Sangamo Therapeutics, Inc.

Sangamo Therapeutics, Inc.

SGMOยทNASDAQ

$0.22

+1.8%
HealthcareBiotechnology

Sangamo Therapeutics, Inc., a clinical-stage biotechnology company, focuses on translating science into genomic medicines that transform patients' lives using platform technologies in gene therapy, cell therapy, genome editing, and genome regulation. The company offers zinc finger protein (ZFP), a technology platform for making zinc finger nucleases, which are proteins used in modifying DNA sequences by adding or knocking out specific genes; and ZFP transcription factors proteins used in increasing or decreasing gene expression. It develops SB-525, which is in Phase III AFFINE clinical trial for the treatment of hemophilia A; ST-920, a gene therapy, which is in Phase I/II STAAR clinical trials for the treatment of Fabry disease; and SAR445136, a cell therapy, which is in Phase I/II PRECIZN-1 clinical trials for the treatment of sickle cell disease. The company also develops TX200, chimeric antigen receptor for the treatment of HLA-A2 mismatched kidney transplant rejection; KITE-037, a cell therapy for the treatment of cancer; ST-501 for the treatment of tauopathies; and ST-502 for the treatment of synucleinopathies, including Parkinson's disease and neuromuscular disease. It has collaborative and strategic partnerships with Biogen MA, Inc.; Kite Pharma, Inc.; Pfizer Inc.; Sanofi S.A.; Novartis Institutes for BioMedical Research, Inc.; Shire International GmbH; Dow AgroSciences LLC; Sigma-Aldrich Corporation; Genentech, Inc.; Open Monoclonal Technology, Inc.; F. Hoffmann-La Roche Ltd and Hoffmann-La Roche Inc.; and California Institute for Regenerative Medicine. The company was formerly known as Sangamo BioSciences, Inc. and changed its name to Sangamo Therapeutics, Inc. in January 2017. Sangamo Therapeutics, Inc. was incorporated in 1995 and is headquartered in Brisbane, California.

At a Glance

Live Snapshot
Market Cap$91.14M
EPS-0.4400
P/E Ratio-0.50
Earnings Date08/06/2026
sgmo

Sangamo Therapeutics, Inc. Street Expectations Map

SGMO ยท NASDAQ

Wall Street analysts project that SGMO stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 7.25, with estimates ranging from a low of 2.00 to a high of 19.00.

Lowest Target
2.00
809.09%
Consensus Target
7.25
3195.45%
Highest Target
19.00
8536.36%

The consensus 1-year price target stands at 7.25, with estimates ranging from a low of 2.00 to a high of 19.00.

Analyst Consensus Analysis

Upside Potential

+3195.4%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

234.5% spread

High uncertainty. Very wide target spread indicates significant disagreement among analystsโ€”major valuation uncertainty or transformation underway.

Analyst Conviction

Low

High uncertainty: Wide dispersion indicates analysts struggle to agree on valuationโ€”proceed with caution and independent analysis.

Market Sentiment Insight

High risk, high reward: Substantial upside potential exists, but wide analyst disagreement signals execution risk or unclear catalysts. Thorough due diligence essential before committing capital.

sgmo

Sangamo Therapeutics, Inc. Forward Estimates of Revenue

SGMO ยท NASDAQ
Latest Revenue
39.55M
FY 2025
Avg Estimate
55.38M
FY 2026
Estimate Range
35.04M - 86.68M
Analyst Spread

Forward Growth Analysis

Projected Growth+40.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread93%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

sgmo

Sangamo Therapeutics, Inc. Forward Estimates of Net Income

SGMO ยท NASDAQ
Latest Net Income
-122.93M
FY 2025
Avg Estimate
-78.28M
FY 2026
Estimate Range
-110.30M - -33.22M
Analyst Spread

Forward Growth Analysis

Projected Growth+36.3%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread98%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

sgmo

Sangamo Therapeutics, Inc. Forward Estimates of EPS

SGMO ยท NASDAQ
Latest EPS
-0.44
FY 2025
Avg Estimate
$-0.32
FY 2026
Estimate Range
$-0.55 - $-0.16
Analyst Spread

Forward Growth Analysis

Projected Growth+28.4%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage2 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread121%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

sgmo

Sangamo Therapeutics, Inc. Forward Estimates of EBIT

SGMO ยท NASDAQ
Latest EBIT
-108.00M
FY 2025
Avg Estimate
-51.78M
FY 2026
Estimate Range
-81.05M - -32.76M
Analyst Spread

Forward Growth Analysis

Projected Growth+52.1%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread93%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

sgmo

Sangamo Therapeutics, Inc. Forward Estimates of EBITDA

SGMO ยท NASDAQ
Latest EBITDA
-100.40M
FY 2025
Avg Estimate
-50.38M
FY 2026
Estimate Range
-78.87M - -31.88M
Analyst Spread

Forward Growth Analysis

Projected Growth+49.8%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread93%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

sgmo

Sangamo Therapeutics, Inc. Forward Estimates of SG&A Expense

SGMO ยท NASDAQ
Latest SG&A Expense
34.89M
FY 2025
Avg Estimate
31.26M
FY 2026
Estimate Range
19.78M - 48.94M
Analyst Spread

Forward Growth Analysis

Projected Growth-10.4%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread93%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

sgmo

Sangamo Therapeutics, Inc. Insider Positioning

SGMO ยท NASDAQ

During the last 12 months, insiders have purchased $201K and sold $500K worth of SGMO shares, resulting in $299K of net selling activity.

3 Months

Bought

0

0.00

Sold

415.8K

106.88K

Net Activity

-107K

-$107K

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

0

0.00

Sold

372.9K

275.56K

Net Activity

-276K

-$276K

9-12 Months

Bought

400.0K

201.20K

Sold

242.5K

117.75K

Net Activity

+83K

+$83K

Top Buyers

1
HMA

Horn Margaret A

Director

50.0K sharesโ€ข1 transactions

$25K

2
BC

Beers Courtney

Director

50.0K sharesโ€ข1 transactions

$25K

3
MJR

Meyers James R

Director

50.0K sharesโ€ข1 transactions

$25K

4
SKL

Smith Karen L.

Director

50.0K sharesโ€ข1 transactions

$25K

5
PHS

Parker H Stewart

Director

50.0K sharesโ€ข1 transactions

$25K

Top Sellers

1
MS

Macrae Sandy

Director, Officer: President, Ceo And Director

261.4K sharesโ€ข3 transactions

$149K

2
DN

Dubois-Stringfellow Nathalie

Officer: Svp-Chief Development Officer

423.3K sharesโ€ข4 transactions

$134K

3
JN

Jain Nikunj

Officer: Principal Accounting Officer

106.2K sharesโ€ข2 transactions

$100K

4
DP

Duraibabu Prathyusha

Officer: Principal Financial Officer

78.9K sharesโ€ข3 transactions

$46K

5
WSB

Willoughby Scott B.

Officer: Svp, Chief Legal Officer, Secy

77.4K sharesโ€ข3 transactions

$45K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Negative insider sentiment with $299K net selling. Selling notably exceeds buying, warranting closer scrutiny of company fundamentals.

Buy/Sell Ratio

0.40:1

Weak buy/sell ratio. Selling significantly exceeds buyingโ€”monitor for potential fundamental concerns.

Recent Trend (3 Months)

$107K

Heavy recent selling activity. Recent insider sales notably exceed purchasesโ€”may warrant investigation into company developments.

Insider Participation

Balanced

5 insider buyers and 5 sellers. Equal participation suggests mixed or neutral insider views.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.