Q32 Bio Inc.

Q32 Bio Inc.

QTTB·NASDAQ

$12.64

+23%
HealthcareBiotechnology

Q32 Bio Inc., a clinical-stage biotechnology company, develops biologic therapeutics to restore healthy immune balance in patients with autoimmune and inflammatory diseases driven by pathological immune dysfunction in the United States. Its lead product candidate is ADX-097, a humanized anti-C3d monoclonal antibody fusion protein to restore complement regulation, which has completed Phase I clinical trial for the treatment of renal and other complement-mediated diseases of high unmet need, including lupus nephritis, immunoglobulin A nephropathy, complement component 3 glomerulopathy, and anti-neutrophil cytoplasmic antibody-associated vasculitis. The company is also developing Bempikibart (ADX-914), a fully human anti–interleukin-7 receptor alpha antagonist monoclonal antibody designed to re-regulate adaptive immune function by blocking signaling mediated by interleukin-7 and thymic stromal lymphopoietin that is Phase II clinical trial for the treatment of atopic dermatitis and alopecia areata. Q32 Bio Inc. was formerly known as AdMIRx Inc. and changed its name to Q32 Bio Inc. in April 2020. The company was founded in 2017 and is based in Waltham, Massachusetts.

At a Glance

Live Snapshot
Market Cap$161.49M
EPS2.4200
P/E Ratio1.37
Earnings Date08/05/2026
29.47%
Return on Invested Capital
-135%
3Y-128.0%
5Y-155.0%
10Y-123.0%
70.98%
Return on Equity
-108%
3Y-395.0%
5Y-208.0%
10Y-166.0%
48.27%
Return on Assets
-193%
3Y-170.0%
5Y-199.0%
10Y-185.0%
Q32 Bio Inc.

Q32 Bio Inc. Management Team

QTTB · NASDAQ
JP

Jodie Pope Morrison

Chief Executive Officer & Director

Compensation

$860,740

Born 1976(Age 50)
female
LH

Lee H. Kalowski

Chief Financial Officer & President

Compensation

$750,793

Born 1981(Age 45)
male
SF

Saul Fink

Chief Technology Officer

SV

Shelia Violette

Co-founder, Chief Scientific Officer & President of Research

Compensation

$619,930

Born 1961(Age 65)
MM

Maria Marzilli

Executive Vice President of Corporate Strategy & Program Operations

female
AS

Adrien Sipos

Interim Chief Medical Officer

DA

David Appugliese

Senior Vice President & Head of People

male
qttb

Q32 Bio Inc. Insider Positioning

QTTB · NASDAQ

During the last 12 months, insiders have purchased $10.00M and sold $217K worth of QTTB shares, resulting in $9.78M of net buying activity.

3 Months

Bought

1.3M

10.00M

Sold

0

0.00

Net Activity

+10.0M

+$10.00M

3-6 Months

Bought

0

0.00

Sold

16.7K

75.42K

Net Activity

-75K

-$75K

6-9 Months

Bought

0

0.00

Sold

31.6K

109.27K

Net Activity

-109K

-$109K

9-12 Months

Bought

0

0.00

Sold

17.7K

31.92K

Net Activity

-32K

-$32K

Top Buyers

1
XD

Xu Diyong

Director, 10 Percent Owner:

1.3M shares1 transactions

$10.00M

Top Sellers

1
MJP

Morrison Jodie Pope

Director, Officer: Ceo

42.9K shares3 transactions

$141K

2
KL

Kalowski Lee

Officer: Cfo And President

17.3K shares3 transactions

$57K

3
VSM

Violette Shelia M.

Officer: Chief Scientific Officer

5.8K shares2 transactions

$18K

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $9.78M net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

46.17:1

Exceptional buy/sell ratio. Buying dramatically outweighs selling—one of the strongest possible insider signals.

Recent Trend (3 Months)

$10.00M

Very strong recent buying momentum. Recent insider purchases significantly outpace sales, suggesting near-term optimism.

Insider Participation

High Selling

3 insider sellers vs. 1 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Sustained buying momentum: Consistent net buying over multiple quarters suggests insiders maintain conviction in the company's prospects. This is particularly meaningful if buying continued through market volatility.

SEC Filings

QTTB - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

April 30, 2026
June 12, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 29, 2025
June 13, 2025
2025
DEF 14A

DEF 14A 2023

N/A

April 28, 2023
June 14, 2023
2023
DEF 14A

DEF 14A 2022

N/A

April 29, 2022
June 15, 2022
2022
DEF 14A

DEF 14A 2021

N/A

April 29, 2021
June 17, 2021
2021
DEF 14A

DEF 14A 2020

N/A

April 28, 2020
June 10, 2020
2020
DEF 14A

DEF 14A 2019

N/A

April 25, 2019
June 06, 2019
2019
Showing 1 to 7 of 7 filings