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BeOne Medicines Ltd.

ONC·NASDAQ

$279.00

+1.6%
HealthcareMedical - Pharmaceuticals

BeOne Medicines, formerly known as BeiGene, is a global oncology company focused on discovering, developing, and commercializing innovative cancer therapies. Founded in 2010 and headquartered in Cambridge, Massachusetts—with operations spanning over 45 countries across six continents—the company rebranded as BeOne in late 2024 and redomiciled to Basel, Switzerland in 2025. BeOne has established itself as a leader in immuno-oncology and targeted therapies, with key assets including Tevimbra (tislelizumab), a PD-1 monoclonal antibody approved for multiple cancer indications globally, and Brukinsa (zanubrutinib), a Bruton's tyrosine kinase (BTK) inhibitor that surpassed $1.3 billion in annual sales and is approved in major markets such as the U.S., Europe, and China. The company’s strategy combines internal R&D with the development of assets sourced from external partnerships, driving a robust pipeline across hematologic malignancies and solid tumors.

At a Glance

Live Snapshot
Market Cap$29.81B
EPS34.1900
P/E Ratio8.16
Earnings Date08/05/2026
4.74%
Return on Invested Capital
-138%
3Y-114.0%
5Y-114.0%
10Y-115.0%
6.58%
Return on Equity
-134%
3Y-114.0%
5Y-116.0%
10Y-119.0%
3.50%
Return on Assets
-132%
3Y-111.0%
5Y-112.0%
10Y-112.0%
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BeOne Medicines Ltd. Management Team

ONC · NASDAQ
AR

Aaron Rosenberg

Chief Financial Officer

Compensation

$1,928,439

Born 1977(Age 49)
male
MD

Marcello Damiani

Chief Technology Officer

Born 1970(Age 56)
male
XW

Xiaodong Wang

Co-Chairman of Scientific Advisory Board, Non-Executive Director & Co-Founder

Compensation

$4,249,950

Born 1963(Age 63)
JV

John V. Oyler

Co-Founder, Executive Chairman & Chief Executive Officer

Compensation

$2,836,747

Born 1968(Age 58)
male
CL

Chan Lee

General Counsel & Senior Vice President

Compensation

$1,076,400

Born 1968(Age 58)
male
WL

Wang Lai

Global Head of Research & Development

Compensation

$1,202,653

Born 1977(Age 49)
male
LH

Liza Heapes

Head of Investor Relations

female
XW

Xiaobin Wu

President, Chief Operating Officer & GM of China

Compensation

$1,838,195

Born 1962(Age 64)
ED

Eleanor Duff

Senior VP & Head of Corporate Communications

female
TB

Titus Ball

Vice President & Chief Accounting Officer

Born 1973(Age 53)
male
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BeOne Medicines Ltd. Insider Positioning

ONC · NASDAQ

During the last 12 months, insiders have sold $1.56M worth of ONC shares, with no buying activity reported.

3 Months

Bought

0

0.00

Sold

4.4K

571.21K

Net Activity

-571K

-$571K

3-6 Months

Bought

0

0.00

Sold

3.1K

992.01K

Net Activity

-992K

-$992K

6-9 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

No buying activity

Top Sellers

1
LCH

Lee Chan Henry

Officer: Svp, General Counsel

2.3K shares5 transactions

$761K

2
OJ

Oyler John

Director, Officer: Chief Executive Officer

1.8K shares1 transactions

$540K

3
DM

Dugan Margaret

Director

212 shares1 transactions

$66K

4
SC(D

Sanders Corazon (Corsee) D.

Director

212 shares1 transactions

$66K

5
RA

Riva Alessandro

Director

212 shares1 transactions

$66K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $1.56M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$571K

Heavy recent selling activity. Recent insider sales notably exceed purchases—may warrant investigation into company developments.

Insider Participation

High Selling

5 insider sellers vs. 0 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.

SEC Filings

ONC - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

April 28, 2026
June 11, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 07, 2025
May 21, 2025
2025
DEF 14A

DEF 14A 2024

N/A

April 26, 2024
June 05, 2024
2024
DEF 14A

DEF 14A

N/A

April 27, 2023
April 27, 2023
 
DEF 14A

DEF 14A 2022

N/A

April 29, 2022
June 22, 2022
2022
DEF 14A

DEF 14A 2021

N/A

April 30, 2021
June 16, 2021
2021
DEF 14A

DEF 14A 2020

N/A

October 09, 2020
November 20, 2020
2020
DEF 14A

DEF 14A 2020

N/A

April 28, 2020
June 17, 2020
2020
DEF 14A

DEF 14A 2019

N/A

November 29, 2019
December 27, 2019
2019
DEF 14A

DEF 14A 2019

N/A

April 29, 2019
June 05, 2019
2019
Showing 1 to 10 of 13 filings