Tenaya Therapeutics, Inc.

Tenaya Therapeutics, Inc.

TNYAยทNASDAQ

$0.79

+1.6%
HealthcareBiotechnology

Tenaya Therapeutics, Inc., a biotechnology company, discovers, develops, and delivers therapies for heart disease in the United States. It develops its products through cellular regeneration, gene therapy, and precision medicine platforms. The company is developing TN-201, an adeno-associated virus (AAV)-based gene therapy to address genetic hypertrophic cardiomyopathy (gHCM) caused by haploinsufficient myosin binding protein C3 (MYBPC3) gene mutations; and TN-301, a small molecule inhibitor of histone deacetylase 6 (HDAC6i) for use in heart failure with preserved ejection fraction (HFpEF) and genetic dilated cardiomyopathy (gDCM). It is also developing TN-401, an AAV-based gene therapy that addresses genetic arrhythmogenic right ventricular cardiomyopathy (gARVC) caused by plakophilin 2 (PKP2) gene mutations; an AAV-based gene therapy designed to deliver the dwarf open reading frame (DWORF) gene in the heart for DCM; and Reprogramming program, an AAV-based approach for cardiac regeneration to replace heart cells lost in patients experiencing heart failure due to prior myocardial infarction. The company was incorporated in 2016 and is headquartered in South San Francisco, California.

At a Glance

Live Snapshot
Market Cap$130.92M
EPS-0.5900
P/E Ratio-1.33
Earnings Date08/05/2026
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Tenaya Therapeutics, Inc. Street Expectations Map

TNYA ยท NASDAQ

Wall Street analysts project that TNYA stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 2.33, with estimates ranging from a low of 2.00 to a high of 3.00.

Lowest Target
2.00
154.52%
Consensus Target
2.33
196.51%
Highest Target
3.00
281.78%

The consensus 1-year price target stands at 2.33, with estimates ranging from a low of 2.00 to a high of 3.00.

Analyst Consensus Analysis

Upside Potential

+196.5%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

42.9% spread

Mixed analyst views. Wide target range suggests differing opinions on key value drivers, growth prospects, or risk factors.

Analyst Conviction

Moderate

Neutral sentiment. Fair value pricing with moderate agreement suggests wait-and-see approach or catalyst-driven opportunity.

Market Sentiment Insight

Monitor and evaluate: Current analyst consensus suggests limited conviction or near-term catalysts. Stay informed on company developments and reassess positioning as new information emerges.

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Tenaya Therapeutics, Inc. Forward Estimates of Revenue

TNYA ยท NASDAQ
Latest Revenue
0.00
FY 2025
Avg Estimate
4.00M
FY 2026
Estimate Range
4.00M - 4.00M
Analyst Spread

Forward Growth Analysis

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

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Tenaya Therapeutics, Inc. Forward Estimates of Net Income

TNYA ยท NASDAQ
Latest Net Income
-90.60M
FY 2025
Avg Estimate
-43.59M
FY 2026
Estimate Range
-48.99M - -38.20M
Analyst Spread

Forward Growth Analysis

Projected Growth+51.9%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread25%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Tenaya Therapeutics, Inc. Forward Estimates of EPS

TNYA ยท NASDAQ
Latest EPS
-0.59
FY 2025
Avg Estimate
$-0.51
FY 2026
Estimate Range
$-0.58 - $-0.45
Analyst Spread

Forward Growth Analysis

Projected Growth+13.7%

Solid growth trajectory indicates healthy business performance and competitive positioning.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread25%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

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Tenaya Therapeutics, Inc. Forward Estimates of EBIT

TNYA ยท NASDAQ
Latest EBIT
-93.33M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Tenaya Therapeutics, Inc. Forward Estimates of EBITDA

TNYA ยท NASDAQ
Latest EBITDA
-84.89M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Tenaya Therapeutics, Inc. Forward Estimates of SG&A Expense

TNYA ยท NASDAQ
Latest SG&A Expense
24.72M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth-100.0%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Tenaya Therapeutics, Inc. Insider Positioning

TNYA ยท NASDAQ

During the last 12 months, insiders have sold $659K worth of TNYA shares, with no buying activity reported.

3 Months

Bought

0

0.00

Sold

8.0K

6.34K

Net Activity

-6K

-$6K

3-6 Months

Bought

0

0.00

Sold

972.2K

631.75K

Net Activity

-632K

-$632K

6-9 Months

Bought

0

0.00

Sold

7.4K

9.80K

Net Activity

-10K

-$10K

9-12 Months

Bought

0

0.00

Sold

8.5K

10.62K

Net Activity

-11K

-$11K

Top Buyers

No buying activity

Top Sellers

1
CGIGL

Column Group Iii Gp, Lp

10 Percent Owner

971.6K sharesโ€ข4 transactions

$631K

2
AF

Ali Faraz

Director, Officer: Chief Executive Officer

11.4K sharesโ€ข3 transactions

$13K

3
TW

Tingley Whittemore

Officer: Chief Medical Officer

7.8K sharesโ€ข3 transactions

$9K

4
HT

Higa Tomohiro

Officer: Svp, Finance

5.2K sharesโ€ข4 transactions

$6K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $659K net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$6K

Heavy recent selling activity. Recent insider sales notably exceed purchasesโ€”may warrant investigation into company developments.

Insider Participation

High Selling

4 insider sellers vs. 0 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.