ORIC Pharmaceuticals, Inc.

ORIC Pharmaceuticals, Inc.

ORIC·NASDAQ

$8.04

+5.6%
HealthcareBiotechnology

ORIC Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, discovers and develops therapies for treatment of cancers in the United States. Its clinical stage product candidates include ORIC-533, an orally bioavailable small molecule inhibitor of CD73 being developed for resistance to chemotherapy- and immunotherapy-based treatment regimens; ORIC-944, an allosteric inhibitor of the polycomb repressive complex 2 for prostate cancer; and ORIC-114, a brain penetrant orally bioavailable irreversible inhibitor designed to selectively target epidermal growth factor receptor and human epidermal growth factor receptor 2 with high potency towards exon 20 insertion mutations. The company is also developing multiple discovery stage precision medicines targeting other cancer resistance mechanisms. It has a license and collaboration agreement with Voronoi Inc.; and a license agreement with Mirati Therapeutics, Inc. The company was incorporated in 2014 and is headquartered in South San Francisco, California.

At a Glance

Live Snapshot
Market Cap$832.80M
EPS-1.4700
P/E Ratio-5.47
Earnings Date08/06/2026
-36.30%
Return on Invested Capital
-36%
3Y-6.0%
5Y+42.0%
10Y-56.0%
-33.68%
Return on Equity
-36%
3Y-16.0%
5Y+32.0%
10Y-61.0%
-31.50%
Return on Assets
-32%
3Y-12.0%
5Y+28.0%
10Y-57.0%
ORIC Pharmaceuticals, Inc.

ORIC Pharmaceuticals, Inc. Management Team

ORIC · NASDAQ
MD

Mr. Dominic G. Piscitelli CPA, M.B.A.

Chief Financial Officer

Compensation

$684,155

Born 1975(Age 51)
male
DP

Dr. Pratik S. Multani M.D., M.S.

Chief Medical Officer

Compensation

$735,587

Born 1967(Age 59)
DL

Dr. Lori Sickels Friedman Ph.D.

Chief Scientific Officer

Born 1964(Age 62)
DC

Dr. Charles L. Sawyers B.A., M.D., Ph.D.

Co-Founder & Member of Scientific Advisory Board

Born 1959(Age 67)
DS

Dr. Scott W. Lowe Ph.D.

Co-Founder & Member of Scientific Advisory Board

DR

Dr. Richard A. Heyman Ph.D.

Co-Founder, Independent Chairman & Member of Scientific Advisory Board

Compensation

$100,000

Born 1957(Age 69)
DE

Dr. Edna Chow Maneval Ph.D.

Executive Vice President of Clinical Development

Born 1961(Age 65)
DC

Dr. Christian V. Kuhlen Esq., J.D., M.D.

General Counsel

Born 1973(Age 53)
DJ

Dr. Jacob M. Chacko M.B.A., M.D.

President, Chief Executive Officer & Director

Compensation

$1,039,037

Born 1979(Age 47)
MD

Mr. Daniel Iazzetti

Vice President & Head of People

male
oric

ORIC Pharmaceuticals, Inc. Insider Positioning

ORIC · NASDAQ

During the last 12 months, insiders have sold $1.29M worth of ORIC shares, with no buying activity reported.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

0

0.00

Sold

110.0K

1.24M

Net Activity

-1.2M

-$1.24M

6-9 Months

Bought

0

0.00

Sold

11.0K

47.96K

Net Activity

-48K

-$48K

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

No buying activity

Top Sellers

1
PD

Piscitelli Dominic

Officer: Chief Financial Officer

73.7K shares3 transactions

$848K

2
CJ

Chacko Jacob

Director, Officer: President And Ceo

33.4K shares1 transactions

$302K

3
MPS

Multani Pratik S

Officer: Chief Medical Officer

10.7K shares1 transactions

$97K

4
HRA

Heyman Richard A.

Director

3.2K shares1 transactions

$38K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $1.29M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Insider Participation

High Selling

4 insider sellers vs. 0 buyers. Widespread selling across multiple insiders may signal concerns.

SEC Filings

ORIC - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

April 28, 2026
June 18, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 23, 2025
June 11, 2025
2025
DEF 14A

DEF 14A 2024

N/A

April 24, 2024
June 12, 2024
2024
DEF 14A

DEF 14A 2023

N/A

April 26, 2023
June 14, 2023
2023
DEF 14A

DEF 14A 2022

N/A

April 27, 2022
June 17, 2022
2022
DEF 14A

DEF 14A 2021

N/A

April 26, 2021
June 16, 2021
2021
Showing 1 to 6 of 6 filings