SI

Septerna, Inc.

SEPNยทNASDAQ

$30.55

+2.0%
HealthcareBiotechnology

Septerna, Inc., a clinical-stage biotechnology company, discovers and develops G protein-coupled receptor (GPCR) oral small molecule products candidates for the treatment of endocrinology, immunology and inflammation, and metabolic diseases. The company develops SEP-786, an oral small molecule PTH1R agonist for hypoparathyroidism; SEP-631, an oral small molecule MRGPRX2 NAM for chronic spontaneous urticaria and other mast cell diseases; TSHR Program, an oral small molecule TSHR NAM for Graves' disease and thyroid eye disease. It also develops oral small molecule single- and multi-incretin receptor agonists for metabolic disorders including obesity and type 2 diabetes. Septerna, Inc. was formerly known as GPCR NewCo, Inc. and changed its name to Septerna Inc. in June 2021. The company was incorporated in 2019 and is headquartered in South San Francisco, California.

At a Glance

Live Snapshot
Market Cap$1.38B
EPS-1.1000
P/E Ratio-27.77
Earnings Date08/10/2026
SI

Septerna, Inc. Fair Value Envelope

SEPN ยท NASDAQ

Our analysis suggests that SEPN has a fair value of HIDDEN per share in the Base Case projection. With shares currently trading at $30.55, this represents a potential HIDDEN relative to our calculated worth for Septerna, Inc..

Intrinsic Value
Current Price: $30.55

Owner Earnings Valuation Tool

Warren Buffett's Owner Earnings DCF analysis for intrinsic value calculation

Historical Financial Data

Base year metrics used for projections

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Projection Settings

Forecast period and terminal assumptions

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DCF Valuation Summary

Calculation flow from present value to intrinsic value per share

Present Value$1,000.9B
+ Cash & Equivalents$120.7M
Firm Value$1,001.0B
- Debt$23.6M
Equity Value$1,001.0B
/ Shares Outstanding44,585,135B
DCF Value$22.5K
UNDERVALUED BY 73392%

Owner Earnings Projections

Operating Cash Flow - Maintenance CapEx = Owner Earnings

Metric
Year 1
Year 2
Year 3
Year 4
Year 5
Year 6
Year 7
Year 8
Year 9
Year 10
Operating Cash Flow
$220.4M
$440.8M
$881.5M
$1.8B
$3.5B
$7.1B
$14.1B
$28.2B
$56.4B
$112.8B
Maintenance CapEx
-$207.2K
-$414.4K
-$828.8K
-$1.7M
-$3.3M
-$6.6M
-$13.3M
-$26.5M
-$53.0M
-$106.1M
Owner Earnings
$220.2M
$440.3M
$880.7M
$1.8B
$3.5B
$7.0B
$14.1B
$28.2B
$56.4B
$112.7B
Discount Factor
0.926
0.857
0.794
0.735
0.681
0.630
0.583
0.540
0.500
0.463
Present Value
$203.9M
$377.5M
$699.1M
$1.3B
$2.4B
$4.4B
$8.2B
$15.2B
$28.2B
$52.2B
Terminal Value represents 88.7% of Enterprise Value