uniQure N.V.

uniQure N.V.

QUREยทNASDAQ

$29.88

+12%
HealthcareBiotechnology

uniQure N.V., a gene therapy company, engages in the development of treatments for patients suffering from genetic and other devastating diseases. Its lead program is Etranacogene dezaparvovec (AMT-061), which is in Phase III HOPE-B pivotal trial for the treatment of hemophilia B. The company also engages in developing AMT-130, a gene therapy that is in Phase I/II clinical study for the treatment of Huntington's disease; AMT-060, which is in Phase I/II clinical trial for the treatment of hemophilia B; AMT-210, a product candidate for the treatment of Parkinson's disease; AMT-260 for temporal lobe epilepsy; AMT-240, a preclinical product candidate for the treatment of autosomal dominant Alzheimer's disease; and AMT-161 for the treatment of amyotrophic lateral sclerosis. uniQure N.V. was founded in 1998 and is headquartered in Amsterdam, the Netherlands.

At a Glance

Live Snapshot
Market Cap$1.88B
EPS-3.4600
P/E Ratio-8.64
Earnings Date08/04/2026
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uniQure N.V. Street Expectations Map

QURE ยท NASDAQ

Wall Street analysts project that QURE stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 35.44, with estimates ranging from a low of 10.00 to a high of 60.00.

Lowest Target
10.00
-66.53%
Consensus Target
35.44
18.61%
Highest Target
60.00
100.80%

The consensus 1-year price target stands at 35.44, with estimates ranging from a low of 10.00 to a high of 60.00.

Analyst Consensus Analysis

Upside Potential

+18.6%

Strong upside potential. Consensus indicates attractive return opportunity with favorable risk-reward profile.

Analyst Agreement

141.1% spread

High uncertainty. Very wide target spread indicates significant disagreement among analystsโ€”major valuation uncertainty or transformation underway.

Risk-Reward Profile

1.52x

Balanced risk-reward. Upside and downside potential relatively symmetric. Suitable for moderate risk tolerance with conviction in thesis.

Analyst Conviction

Low

High uncertainty: Wide dispersion indicates analysts struggle to agree on valuationโ€”proceed with caution and independent analysis.

Market Sentiment Insight

High risk, high reward: Substantial upside potential exists, but wide analyst disagreement signals execution risk or unclear catalysts. Thorough due diligence essential before committing capital.

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uniQure N.V. Forward Estimates of Revenue

QURE ยท NASDAQ
Latest Revenue
16.10M
FY 2025
Avg Estimate
20.76M
FY 2026
Estimate Range
14.05M - 28.78M
Analyst Spread

Forward Growth Analysis

Projected Growth+28.9%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage9 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread71%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

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uniQure N.V. Forward Estimates of Net Income

QURE ยท NASDAQ
Latest Net Income
-198.97M
FY 2025
Avg Estimate
-200.48M
FY 2026
Estimate Range
-241.24M - -180.93M
Analyst Spread

Forward Growth Analysis

Projected Growth-0.8%

Declining expectations indicate headwindsโ€”investigate whether temporary or structural issues.

Analyst Coverage9 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread30%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

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uniQure N.V. Forward Estimates of EPS

QURE ยท NASDAQ
Latest EPS
-3.46
FY 2025
Avg Estimate
$-3.51
FY 2026
Estimate Range
$-4.20 - $-3.15
Analyst Spread

Forward Growth Analysis

Projected Growth-1.4%

Declining expectations indicate headwindsโ€”investigate whether temporary or structural issues.

Analyst Coverage9 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread30%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

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uniQure N.V. Forward Estimates of EBIT

QURE ยท NASDAQ
Latest EBIT
-131.35M
FY 2025
Avg Estimate
-14.14M
FY 2026
Estimate Range
-19.60M - -9.57M
Analyst Spread

Forward Growth Analysis

Projected Growth+89.2%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage9 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread71%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

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uniQure N.V. Forward Estimates of EBITDA

QURE ยท NASDAQ
Latest EBITDA
-116.59M
FY 2025
Avg Estimate
-14.08M
FY 2026
Estimate Range
-19.52M - -9.53M
Analyst Spread

Forward Growth Analysis

Projected Growth+87.9%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage9 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread71%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

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uniQure N.V. Forward Estimates of SG&A Expense

QURE ยท NASDAQ
Latest SG&A Expense
65.34M
FY 2025
Avg Estimate
46.34M
FY 2026
Estimate Range
31.36M - 64.26M
Analyst Spread

Forward Growth Analysis

Projected Growth-29.1%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage9 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread71%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

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uniQure N.V. Insider Positioning

QURE ยท NASDAQ

During the last 12 months, insiders have sold $628K worth of QURE shares, with no buying activity reported.

3 Months

Bought

0

0.00

Sold

25.0K

627.50K

Net Activity

-628K

-$628K

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

No buying activity

Top Sellers

1
AW

Abi-Saab Walid

Officer: Chief Medical Officer

25.0K sharesโ€ข1 transactions

$628K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $628K net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$628K

Heavy recent selling activity. Recent insider sales notably exceed purchasesโ€”may warrant investigation into company developments.

Insider Participation

High Selling

1 insider sellers vs. 0 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Persistent selling pressure: Consistent insider selling with weak buy/sell ratio suggests insiders may be capitalizing on current valuation. Exercise caution and review recent earnings quality and management commentary.