X4 Pharmaceuticals, Inc.

X4 Pharmaceuticals, Inc.

XFOR·NASDAQ

$4.01

-0.74%
HealthcareBiotechnology

X4 Pharmaceuticals, Inc., a late-stage clinical biopharmaceutical company, focuses on the research, development, and commercialization of novel therapeutics for the treatment of rare diseases. Its lead product candidate is mavorixafor, a small molecule inhibitor of the chemokine receptor C-X-C chemokine receptor type 4 (CXCR4), which is in Phase III clinical trial for the treatment of patients with warts, hypogammaglobulinemia, infections, and myelokathexis syndrome; and Phase Ib clinical trial to treat chronic neutropenia and Waldenström macroglobulinemia. The company is also developing X4P-002, a CXCR4 antagonist for the treatment of brain cancers; and X4P-003, a CXCR4 antagonist for the treatment of CXCR4 disorders and primary immunodeficiencies. It has a license agreement with Abbisko Therapeutics Co., Ltd. to develop, manufacture, and commercialize mavorixafor in combination with checkpoint inhibitors or other agents in oncology indications. The company was founded in 2010 and is headquartered in Boston, Massachusetts.

At a Glance

Live Snapshot
Market Cap$378.22M
EPS-1.8700
P/E Ratio-2.14
Earnings Date08/06/2026
3Y-
5Y+1070.0%
10Y-
3Y-16.0%
5Y+27.0%
10Y+245.0%
3Y+11.0%
5Y+46.0%
10Y+296.0%
X4 Pharmaceuticals, Inc.

X4 Pharmaceuticals, Inc. Profit Bridge

XFOR · NASDAQ
Revenue35.11M
Cost of Goods Sold (6.26M)
Gross Profit28.86M
Operating Expenses (116.24M)
Operating Income-86.88M
Interest Expense (8.88M)
Other Income/Expense7.72M
Pretax Income-79.16M
Income Tax (41.00K)
Net Income-79.20M
Net Income
-79.20M

Profitability Analysis

Gross Margin

82.2%

Exceptional pricing power and cost management. The company retains over half of revenue after direct costs.

Operating Margin

-247.4%

Operating losses indicate the core business is unprofitable. Requires restructuring or revenue growth.

Net Profit Margin

-225.6%

Net losses indicate the company is burning cash. Sustainability depends on path to profitability.

Profitability Insight

Margin squeeze alert: Healthy gross margins but weak operating margins suggest excessive operating expenses. Cost optimization could unlock significant value.

X4 Pharmaceuticals, Inc. Income Statement

XFOR • NASDAQ

X4 Pharmaceuticals, Inc. Income StatementDec 2025Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020Dec 2019Dec 2018Dec 2017Dec 2016Dec 2015
REVENUE
35.1M
2.6M
0.0
0.0
0.0
3M
0.0
3.5M
0.0
0.0
0.0
GROSS PROFIT
(6.3M)
(797K)
(0.0)
(0.0)
(1.9M)
(0.0)
(672K)
(103K)
(195K)
(300K)
(400K)
28.9M
1.8M
0.0
0.0
-1.9M
3M
-672K
3.4M
-195K
-300K
-400K
OPERATING INCOME
(116.2M)
(38.2M)
(107.5M)
(87.6M)
(73.5M)
(62.9M)
(47.8M)
(46.2M)
(32.3M)
(22M)
(12.7M)
(43.5M)
(61.5M)
(35.5M)
(27M)
(24.7M)
(20.9M)
(17.6M)
(18.4M)
(8M)
(6.5M)
(2.1M)
(72.7M)
(81.6M)
(72M)
(61.1M)
(48.8M)
(41.9M)
(30.2M)
(31M)
(28.1M)
(17.8M)
(12.7M)
-86.9M
-36.4M
-107.5M
-87.6M
-75.3M
-59.9M
-51.7M
-45.9M
-36.1M
-24.3M
-14.8M
PRE-TAX INCOME
(8.9M)
(8.8M)
(5.8M)
(4M)
(3.6M)
(2.7M)
(2.1M)
(1M)
(2.1M)
(2.5M)
(472K)
-4.3M
-3M
-1.2M
-3.8M
-3.6M
-2.4M
-950K
-230K
-1.9M
0.0
0.0
(0.0)
-105M
(0.0)
-509K
(0.0)
(0.0)
(0.0)
-85K
-16K
(104K)
-77K
7.7M
-739K
6.4M
-6.3M
-13.3M
-2.1M
-1.1M
2.9M
2.3M
6.5M
1.6M
-79.2M
-37.1M
-101.1M
-93.8M
-88.7M
-62M
-52.8M
-43M
-33.9M
-23M
-13.2M
NET INCOME
(41K)
(310K)
(78K)
(28K)
(17K)
(148K)
(0.0)
(3.9M)
(0.0)
(2.6M)
(0.0)
-79.2M
-37.5M
-101.2M
-93.9M
-88.7M
-62.1M
-56.6M
-43M
-33.9M
-23M
-13.2M

SEC Filings

XFOR - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
8-K/A

8-K/A 2026 (Amended)

N/A

May 13, 2026
May 11, 2026
2026
8-K

8-K 2026

N/A

May 12, 2026
May 11, 2026
2026
10-Q

10-Q 2026 Q1

Q1

May 06, 2026
March 31, 2026
2026
S-3

S-3

N/A

May 06, 2026
May 06, 2026
 
DEF 14A

DEF 14A 2026

N/A

March 20, 2026
March 20, 2026
2026
10-K

10-K 2025 FY

FY

March 17, 2026
December 31, 2025
2025
10-Q

10-Q 2025 Q3

Q3

November 05, 2025
September 30, 2025
2025
8-K

8-K 2025

N/A

November 05, 2025
November 05, 2025
2025
8-K

8-K 2025

N/A

October 27, 2025
October 23, 2025
2025
8-K

8-K 2025

N/A

September 17, 2025
September 15, 2025
2025
Showing 1 to 10 of 206 filings