X4 Pharmaceuticals, Inc.

X4 Pharmaceuticals, Inc.

XFOR·NASDAQ

$4.08

+0.99%
HealthcareBiotechnology

X4 Pharmaceuticals, Inc., a late-stage clinical biopharmaceutical company, focuses on the research, development, and commercialization of novel therapeutics for the treatment of rare diseases. Its lead product candidate is mavorixafor, a small molecule inhibitor of the chemokine receptor C-X-C chemokine receptor type 4 (CXCR4), which is in Phase III clinical trial for the treatment of patients with warts, hypogammaglobulinemia, infections, and myelokathexis syndrome; and Phase Ib clinical trial to treat chronic neutropenia and Waldenström macroglobulinemia. The company is also developing X4P-002, a CXCR4 antagonist for the treatment of brain cancers; and X4P-003, a CXCR4 antagonist for the treatment of CXCR4 disorders and primary immunodeficiencies. It has a license agreement with Abbisko Therapeutics Co., Ltd. to develop, manufacture, and commercialize mavorixafor in combination with checkpoint inhibitors or other agents in oncology indications. The company was founded in 2010 and is headquartered in Boston, Massachusetts.

At a Glance

Live Snapshot
Market Cap$384.82M
EPS-1.8700
P/E Ratio-2.18
Earnings Date08/06/2026
xfor

X4 Pharmaceuticals, Inc. Street Expectations Map

XFOR · NASDAQ

Wall Street analysts project that XFOR stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 11.33, with estimates ranging from a low of 10.00 to a high of 12.00.

Lowest Target
10.00
145.10%
Consensus Target
11.33
177.70%
Highest Target
12.00
194.12%

The consensus 1-year price target stands at 11.33, with estimates ranging from a low of 10.00 to a high of 12.00.

Analyst Consensus Analysis

Upside Potential

+177.7%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

17.7% spread

High analyst agreement. Narrow target range indicates strong consensus on valuation, suggesting clear investment thesis and predictable outlook.

Analyst Conviction

Very High

Strong buy conviction: High upside with tight consensus suggests compelling investment opportunity backed by analyst confidence.

Market Sentiment Insight

Rare opportunity: Exceptional upside potential with strong analyst consensus creates a compelling setup. The combination of significant price target premium and tight agreement suggests high-conviction undervaluation that may attract institutional capital.

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X4 Pharmaceuticals, Inc. Forward Estimates of Revenue

XFOR · NASDAQ
Latest Revenue
35.11M
FY 2025
Avg Estimate
9.50M
FY 2026
Estimate Range
7.91M - 11.09M
Analyst Spread

Forward Growth Analysis

Projected Growth-72.9%

Significant contraction projected—major business challenges or industry disruption likely.

Analyst Coverage2 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread34%

Moderate uncertainty in forecasts—typical for companies with evolving business models.

OutlookCautious

Analyst skepticism evident—carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertainty—exercise caution.

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X4 Pharmaceuticals, Inc. Forward Estimates of Net Income

XFOR · NASDAQ
Latest Net Income
-79.20M
FY 2025
Avg Estimate
-30.67M
FY 2026
Estimate Range
-34.48M - -26.86M
Analyst Spread

Forward Growth Analysis

Projected Growth+61.3%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage2 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread25%

Moderate uncertainty in forecasts—typical for companies with evolving business models.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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X4 Pharmaceuticals, Inc. Forward Estimates of EPS

XFOR · NASDAQ
Latest EPS
-1.87
FY 2025
Avg Estimate
$-0.73
FY 2026
Estimate Range
$-0.82 - $-0.64
Analyst Spread

Forward Growth Analysis

Projected Growth+61.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage2 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread25%

Moderate uncertainty in forecasts—typical for companies with evolving business models.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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X4 Pharmaceuticals, Inc. Forward Estimates of EBIT

XFOR · NASDAQ
Latest EBIT
-86.88M
FY 2025
Avg Estimate
1.90M
FY 2026
Estimate Range
1.58M - 2.22M
Analyst Spread

Forward Growth Analysis

Projected Growth+102.2%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage2 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread34%

Moderate uncertainty in forecasts—typical for companies with evolving business models.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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X4 Pharmaceuticals, Inc. Forward Estimates of EBITDA

XFOR · NASDAQ
Latest EBITDA
-85.61M
FY 2025
Avg Estimate
1.90M
FY 2026
Estimate Range
1.58M - 2.22M
Analyst Spread

Forward Growth Analysis

Projected Growth+102.2%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage2 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread34%

Moderate uncertainty in forecasts—typical for companies with evolving business models.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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X4 Pharmaceuticals, Inc. Forward Estimates of SG&A Expense

XFOR · NASDAQ
Latest SG&A Expense
43.52M
FY 2025
Avg Estimate
53.77M
FY 2026
Estimate Range
44.75M - 62.78M
Analyst Spread

Forward Growth Analysis

Projected Growth+23.6%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage2 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread34%

Moderate uncertainty in forecasts—typical for companies with evolving business models.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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X4 Pharmaceuticals, Inc. Insider Positioning

XFOR · NASDAQ

During the last 12 months, insiders have purchased $250K and sold $73K worth of XFOR shares, resulting in $177K of net buying activity.

3 Months

Bought

0

0.00

Sold

17.0K

72.82K

Net Activity

-73K

-$73K

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

86.2K

250.00K

Sold

0

0.00

Net Activity

+250K

+$250K

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

1
CAR

Craig Adam R

Director, Officer: Executive Chairman

86.2K shares1 transactions

$250K

Top Sellers

1
KD

Kirske David

Officer: Chief Financial Officer

17.0K shares1 transactions

$73K

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $177K net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

3.43:1

Exceptional buy/sell ratio. Buying dramatically outweighs selling—one of the strongest possible insider signals.

Recent Trend (3 Months)

$73K

Heavy recent selling activity. Recent insider sales notably exceed purchases—may warrant investigation into company developments.

Insider Participation

Balanced

1 insider buyers and 1 sellers. Equal participation suggests mixed or neutral insider views.