SB

Sagimet Biosciences Inc.

SGMT·NASDAQ

$6.86

+1.3%
HealthcareBiotechnology

Sagimet Biosciences Inc., a clinical-stage biopharmaceutical company, develops therapeutics called fatty acid synthase (FASN) inhibitors for the treatment of diseases that result from dysfunctional lipid metabolism pathways. Its lead drug candidate is Denifanstat, a FASN inhibitor for the treatment of nonalcoholic steatohepatitis and acne. The company is also developing TVB-3567, a FASN inhibitor for the treatment of various types of cancers. The company was formerly known as 3-V Biosciences, Inc. and changed its name to Sagimet Biosciences Inc. in August 2019. Sagimet Biosciences Inc. was incorporated in 2006 and is headquartered in San Mateo, California.

At a Glance

Live Snapshot
Market Cap$223.51M
EPS-1.5800
P/E Ratio-4.34
Earnings Date08/12/2026
-51.04%
Return on Invested Capital
46%
3Y-54.0%
5Y+201.0%
10Y-67.0%
-45.82%
Return on Equity
57%
3Y-381.0%
5Y-648.0%
10Y-503.0%
-43.82%
Return on Assets
54%
3Y-53.0%
5Y+166.0%
10Y-66.0%
SB

Sagimet Biosciences Inc. Management Team

SGMT · NASDAQ
MD

Mr. David A. Happel

Chief Executive Officer, President & Director

Compensation

$906,164

Born 1962(Age 64)
male
MT

Mr. Thierry Chauche

Chief Financial Officer & Principal Accounting Officer

Compensation

$598,045

Born 1976(Age 50)
male
DE

Dr. Eduardo Bruno Martins DPhil, M.D., Ph.D.

Chief Medical Officer

Compensation

$669,064

Born 1963(Age 63)
DL

Dr. Lucas Pelkmans Ph.D.

Co-Founder

MU

Mr. Urs Greber Ph.D.

Co-Founder

male
ME

Ms. Elizabeth Rozek Esq., J.D.

General Counsel & Chief Compliance Officer

Born 1972(Age 54)
female
MR

Mr. Robert D'Urso

Senior Vice President of New Products

male
DM

Dr. Marie O'Farrell Ph.D.

Senior Vice President of Research & Development

s

Sagimet Biosciences Inc. Insider Positioning

SGMT · NASDAQ

During the last 12 months, insiders have purchased $1.31M and sold $1.17M worth of SGMT shares, resulting in $141K of net buying activity.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

0

0.00

Sold

19.7K

105.46K

Net Activity

-105K

-$105K

6-9 Months

Bought

0

0.00

Sold

37.7K

289.98K

Net Activity

-290K

-$290K

9-12 Months

Bought

244.3K

1.31M

Sold

84.5K

772.19K

Net Activity

+537K

+$537K

Top Buyers

1
SBC

Seidenberg Beth C

Director

60.8K shares2 transactions

$330K

2
HPW

Hoelscher Paul W.

Director

32.3K shares1 transactions

$172K

3
GEA

Grammer Elizabeth A

Director

32.3K shares1 transactions

$172K

4
KG

Kemble George

Director

32.3K shares1 transactions

$172K

5
WTP

Walbert Timothy P

Director

32.3K shares1 transactions

$172K

Top Sellers

1
HD

Happel David

Director, Officer: President & Ceo

77.6K shares2 transactions

$663K

2
KG

Kemble George

Director, Officer: Executive Chairman

37.7K shares1 transactions

$290K

3
RE

Rozek Elizabeth

Officer: Chief Legal & Admin. Officer

13.4K shares2 transactions

$113K

4
MEB

Martins Eduardo Bruno

Officer: Chief Medical Officer

11.9K shares2 transactions

$95K

5
CT

Chauche Thierry

Officer: Chief Financial Officer

1.3K shares1 transactions

$7K

Insider Activity Analysis

Net Insider Sentiment

Bullish

Moderately bullish with $141K net buying. Insiders show cautious optimism through measured share purchases.

Buy/Sell Ratio

1.12:1

Positive buy/sell ratio. Buying exceeds or matches selling, indicating net positive insider sentiment.

Insider Participation

Balanced

5 insider buyers and 5 sellers. Equal participation suggests mixed or neutral insider views.

Insider Activity Insight

Broad-based insider buying: When multiple insiders independently decide to purchase shares, it often reflects genuine confidence rather than coordinated optics. This pattern deserves attention, especially if buying followed a price decline.

SEC Filings

SGMT - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

April 21, 2026
June 12, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 30, 2025
June 09, 2025
2025
DEF 14A

DEF 14A 2024

N/A

April 18, 2024
June 05, 2024
2024
Showing 1 to 3 of 3 filings