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Rapport Therapeutics, Inc. Common Stock

RAPP·NASDAQ

$37.65

+7.9%
HealthcareBiotechnology

Rapport Therapeutics, Inc., operates as a clinical-stage biopharmaceutical company that focuses on the discovery and development of transformational small molecule medicines for patients suffering from central nervous system (CNS) disorders. Its lead product candidate is receptor associated protein (RAP)-219, an investigational small molecule that is designed to inhibit TARPy8-containing AMPARs with picomolar affinity for the treatment of focal epilepsy and other CNS disorders, including peripheral neuropathic pain and bipolar disorder. The company also develops RAP-199, a TARPy8 targeted molecule with differentiated chemical and pharmacokinetic properties; and nicotinic acetylcholine receptor (nAChR) programs, such as a6 nAChR to treat chronic pain and a9a10 nAChR for the treatment of hearing disorders. The company was formerly known as Precision Neuroscience NewCo, Inc. and changed its name to Rapport Therapeutics, Inc. in October 2022. Rapport Therapeutics, Inc. was incorporated in 2022 and is based in Boston, Massachusetts.

At a Glance

Live Snapshot
Market Cap$1.37B
EPS-2.8600
P/E Ratio-13.17
Earnings Date08/06/2026
-25.21%
Return on Invested Capital
-7%
3Y-27.0%
5Y-27.0%
10Y-27.0%
-23.00%
Return on Equity
-10%
3Y-58.0%
5Y-58.0%
10Y-58.0%
-21.76%
Return on Assets
-13%
3Y-35.0%
5Y-35.0%
10Y-35.0%
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Rapport Therapeutics, Inc. Common Stock Management Team

RAPP · NASDAQ
MS

Mr. Swamy Yeleswaram Ph.D.

Chief Development Officer

Born 1964(Age 62)
male
MA

Mr. Abraham N. Ceesay M.B.A.

Chief Executive Officer, President, Treasurer & Director

Compensation

$891,283

Born 1978(Age 48)
male
DT

Dr. Troy A. Ignelzi

Chief Financial Officer

Compensation

$675,536

Born 1968(Age 58)
MK

Ms. Karina Chmielewski

Chief Information Officer & Head of Operations

female
MC

Ms. Cheryl Gault

Chief Operating Officer

Compensation

$281,110

Born 1980(Age 46)
female
MK

Ms. Kathleen A. Wilkinson

Chief People Officer

Born 1972(Age 54)
female
MD

Mr. David Bredt M.D., Ph.D.

Founder & Chief Scientific Officer

Born 1966(Age 60)
male
DS

Dr. Steven M. Paul M.D.

Founder & Independent Chairman

Compensation

$28,795

Born 1951(Age 75)
MJ

Ms. Julie DiCarlo

Head of Communications & Investor Relations

female
DA

Dr. Arnold R. Gammaitoni Pharm.D.

Senior Vice President of Medical Affairs

Born 1967(Age 59)
r

Rapport Therapeutics, Inc. Common Stock Insider Positioning

RAPP · NASDAQ

During the last 12 months, insiders have sold $37.94M worth of RAPP shares, with no buying activity reported.

3 Months

Bought

0

0.00

Sold

912.4K

36.41M

Net Activity

-36.4M

-$36.41M

3-6 Months

Bought

0

0.00

Sold

39.3K

1.12M

Net Activity

-1.1M

-$1.12M

6-9 Months

Bought

0

0.00

Sold

15.2K

410.59K

Net Activity

-411K

-$411K

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

No buying activity

Top Sellers

1
TRVVL

Third Rock Ventures V, L.P.

10 Percent Owner

854.7K shares5 transactions

$34.39M

2
YK

Yeleswaram Krishnaswamy

Officer: Chief Development Officer

53.4K shares7 transactions

$1.91M

3
BD

Bredt David

Officer: Chief Scientific Officer

30.0K shares4 transactions

$842K

4
GC

Gault Cheryl

Officer: Chief Operating Officer

14.2K shares3 transactions

$410K

5
CA

Ceesay Abraham

Director, Officer: Chief Executive Officer

14.6K shares4 transactions

$395K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $37.94M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$36.41M

Heavy recent selling activity. Recent insider sales notably exceed purchases—may warrant investigation into company developments.

Insider Participation

High Selling

5 insider sellers vs. 0 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.

SEC Filings

RAPP - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

April 23, 2026
June 10, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 24, 2025
June 17, 2025
2025
Showing 1 to 2 of 2 filings