Revolution Medicines, Inc.

Revolution Medicines, Inc.

RVMDยทNASDAQ

$155.99

+3.1%
HealthcareBiotechnology

Revolution Medicines, Inc., a clinical-stage precision oncology company, focuses on developing therapies to inhibit frontier targets in RAS-addicted cancers. The company is developing RMC-4630, an inhibitor of SHP2, which is in Phase 1/2 clinical trial for the treatment of solid tumors, such as gynecologic and colorectal cancer tumors. It also develops RMC-5845, a selective inhibitor of SOS1, a protein that converts RAS (OFF) to RAS (ON) in cells; and RMC-5552, a hyperactivated selective inhibitor of mTORC1 signaling in tumors. In addition, the company is developing RMC-6291, a mutant-selective inhibitor of KRASG12C(ON) and NRASG12C(ON); and RMC-6236, a RAS-selective inhibitor of multiple RAS(ON) variants. Further, it develops RAS(ON) Inhibitors targeting KRASG13C(ON) and KRASG12D(ON). The company has a collaboration agreement with Sanofi for the research and development of SHP2 inhibitors, including RMC-4630. Revolution Medicines, Inc. was incorporated in 2014 and is headquartered in Redwood City, California.

At a Glance

Live Snapshot
Market Cap$33.16B
EPS-5.9500
P/E Ratio-26.22
Earnings Date08/05/2026
rvmd

Revolution Medicines, Inc. Street Expectations Map

RVMD ยท NASDAQ

Wall Street analysts project that RVMD stock may experience modest gains over the coming 12 months. The consensus 1-year price target stands at 165.33, with estimates ranging from a low of 73.00 to a high of 205.00.

Lowest Target
73.00
-53.20%
Consensus Target
165.33
5.99%
Highest Target
205.00
31.42%

The consensus 1-year price target stands at 165.33, with estimates ranging from a low of 73.00 to a high of 205.00.

Analyst Consensus Analysis

Upside Potential

+6.0%

Moderate upside. Analysts expect positive returns but with limited margin of safety. Consider entry timing.

Analyst Agreement

79.8% spread

High uncertainty. Very wide target spread indicates significant disagreement among analystsโ€”major valuation uncertainty or transformation underway.

Risk-Reward Profile

0.59x

Unfavorable risk-reward. Downside risk exceeds upside potential. Consider defensive positioning or alternative opportunities.

Analyst Conviction

Low

High uncertainty: Wide dispersion indicates analysts struggle to agree on valuationโ€”proceed with caution and independent analysis.

Market Sentiment Insight

Extreme uncertainty: Massive dispersion in price targets reflects fundamental disagreement on business trajectory. This could signal transformation, disruption, or complex valuationโ€”requires deep sector expertise and contrarian mindset.

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Revolution Medicines, Inc. Forward Estimates of Revenue

RVMD ยท NASDAQ
Latest Revenue
0.00
FY 2025
Avg Estimate
30.15M
FY 2026
Estimate Range
2.81M - 73.97M
Analyst Spread

Forward Growth Analysis

Analyst Coverage12 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread236%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

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Revolution Medicines, Inc. Forward Estimates of Net Income

RVMD ยท NASDAQ
Latest Net Income
-1.13B
FY 2025
Avg Estimate
-1.23B
FY 2026
Estimate Range
-1.33B - -258.79M
Analyst Spread

Forward Growth Analysis

Projected Growth-8.9%

Declining expectations indicate headwindsโ€”investigate whether temporary or structural issues.

Analyst Coverage12 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread87%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

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Revolution Medicines, Inc. Forward Estimates of EPS

RVMD ยท NASDAQ
Latest EPS
-5.95
FY 2025
Avg Estimate
$-6.36
FY 2026
Estimate Range
$-7.91 - $-1.54
Analyst Spread

Forward Growth Analysis

Projected Growth-6.9%

Declining expectations indicate headwindsโ€”investigate whether temporary or structural issues.

Analyst Coverage15 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread100%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

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Revolution Medicines, Inc. Forward Estimates of EBIT

RVMD ยท NASDAQ
Latest EBIT
-1.11B
FY 2025
Avg Estimate
-18.09M
FY 2026
Estimate Range
-44.38M - -1.69M
Analyst Spread

Forward Growth Analysis

Projected Growth+98.4%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage12 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread236%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

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Revolution Medicines, Inc. Forward Estimates of EBITDA

RVMD ยท NASDAQ
Latest EBITDA
-1.09B
FY 2025
Avg Estimate
-18.09M
FY 2026
Estimate Range
-44.38M - -1.69M
Analyst Spread

Forward Growth Analysis

Projected Growth+98.3%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage12 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread236%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

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Revolution Medicines, Inc. Forward Estimates of SG&A Expense

RVMD ยท NASDAQ
Latest SG&A Expense
187.13M
FY 2025
Avg Estimate
54.50M
FY 2026
Estimate Range
5.09M - 133.71M
Analyst Spread

Forward Growth Analysis

Projected Growth-70.9%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage12 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread236%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

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Revolution Medicines, Inc. Insider Positioning

RVMD ยท NASDAQ

During the last 12 months, insiders have sold $44.99M worth of RVMD shares, with no buying activity reported.

3 Months

Bought

0

0.00

Sold

155.7K

21.64M

Net Activity

-21.6M

-$21.64M

3-6 Months

Bought

0

0.00

Sold

86.2K

7.90M

Net Activity

-7.9M

-$7.90M

6-9 Months

Bought

0

0.00

Sold

239.4K

13.87M

Net Activity

-13.9M

-$13.87M

9-12 Months

Bought

0

0.00

Sold

39.4K

1.57M

Net Activity

-1.6M

-$1.57M

Top Buyers

No buying activity

Top Sellers

1
GMA

Goldsmith Mark A

Director, Officer: See Remarks

285.9K sharesโ€ข9 transactions

$29.31M

2
HMA

Horn Margaret A

Officer: Chief Operating Officer

70.8K sharesโ€ข5 transactions

$6.50M

3
KSM

Kelsey Stephen Michael

Officer: See Remarks

101.7K sharesโ€ข7 transactions

$5.03M

4
AJ

Anders Jack

Officer: Chief Financial Officer

35.8K sharesโ€ข8 transactions

$2.15M

5
CJ

Cislini Jeff

Officer: General Counsel

14.0K sharesโ€ข8 transactions

$919K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $44.99M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$21.64M

Heavy recent selling activity. Recent insider sales notably exceed purchasesโ€”may warrant investigation into company developments.

Insider Participation

High Selling

5 insider sellers vs. 0 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.