Prime Medicine, Inc.

Prime Medicine, Inc.

PRMEยทNASDAQ

$3.14

-2.2%
HealthcareBiotechnology

Prime Medicine, Inc., a biotechnology company, delivers genetic therapies to address diseases by deploying gene editing technology. It offers Prime Editors with a Prime Editor protein, comprising a fusion between a Cas protein and a reverse transcriptase enzyme; and a pegRNA, which targets the Prime Editor to a specific genomic location and provides a template for making the desired edit to the target DNA sequence. The company was incorporated in 2019 and is headquartered in Cambridge, Massachusetts.

At a Glance

Live Snapshot
Market Cap$567.14M
EPS-1.3500
P/E Ratio-2.33
Earnings Date08/06/2026
3Y+23.0%
5Y+2832.0%
10Y+12086.0%
3Y+131.0%
5Y+10141.0%
10Y-
3Y-17.0%
5Y+334.0%
10Y+1418.0%
PRME

Prime Medicine, Inc. Cash Conversion Engine

PRME ยท NASDAQ
Net Income-201.14M
Depreciation & Amortization5.38M
Stock-Based Compensation29.27M
Change in Working Capital-5.34M
Others9.27M
Capital Expenditures-4.53M
Free Cash Flow-167.09M

Cash Flow Quality Analysis

FCF Conversion Rate

83.1%

Strong cash conversion. Most reported earnings translate into actual cash flow, suggesting solid fundamentals.

CapEx Intensity

-2.8%

Asset-light business model. Low capital requirements leave more cash available for shareholders and growth investments.

FCF Growth Trend

-28.4%

Significant FCF decline raises concerns. Urgent review needed of operational performance and capital allocation.

Working Capital Impact

-$5.34M

Minimal working capital impact on FCF. Changes in operating assets and liabilities well-managed.

Cash Flow Quality Insight

Working capital strain: Significant cash tied up in operations. Monitor receivables collection, inventory turns, and payment terms to optimize cash conversion cycle.

Prime Medicine, Inc. Cash Flow Statement

PRME โ€ข NASDAQ

Prime Medicine, Inc. Cash Flow StatementDec 2025Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020Dec 2019
OPERATING ACTIVITIES
-201.1M
-195.9M
-198.1M
-121.8M
-165.4M
-3.4M
-2.5M
5.4M
6.1M
4.7M
2.2M
568K
43K
0.0
0.0
0.0
-279K
-964K
-624K
1.9M
0.0
29.3M
26.1M
13.9M
6.5M
1.7M
391K
0.0
9.3M
9.7M
11.8M
17.7M
98.4M
-4.6M
703K
(0.0)
(0.0)
(0.0)
(141K)
(0.0)
(0.0)
(0.0)
-5.3M
31.1M
2.6M
-35.4M
31.2M
164K
492K
-162.6M
-122.9M
-165.4M
-131.8M
-34.1M
-5.5M
-1.3M
INVESTING ACTIVITIES
-4.5M
-7.3M
-8.7M
-16.1M
-4.2M
-639K
(0.0)
-205.4M
-129.4M
-105M
-123.3M
-82M
(0.0)
(0.0)
101.2M
204.2M
132.6M
93M
13M
0.0
0.0
0.0
1M
-170K
-665K
-496K
-423K
0.0
-108.8M
(68.5M)
(18.7M)
-47.1M
-73.6M
-1.1M
(0.0)
FINANCING ACTIVITIES
139.5M
170.1M
655K
185.3M
0.0
0.0
0.0
12M
25.7M
0.0
-3.8M
-1.1M
-20K
10M
151.5M
195.9M
655K
181.5M
269.3M
34.9M
10M
CASH FLOW SUMMARY
-119.8M
141.5M
-146M
2.6M
161.6M
28.3M
8.6M
196.5M
55.1M
201.1M
198.5M
37M
8.6M
0.0
76.7M
196.5M
55.1M
201.1M
198.5M
37M
8.6M
-167.1M
-130.2M
-174.1M
-147.9M
-38.2M
-6.2M
-1.3M

SEC Filings

PRME - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
10-Q

10-Q 2026 Q1

Q1

May 07, 2026
March 31, 2026
2026
8-K

8-K 2026

N/A

May 07, 2026
May 07, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 23, 2026
December 31, 2025
2025
8-K

8-K 2026

N/A

April 16, 2026
April 07, 2026
2026
10-K

10-K 2025 FY

FY

March 03, 2026
December 31, 2025
2025
8-K

8-K 2026

N/A

March 03, 2026
March 03, 2026
2026
8-K

8-K 2026

N/A

January 12, 2026
January 12, 2026
2026
8-K

8-K 2025

N/A

November 07, 2025
November 07, 2025
2025
10-Q

10-Q 2025 Q3

Q3

November 07, 2025
September 30, 2025
2025
8-K

8-K 2025

N/A

September 08, 2025
September 08, 2025
2025
Showing 1 to 10 of 65 filings