Funds Management Llc

Director

150.0K sharesโ€ข1 transactions

$3.00M

3
LH

Lu Hongbo

Director

104.8K sharesโ€ข3 transactions

$2.15M

4
NJR

Nunn Jason Raleigh

Director

63.2K sharesโ€ข1 transactions

$1.20M

5
SOCML

Sr One Capital Management, Llc

10 Percent Owner

63.2K sharesโ€ข1 transactions

$1.20M

Top Sellers

No selling activity

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $13.56M net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

โˆž:1

Perfect buy/sell ratio. Only buying activity with zero sellingโ€”the most bullish possible insider signal.

Recent Trend (3 Months)

$7.67M

Very strong recent buying momentum. Recent insider purchases significantly outpace sales, suggesting near-term optimism.

Insider Participation

High Buying

5 insider buyers vs. 0 sellers. Broad-based buying across management team suggests widespread confidence.

Insider Activity Insight

Strong confluence of bullish signals: High buy/sell ratio, multiple insiders participating, and recent buying momentum all point to significant insider confidence. This level of coordinated buying often precedes positive developments.