Syndax Pharmaceuticals, Inc.

Syndax Pharmaceuticals, Inc.

SNDXยทNASDAQ

$18.34

-2.7%
HealthcareBiotechnology

Syndax Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, develops therapies for the treatment of cancer. Its lead product candidates are SNDX-5613, which is in phase 1/2 clinical trial targeting the binding interaction of Menin with the mixed lineage leukemia 1 protein for the treatment of MLL-rearranged (MLLr) and nucleophosmin 1 mutant acute myeloid leukemia (NPM1c AML); and SNDX-6352 or axatilimab, a monoclonal antibody that blocks the colony stimulating factor 1, or CSF-1 receptor for the treatment of patients with chronic graft versus host disease (cGVHD). The company is also developing Entinostat. It also has collaborative research and development agreement with National Cancer Institute; a clinical trial agreement with Eastern Cooperative Oncology Group; and a license agreement with Kyowa Hakko Kirin Co., Ltd. Syndax Pharmaceuticals, Inc. was incorporated in 2005 and is headquartered in Waltham, Massachusetts.Massachusetts.

At a Glance

Live Snapshot
Market Cap$1.63B
EPS-3.2900
P/E Ratio-5.57
Earnings Date08/03/2026
3Y+142.0%
5Y+353.0%
10Y+819.0%
3Y-256.0%
5Y-303.0%
10Y-1678.0%
3Y-92.0%
5Y-96.0%
10Y-75.0%
SNDX

Syndax Pharmaceuticals, Inc. Cash Conversion Engine

SNDX ยท NASDAQ
Net Income-285.42M
Depreciation & Amortization6.00K
Stock-Based Compensation47.50M
Change in Working Capital-79.32M
Others-5.75M
Capital Expenditures-187.00K
Free Cash Flow-323.17M

Cash Flow Quality Analysis

FCF Conversion Rate

113.2%

Excellent cash generation. The company converts earnings to cash at or above 100%, indicating high-quality earnings.

CapEx Intensity

-0.1%

Asset-light business model. Low capital requirements leave more cash available for shareholders and growth investments.

FCF Growth Trend

-17.6%

Significant FCF decline raises concerns. Urgent review needed of operational performance and capital allocation.

Working Capital Impact

-$79.32M

Moderate working capital outflow. Typical for growing businesses, but ensure it's supporting revenue growth, not inefficiency.

Cash Flow Quality Insight

Working capital strain: Significant cash tied up in operations. Monitor receivables collection, inventory turns, and payment terms to optimize cash conversion cycle.

Syndax Pharmaceuticals, Inc. Cash Flow Statement

SNDX โ€ข NASDAQ

Syndax Pharmaceuticals, Inc. Cash Flow StatementDec 2025Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020Dec 2019Dec 2018Dec 2017Dec 2016Dec 2015Dec 2014Dec 2013Dec 2012Dec 2011
OPERATING ACTIVITIES
-285.4M
-318.8M
-209.4M
-149.3M
24.9M
-73.2M
-56M
-74M
-60.8M
-44.5M
-24.1M
-19.8M
-14.2M
-10M
-13.1M
6K
8K
12K
33K
43K
89K
92K
78K
76K
89K
21K
15K
13K
34K
51K
0.0
0.0
0.0
0.0
255K
0.0
-780K
-558K
223K
1.6M
2.5M
2.6M
1.7M
-3.4M
0.0
47.5M
43M
31M
16M
13.3M
9.1M
6M
6.2M
5.5M
4.7M
3.9M
2.3M
1.4M
139K
0.0
-5.7M
-12.4M
-14.1M
-2M
187K
686K
359K
11K
8K
25K
762K
40K
3.7M
3.1M
2.9M
-79.3M
13.3M
31.9M
1.7M
-9.6M
-7.9M
-241K
-302K
7.7M
2.9M
14.6M
551K
31K
823K
141K
-323M
-274.9M
-160.6M
-133.7M
29.1M
-71.3M
-50.6M
-68.5M
-47.4M
-35.2M
-2.4M
-14.4M
-7.3M
-9.3M
-10M
INVESTING ACTIVITIES
-187K
(0.0)
(0.0)
-225K
-129K
(0.0)
(0.0)
-187K
-84K
-261K
-49K
-4K
-38K
-11K
-8K
(0.0)
(0.0)
(0.0)
(225K)
(40.7K)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
-195.8M
-557.1M
-354.6M
-495.3M
-294.7M
-278.9M
-104M
-78.8M
-152.3M
-158.3M
-102M
-3.4M
-4M
(0.0)
-500K
486M
337.3M
472.2M
308.9M
254M
136.4M
116.8M
130.4M
135.3M
140.3M
40.5M
5.3M
0.0
500K
2.7M
0.0
0.0
0.0
225K
-40.7K
0.0
12.8K
51.6K
45K
-97K
-118K
-1K
33K
5K
-50K
(290M)
-219.8M
(117.6M)
-186.2M
-40.9M
-142.5M
(12.8M)
(51.4M)
-17M
-18.4M
-61.7M
(1.9M)
-4M
(494K)
(2.2M)
FINANCING ACTIVITIES
13.7M
9.7M
258.1M
181.4M
86.3M
278.1M
28.2M
15.5M
75.3M
52.1M
0.0
0.0
0.0
0.0
3K
0.0
0.0
0.0
-21M
0.0
19.7M
0.0
0.0
0.0
0.0
-9M
14M
-3.7M
6.3M
8.6M
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
-2.6M
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
0.0
343.7M
6M
11.9M
32.1M
6.6M
360K
232K
374K
4.7M
-1.1M
-1.6M
24.6M
-597K
0.0
13.7M
353.4M
264.1M
172.3M
118.5M
304.4M
28.6M
15.7M
75.7M
54.2M
77.3M
12.4M
20.9M
5.7M
8.6M
CASH FLOW SUMMARY
-19.3M
-141.3M
221.1M
-147.6M
106.7M
90.6M
-9.3M
-1.4M
11.3M
665K
13.2M
-95K
9.6M
-3.1M
0.0
154.3M
295.6M
74.5M
222.1M
115.4M
24.7M
34M
35.4M
23.8M
23.2M
10M
10.1M
537K
3.6M
0.0
135M
154.3M
295.6M
74.5M
222.1M
115.4M
24.7M
34M
35.2M
23.8M
23.2M
10M
10.1M
537K
3.7M
-323.2M
-274.9M
-160.6M
-133.9M
29M
-71.3M
-50.6M
-68.7M
-47.5M
-35.4M
-2.5M
-14.4M
-7.3M
-9.3M
-10M

SEC Filings

SNDX - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
8-K

8-K 2026

N/A

April 30, 2026
April 30, 2026
2026
DEF 14A

DEF 14A 2026

N/A

April 30, 2026
April 30, 2026
2026
10-Q

10-Q 2026 Q1

Q1

April 30, 2026
March 31, 2026
2026
10-K

10-K 2025 FY

FY

February 26, 2026
December 31, 2025
2025
8-K

8-K 2026

N/A

February 26, 2026
February 26, 2026
2026
8-K

8-K 2026

N/A

January 12, 2026
January 12, 2026
2026
8-K

8-K 2025

N/A

December 19, 2025
December 18, 2025
2025
8-K

8-K 2025

N/A

November 03, 2025
November 03, 2025
2025
10-Q

10-Q 2025 Q3

Q3

November 03, 2025
September 30, 2025
2025
8-K

8-K 2025

N/A

October 24, 2025
October 24, 2025
2025
Showing 1 to 10 of 177 filings