Simulations Plus, Inc.

Simulations Plus, Inc.

SLPยทNASDAQ

$16.17

-3.6%
HealthcareMedical - Healthcare Information Services

Simulations Plus, Inc. develops drug discovery and development software for modeling and simulation, and prediction of molecular properties utilizing artificial intelligence and machine learning based technology worldwide. It operates through four segments: Simulations Plus, Cognigen, DILIsym, and Lixoft. The company offers GastroPlus, which simulates the absorption and drug interaction of compounds administered to humans and animals; and DDDPlus and MembranePlus simulation products. It also provides products based on mechanistic and mathematical models, such as DILIsym, a quantitative systems pharmacology software; NAFLDsym; IPFsym; RENAsym; and MITOsym. In addition, the company provides Absorption, Distribution, Metabolism, Excretion, and Toxicity Predictor for chemistry-based computer program that takes molecular structures as inputs and predicts their properties; and MedChem Designer, as well as modeling and simulation products comprising MonolixSuite and PKPlus. Further, it provides population modeling and simulation contract research services; training and consulting services designed to accelerate pharmacometrics studies; and clinical-pharmacology-based consulting services in support of regulatory submissions. The company serves pharmaceutical, biotechnology, agrochemical, cosmetics, and food companies, as well as academic and regulatory agencies. Simulations Plus, Inc. was incorporated in 1996 and is headquartered in Lancaster, California.

At a Glance

Live Snapshot
Market Cap$326.72M
EPS-3.2200
P/E Ratio-5.02
Earnings Date07/13/2026
-52.61%
Return on Invested Capital
-2197%
3Y-883.0%
5Y-1004.0%
10Y-376.0%
-51.86%
Return on Equity
-1050%
3Y-840.0%
5Y-967.0%
10Y-338.0%
-49.05%
Return on Assets
-1123%
3Y-849.0%
5Y-985.0%
10Y-378.0%
Simulations Plus, Inc.

Simulations Plus, Inc. Management Team

SLP ยท NASDAQ
MJ

Ms. Jennifer Presnell

Accounting Manager

female
MD

Mr. Daniel Szot

Chief Revenue Officer

Compensation

$432,282

male
MV

Ms. Viera Lukacova Ph.D.

Chief Science Officer

female
MT

Ms. Tanya Marvin

Marketing Manager

female
MJ

Ms. Jill Fiedler-Kelly M.S.

President of Clinical Pharmacology & Pharmacometrics Solutions

Compensation

$393,770

Born 1970(Age 56)
female
MJ

Mr. John Anthony DiBella M.S.

President of PBPK & Cheminformatics Solutions

Compensation

$364,624

Born 1980(Age 46)
male
MS

Mr. Steven Chang

President of Quantitative Systems Pharmacology

Compensation

$359,414

Born 1969(Age 57)
male
MJ

Mr. Josh Fohey

Senior Vice President of Operations

male
DB

Dr. Bud Nelson J.D., Ph.D.

Vice President of Corporate Counsel & Personal Data Protection Officer

ML

Ms. Lindsay Luke

Vice President of Human Resources

female
slp

Simulations Plus, Inc. Insider Positioning

SLP ยท NASDAQ

During the last 12 months, insiders have purchased $2.20M and sold $1.11M worth of SLP shares, resulting in $1.10M of net buying activity.

3 Months

Bought

0

0.00

Sold

33.0K

533.28K

Net Activity

-533K

-$533K

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

137.5K

2.20M

Sold

20.9K

322.44K

Net Activity

+1.9M

+$1.88M

9-12 Months

Bought

0

0.00

Sold

14.0K

250.56K

Net Activity

-251K

-$251K

Top Buyers

1
OS

Oconnor Shawn

Officer: Chief Executive Officer

50.0K sharesโ€ข1 transactions

$801K

2
FWW

Frederick William W

Officer: Evp/Cfo

32.5K sharesโ€ข1 transactions

$521K

3
DJAI

Dibella John Anthony Ii

Officer: Chief Revenue Officer

27.5K sharesโ€ข1 transactions

$441K

4
FJ

Fiedler-Kelly Jill

Officer: President, Services Solutions

27.5K sharesโ€ข1 transactions

$441K

Top Sellers

1
WWS

Woltosz Walter S

Director, 10 Percent Owner:

62.2K sharesโ€ข4 transactions

$1.02M

2
LL

Lavange Lisa

Director

2.6K sharesโ€ข3 transactions

$38K

3
DJAI

Dibella John Anthony Ii

Officer: Chief Revenue Officer

2.0K sharesโ€ข2 transactions

$28K

4
FJ

Fiedler-Kelly Jill

Officer: President, Services Solutions

1.0K sharesโ€ข1 transactions

$17K

Insider Activity Analysis

Net Insider Sentiment

Bullish

Moderately bullish with $1.10M net buying. Insiders show cautious optimism through measured share purchases.

Buy/Sell Ratio

1.99:1

Positive buy/sell ratio. Buying exceeds or matches selling, indicating net positive insider sentiment.

Recent Trend (3 Months)

$533K

Heavy recent selling activity. Recent insider sales notably exceed purchasesโ€”may warrant investigation into company developments.

Insider Participation

Balanced

4 insider buyers and 4 sellers. Equal participation suggests mixed or neutral insider views.

Insider Activity Insight

Broad-based insider buying: When multiple insiders independently decide to purchase shares, it often reflects genuine confidence rather than coordinated optics. This pattern deserves attention, especially if buying followed a price decline.

SEC Filings

SLP - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2025

N/A

December 29, 2025
December 29, 2025
2025
DEF 14A

DEF 14A 2024

N/A

December 23, 2024
December 23, 2024
2024
DEF 14A

DEF 14A 2023

N/A

December 22, 2023
December 22, 2023
2023
DEF 14A

DEF 14A 2022

N/A

December 23, 2022
December 23, 2022
2022
DEF 14A

DEF 14A 2021

N/A

December 17, 2021
February 11, 2021
2021
DEF 14A

DEF 14A 2021

N/A

May 11, 2021
June 23, 2021
2021
DEF 14A

DEF 14A 2021

N/A

December 29, 2020
February 25, 2021
2021
DEF 14A

DEF 14A 2020

N/A

December 30, 2019
February 21, 2020
2020
DEF 14A

DEF 14A 2019

N/A

December 31, 2018
February 22, 2019
2019
DEF 14A

DEF 14A 2018

N/A

December 29, 2017
February 26, 2018
2018
Showing 1 to 10 of 27 filings