Senti Biosciences, Inc.

Senti Biosciences, Inc.

SNTI·NASDAQ

$2.39

-6.2%
HealthcareBiotechnology

Senti Biosciences, Inc. operates as a gene circuit company. The company develops cell and gene therapies engineered with gene circuits that are designed to reprogram cells with biological logic to sense inputs, compute decisions, and respond to respective cellular environments. Its synthetic biology platform utilizes off-the-shelf chimeric antigen receptor natural killer (CAR-NK) cells to target particularly challenging liquid and solid tumor oncology indications. The company's lead programs include SENTI-202, a Logic Gated OR+NOT off-the-shelf CAR-NK cell therapy designed to target and eliminate acute myeloid leukemia (AML) cells, while sparing the healthy bone marrow; and SENTI-301, a multi-armed off-the-shelf CAR-NK cell therapy designed for the treatment of hepatocellular carcinoma (HCC). It also develops SENTI-401, a Logic Gated (NOT) off-the-shelf CAR-NK cell therapy designed to target and eliminate colorectal cancer (CRC) cells, while sparing healthy cells in the body. The company was founded in 2016 and is based in South San Francisco, California.

At a Glance

Live Snapshot
Market Cap$62.83M
EPS-11.4900
P/E Ratio-0.31
Earnings Date03/18/2026
snti

Senti Biosciences, Inc. Street Expectations Map

SNTI · NASDAQ

Wall Street analysts project that SNTI stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 6.00, with estimates ranging from a low of 6.00 to a high of 6.00.

Lowest Target
6.00
151.05%
Consensus Target
6.00
151.05%
Highest Target
6.00
151.05%

The consensus 1-year price target stands at 6.00, with estimates ranging from a low of 6.00 to a high of 6.00.

Analyst Consensus Analysis

Upside Potential

+151.1%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

0.0% spread

High analyst agreement. Narrow target range indicates strong consensus on valuation, suggesting clear investment thesis and predictable outlook.

Analyst Conviction

Very High

Strong buy conviction: High upside with tight consensus suggests compelling investment opportunity backed by analyst confidence.

Market Sentiment Insight

Rare opportunity: Exceptional upside potential with strong analyst consensus creates a compelling setup. The combination of significant price target premium and tight agreement suggests high-conviction undervaluation that may attract institutional capital.

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Senti Biosciences, Inc. Forward Estimates of Revenue

SNTI · NASDAQ
Latest Revenue
0.00
FY 2024
Avg Estimate
1.00M
FY 2025
Estimate Range
1.00M - 1.00M
Analyst Spread

Forward Growth Analysis

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

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Senti Biosciences, Inc. Forward Estimates of Net Income

SNTI · NASDAQ
Latest Net Income
-52.79M
FY 2024
Avg Estimate
-12.09M
FY 2025
Estimate Range
-13.46M - -10.73M
Analyst Spread

Forward Growth Analysis

Projected Growth+77.1%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread23%

Moderate uncertainty in forecasts—typical for companies with evolving business models.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Senti Biosciences, Inc. Forward Estimates of EPS

SNTI · NASDAQ
Latest EPS
-11.49
FY 2024
Avg Estimate
$-2.72
FY 2025
Estimate Range
$-2.93 - $-2.33
Analyst Spread

Forward Growth Analysis

Projected Growth+76.3%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread22%

Moderate uncertainty in forecasts—typical for companies with evolving business models.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Senti Biosciences, Inc. Forward Estimates of EBIT

SNTI · NASDAQ
Latest EBIT
-60.73M
FY 2024
Avg Estimate
-600.00K
FY 2025
Estimate Range
-600.00K - -600.00K
Analyst Spread

Forward Growth Analysis

Projected Growth+99.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

snti

Senti Biosciences, Inc. Forward Estimates of EBITDA

SNTI · NASDAQ
Latest EBITDA
-54.88M
FY 2024
Avg Estimate
-600.00K
FY 2025
Estimate Range
-600.00K - -600.00K
Analyst Spread

Forward Growth Analysis

Projected Growth+98.9%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Senti Biosciences, Inc. Forward Estimates of SG&A Expense

SNTI · NASDAQ
Latest SG&A Expense
23.51M
FY 2024
Avg Estimate
12.59M
FY 2025
Estimate Range
12.59M - 12.59M
Analyst Spread

Forward Growth Analysis

Projected Growth-46.4%

Significant contraction projected—major business challenges or industry disruption likely.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Senti Biosciences, Inc. Insider Positioning

SNTI · NASDAQ

During the last 12 months, insiders have purchased $270K worth of SNTI shares, with no selling activity reported.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

9-12 Months

Bought

131.7K

269.98K

Sold

0

0.00

Net Activity

+270K

+$270K

Top Buyers

1
TDF

Tang Donald F

Director

21.9K shares1 transactions

$45K

2
CJJ

Collins James J.

Director

21.9K shares1 transactions

$45K

3
CB

Cooperstone Brenda

Director

21.9K shares1 transactions

$45K

4
HF

Hsiung Feng

Director

21.9K shares1 transactions

$45K

5
SF

Schulz Fran

Director

21.9K shares1 transactions

$45K

Top Sellers

No selling activity

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $270K net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

∞:1

Perfect buy/sell ratio. Only buying activity with zero selling—the most bullish possible insider signal.

Insider Participation

High Buying

5 insider buyers vs. 0 sellers. Broad-based buying across management team suggests widespread confidence.

Insider Activity Insight

Compelling insider conviction: The combination of strong buy/sell ratio and multiple buyers suggests insiders see attractive risk/reward. Consider this alongside fundamental analysis for confirmation.