Nuvalent, Inc.

Nuvalent, Inc.

NUVLยทNASDAQ

$90.18

-1.6%
HealthcareBiotechnology

Nuvalent, Inc., a clinical stage biopharmaceutical company, develops therapies for patients with cancer. Its lead product candidates are NVL-520, a brain-penetrant ROS1-selective inhibitor to inhibit ROS1 fusions that express the normal ROS1 kinase domain without any drug-resistant mutations and remain active in the presence of mutations conferring resistance to approved and investigational ROS1 inhibitors, which is under Phase I development; and NVL-655, a brain-penetrant ALK-selective inhibitor, to address the clinical challenges of emergent treatment resistance, central nervous system-related adverse events, and brain metastases that might limit the use of first-, second-, and third-generation ALK inhibitors that is under Phase I/II clinical trial. The company was incorporated in 2017 and is headquartered in Cambridge, Massachusetts.

At a Glance

Live Snapshot
Market Cap$6.63B
EPS-5.8500
P/E Ratio-15.42
Earnings Date08/06/2026
nuvl

Nuvalent, Inc. Street Expectations Map

NUVL ยท NASDAQ

Wall Street analysts project that NUVL stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 177.00, with estimates ranging from a low of 165.00 to a high of 189.00.

Lowest Target
165.00
82.97%
Consensus Target
177.00
96.27%
Highest Target
189.00
109.58%

The consensus 1-year price target stands at 177.00, with estimates ranging from a low of 165.00 to a high of 189.00.

Analyst Consensus Analysis

Upside Potential

+96.3%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

13.6% spread

High analyst agreement. Narrow target range indicates strong consensus on valuation, suggesting clear investment thesis and predictable outlook.

Analyst Conviction

Very High

Strong buy conviction: High upside with tight consensus suggests compelling investment opportunity backed by analyst confidence.

Market Sentiment Insight

Rare opportunity: Exceptional upside potential with strong analyst consensus creates a compelling setup. The combination of significant price target premium and tight agreement suggests high-conviction undervaluation that may attract institutional capital.

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Nuvalent, Inc. Forward Estimates of Revenue

NUVL ยท NASDAQ
Latest Revenue
0.00
FY 2025
Avg Estimate
11.67M
FY 2026
Estimate Range
518.65K - 28.72M
Analyst Spread

Forward Growth Analysis

Analyst Coverage15 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread242%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

nuvl

Nuvalent, Inc. Forward Estimates of Net Income

NUVL ยท NASDAQ
Latest Net Income
-425.38M
FY 2025
Avg Estimate
-453.95M
FY 2026
Estimate Range
-459.72M - -370.95M
Analyst Spread

Forward Growth Analysis

Projected Growth-6.7%

Declining expectations indicate headwindsโ€”investigate whether temporary or structural issues.

Analyst Coverage15 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread20%

Reasonable estimate spread indicates general agreement with normal forecast variance.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

nuvl

Nuvalent, Inc. Forward Estimates of EPS

NUVL ยท NASDAQ
Latest EPS
-5.85
FY 2025
Avg Estimate
$-5.70
FY 2026
Estimate Range
$-6.32 - $-5.10
Analyst Spread

Forward Growth Analysis

Projected Growth+2.6%

Flat growth suggests market maturity or near-term challenges offsetting expansion efforts.

Analyst Coverage14 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread21%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

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Nuvalent, Inc. Forward Estimates of EBIT

NUVL ยท NASDAQ
Latest EBIT
-424.79M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage15 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

Well-supported growth expectations: Strong analyst coverage combined with positive growth projections provides confidence in forward outlook.

nuvl

Nuvalent, Inc. Forward Estimates of EBITDA

NUVL ยท NASDAQ
Latest EBITDA
-10.48M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage15 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

Well-supported growth expectations: Strong analyst coverage combined with positive growth projections provides confidence in forward outlook.

nuvl

Nuvalent, Inc. Forward Estimates of SG&A Expense

NUVL ยท NASDAQ
Latest SG&A Expense
107.34M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth-100.0%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage15 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

nuvl

Nuvalent, Inc. Insider Positioning

NUVL ยท NASDAQ

During the last 12 months, insiders have sold $24.78M worth of NUVL shares, with no buying activity reported.

3 Months

Bought

0

0.00

Sold

72.2K

7.19M

Net Activity

-7.2M

-$7.19M

3-6 Months

Bought

0

0.00

Sold

25.7K

2.80M

Net Activity

-2.8M

-$2.80M

6-9 Months

Bought

0

0.00

Sold

112.1K

10.23M

Net Activity

-10.2M

-$10.23M

9-12 Months

Bought

0

0.00

Sold

56.5K

4.57M

Net Activity

-4.6M

-$4.57M

Top Buyers

No buying activity

Top Sellers

1
BA

Balcom Alexandra

Officer: Chief Financial Officer

84.7K sharesโ€ข15 transactions

$7.45M

2
PHE

Pelish Henry E.

Officer: Chief Scientific Officer

69.8K sharesโ€ข13 transactions

$6.26M

3
MDA

Miller Deborah Ann

Officer: Chief Legal Officer

55.9K sharesโ€ข9 transactions

$5.56M

4
PJR

Porter James Richard

Director, Officer: President And Ceo

29.8K sharesโ€ข8 transactions

$2.94M

5
SM

Shair Matthew

Director

13.6K sharesโ€ข3 transactions

$1.36M

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $24.78M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$7.19M

Heavy recent selling activity. Recent insider sales notably exceed purchasesโ€”may warrant investigation into company developments.

Insider Participation

High Selling

5 insider sellers vs. 0 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.