TriSalus Life Sciences, Inc.

TriSalus Life Sciences, Inc.

TLSIยทNASDAQ

$3.18

-0.47%
HealthcareMedical - Devices

TriSalus Life Sciences, Inc., an immunotherapy company that develops and commercializes immunotherapies for the treatment of liver and pancreatic tumors. The company offers the TriNav Infusion System for hepatic arterial infusion of liver tumors; and the Pancreatic Retrograde Venous Infusion System for pancreatic tumors. It also develops SD-101, an investigational immunotherapeutic with pressure-enabled drug delivery technology for hepatocellular carcinoma, intrahepatic cholangiocarcinoma, uveal melanoma with liver metastases, pancreatic ductal adenocarcinoma with liver metastases, colorectal cancer with liver metastases, and primary pancreatic cancers. The company is based in Westminster, Colorado.

At a Glance

Live Snapshot
Market Cap$120.55M
EPS-1.8400
P/E Ratio-1.73
Earnings Date08/11/2026

Intrinsic Alpha Methodology

Thesis Lenses

Signal ยท Driver ยท Risk

Signal

Medium confidence

Valuation multiple is compressed (P/E -1.7).

Valuation inputs: P/E -1.7, earnings yield N/A, momentum -0.5%.

If multiples stay elevated while momentum fades, downside repricing risk rises.

Driver

High confidence

Return profile is soft (ROE +1.2%, ROIC -1.1%).

Profitability stack: net margin -86.9%, ROE +1.2%, ROIC -1.1%.

Quality deterioration often appears in margins before it shows up in headline EPS.

Risk

High confidence

Downside profile is elevated and scenario stress-testing is essential.

Risk factors: liabilities/assets +195.8%, momentum -0.5%, net margin -86.9%.

Higher leverage with weak momentum and thin margins can amplify drawdown severity.

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TriSalus Life Sciences, Inc. Market vs Earnings Trajectory

TLSI ยท NASDAQ

Loading price and EPS data...

TriSalus Life Sciences, Inc.

TriSalus Life Sciences, Inc. Fair Value Envelope

TLSI ยท NASDAQ

Our analysis suggests that TLSI has a fair value of HIDDEN per share in the Base Case projection. With shares currently trading at $3.18, this represents a potential HIDDEN relative to our calculated worth for TriSalus Life Sciences, Inc..

Intrinsic Value
Current Price: $3.18
3Y+16.0%
5Y+7970.0%
10Y+7970.0%
3Y+264.0%
5Y-
10Y-
3Y-17.0%
5Y+23.0%
10Y+23.0%
3Y-44.0%
5Y+2558.0%
10Y+2558.0%
3Y-43.0%
5Y+2694.0%
10Y+2694.0%
3Y+61.0%
5Y+335.0%
10Y+335.0%
TriSalus Life Sciences, Inc.

TriSalus Life Sciences, Inc. Profit Bridge

TLSI ยท NASDAQ
Revenue45.15M
Cost of Goods Sold (6.96M)
Gross Profit38.19M
Operating Expenses (65.13M)
Operating Income-26.95M
Interest Expense (5.54M)
Other Income/Expense-12.27M
Pretax Income-39.22M
Income Tax (7.00K)
Net Income-39.23M
Net Income
-39.23M

Profitability Analysis

Gross Margin

84.6%

Exceptional pricing power and cost management. The company retains over half of revenue after direct costs.

Operating Margin

-59.7%

Operating losses indicate the core business is unprofitable. Requires restructuring or revenue growth.

Net Profit Margin

-86.9%

Net losses indicate the company is burning cash. Sustainability depends on path to profitability.

Profitability Insight

Margin squeeze alert: Healthy gross margins but weak operating margins suggest excessive operating expenses. Cost optimization could unlock significant value.

84.57%
Gross Profit Margin
-2%
3Y+3.0%
5Y-
10Y-
-59.68%
Operating Profit Margin
-51%
3Y-80.0%
5Y-
10Y-
-86.88%
Net Profit Margin
-23%
3Y-77.0%
5Y-
10Y-
115.85%
Return on Equity
-10%
3Y-70.0%
5Y+83.0%
10Y+83.0%
-111.03%
Return on Assets
-20%
3Y-48.0%
5Y-72.0%
10Y-72.0%
-112.28%
Return on Invested Capital
-57%
3Y-131.0%
5Y-4689.0%
10Y-4689.0%
TLSI

TriSalus Life Sciences, Inc. Cash Conversion Engine

TLSI ยท NASDAQ
Net Income-39.23M
Depreciation & Amortization626.00K
Stock-Based Compensation9.13M
Change in Working Capital2.07M
Others9.39M
Capital Expenditures-918.00K
Free Cash Flow-18.93M

Cash Flow Quality Analysis

FCF Conversion Rate

48.3%

Weak cash conversion. Significant portion of earnings not converting to cashโ€”review working capital trends and capital intensity.

CapEx Intensity

-5.1%

Asset-light business model. Low capital requirements leave more cash available for shareholders and growth investments.

FCF Growth Trend

+54.0%

Strong FCF growth demonstrates improving cash generation and business momentum. Positive signal for sustainability.

Working Capital Impact

+$2.07M

Working capital inflow boosted cash flow. Efficient management of receivables, inventory, and payables contributing positively.

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TriSalus Life Sciences, Inc. Funding & Solvency Profile

TLSI ยท NASDAQ
Cash & Cash Equivalents56.55M
Net Receivables5.21M
Inventory3.78M
Other Current Assets2.59M
Total Current Assets68 M
Property, Plant & Equipment2.77M
Goodwill & Intangible Assets0.00
Long-Term Investments0.00
Other Non-Current Assets69.00K
Total Non-Current Assets3 M
Total Assets
70.98M

Financial Health Analysis

Current Ratio

5.78x

Excellent liquidity position. The company can easily cover its short-term obligations with substantial cushion.

Debt-to-Equity Ratio

4.54x

High financial leverage. Heavy reliance on debt may indicate increased financial risk and potential solvency concerns.

Working Capital

56 M

Strong working capital position provides significant operational flexibility and financial cushion.

Asset Composition

96% Current

Asset-light business model with high liquidity. Majority of assets are easily convertible to cash.

Financial Health Insight

Mixed signals: Strong short-term liquidity provides comfort, but high overall leverage requires careful monitoring of debt servicing capabilities and refinancing risk.

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TriSalus Life Sciences, Inc. Street Expectations Map

TLSI ยท NASDAQ

Wall Street analysts project that TLSI stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 8.00, with estimates ranging from a low of 8.00 to a high of 8.00.

Lowest Target
8.00
151.57%
Consensus Target
8.00
151.57%
Highest Target
8.00
151.57%

The consensus 1-year price target stands at 8.00, with estimates ranging from a low of 8.00 to a high of 8.00.

Analyst Consensus Analysis

Upside Potential

+151.6%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

0.0% spread

High analyst agreement. Narrow target range indicates strong consensus on valuation, suggesting clear investment thesis and predictable outlook.

Analyst Conviction

Very High

Strong buy conviction: High upside with tight consensus suggests compelling investment opportunity backed by analyst confidence.

Market Sentiment Insight

Rare opportunity: Exceptional upside potential with strong analyst consensus creates a compelling setup. The combination of significant price target premium and tight agreement suggests high-conviction undervaluation that may attract institutional capital.

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TriSalus Life Sciences, Inc. Insider Positioning

TLSI ยท NASDAQ

During the last 12 months, insiders have purchased $4.33M and sold $136K worth of TLSI shares, resulting in $4.20M of net buying activity.

3 Months

Bought

470.0K

1.18M

Sold

34.2K

135.80K

Net Activity

+1.0M

+$1.04M

3-6 Months

Bought

318.3K

1.30M

Sold

0

0.00

Net Activity

+1.3M

+$1.30M

6-9 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

9-12 Months

Bought

353.9K

1.85M

Sold

0

0.00

Net Activity

+1.8M

+$1.85M

Top Buyers

1
SMP

Stansky Michael P

Director

653.9K sharesโ€ข2 transactions

$2.02M

2
PD

Patience David

Officer: Chief Financial Officer

252.6K sharesโ€ข2 transactions

$1.29M

3
WM

Wahlstrom Mats

Director

75.0K sharesโ€ข2 transactions

$234K

4
VW

Valle William

Director

45.5K sharesโ€ข2 transactions

$207K

5
SMT

Szela Mary T

Director, Officer: Ceo And President

30.5K sharesโ€ข1 transactions

$125K

Top Sellers

1
SMT

Szela Mary T

Director, Officer: Ceo And President

20.3K sharesโ€ข2 transactions

$79K

2
MR

Marshak Richard

Officer: Chief Commercial Officer

4.0K sharesโ€ข4 transactions

$16K

3
SJ

Stevens Jennifer

Officer: Chief Regulatory Officer

3.5K sharesโ€ข3 transactions

$15K

4
DJ

Devlin Jodi

Officer: Chief Of Clinical Operations

3.2K sharesโ€ข3 transactions

$13K

5
CBF

Cox Bryan F.

Officer: Chief Of Research

3.2K sharesโ€ข3 transactions

$13K

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $4.20M net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

31.89:1

Exceptional buy/sell ratio. Buying dramatically outweighs sellingโ€”one of the strongest possible insider signals.

Recent Trend (3 Months)

$1.04M

Very strong recent buying momentum. Recent insider purchases significantly outpace sales, suggesting near-term optimism.

Insider Participation

Balanced

5 insider buyers and 5 sellers. Equal participation suggests mixed or neutral insider views.

Insider Activity Insight

Strong confluence of bullish signals: High buy/sell ratio, multiple insiders participating, and recent buying momentum all point to significant insider confidence. This level of coordinated buying often precedes positive developments.

No Dividend Yield Data

TLSI has not reported any dividend yield values in the available annual periods.

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tlsi Dividend History

TLSI
10Y CAGR +0%
Latest $0
Annual $0
Stable dividend payments
Last Period: +0%