Nektar Therapeutics

Nektar Therapeutics

NKTRยทNASDAQ

$59.23

+1.1%
HealthcareBiotechnology

Nektar Therapeutics, a biopharmaceutical company, focuses on discovering and developing medicines in areas of unmet medical need in the United States and internationally. The company's products include Bempegaldesleukin, a CD122-preferential interleukin-2 (IL-2) pathway agonist, which is in phase 3 clinical trial to treat metastatic melanoma, renal cell carcinoma, muscle-invasive bladder cancer, squamous cell carcinoma of the head and neck, and adjuvant melanoma; phase 2 clinical trial for the treatment of renal cell carcinoma, non-small cell lung cancer, and urothelial cancer; phase 1/2A clinical trial to treat squamous cell carcinoma of the head and neck; phase 1/2 clinical trial for the treatment of solid tumors; and phase 1B clinical trial to treat COVID-19. It is also developing NKTR-358, a cytokine Treg stimulant that is in phase 2 clinical trial for the treatment of systemic lupus erythematosus and ulcerative colitis, as well as phase 1B clinical trial to treat atopic dermatitis and psoriasis; NKTR-255, an IL-15 receptor agonist, which is in phase 1/2 clinical trial for the treatment of non-Hodgkin's lymphoma and multiple myeloma, and head and neck cancer and colorectal cancer; and NKTR-262, a toll-like receptor agonist that is in phase 1/2 clinical trial to treat solid tumors, as well as various other drug candidates. The company has collaboration agreements with Takeda Pharmaceutical Company Ltd.; AstraZeneca AB; UCB Pharma S.A.; F. Hoffmann-La Roche Ltd; Bausch Health Companies Inc.; Pfizer Inc.; Amgen Inc.; UCB Pharma (Biogen); Bristol-Myers Squibb Company; Baxalta Incorporated; Eli Lilly and Company; Merck KGaA; and SFJ Pharmaceuticals, Inc. Nektar Therapeutics was incorporated in 1990 and is headquartered in San Francisco, California.

At a Glance

Live Snapshot
Market Cap$1.16B
EPS-9.7300
P/E Ratio-6.09
Earnings Date08/06/2026
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Nektar Therapeutics Street Expectations Map

NKTR ยท NASDAQ

Wall Street analysts project that NKTR stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 149.60, with estimates ranging from a low of 80.00 to a high of 192.00.

Lowest Target
80.00
35.07%
Consensus Target
149.60
152.57%
Highest Target
192.00
224.16%

The consensus 1-year price target stands at 149.60, with estimates ranging from a low of 80.00 to a high of 192.00.

Analyst Consensus Analysis

Upside Potential

+152.6%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

74.9% spread

High uncertainty. Very wide target spread indicates significant disagreement among analystsโ€”major valuation uncertainty or transformation underway.

Analyst Conviction

Low

High uncertainty: Wide dispersion indicates analysts struggle to agree on valuationโ€”proceed with caution and independent analysis.

Market Sentiment Insight

High risk, high reward: Substantial upside potential exists, but wide analyst disagreement signals execution risk or unclear catalysts. Thorough due diligence essential before committing capital.

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Nektar Therapeutics Forward Estimates of Revenue

NKTR ยท NASDAQ
Latest Revenue
55.23M
FY 2025
Avg Estimate
41.62M
FY 2026
Estimate Range
30.55M - 53.67M
Analyst Spread

Forward Growth Analysis

Projected Growth-24.6%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage7 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread56%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

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Nektar Therapeutics Forward Estimates of Net Income

NKTR ยท NASDAQ
Latest Net Income
-164.08M
FY 2025
Avg Estimate
-134.64M
FY 2026
Estimate Range
-158.54M - -110.73M
Analyst Spread

Forward Growth Analysis

Projected Growth+17.9%

Solid growth trajectory indicates healthy business performance and competitive positioning.

Analyst Coverage7 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread36%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

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Nektar Therapeutics Forward Estimates of EPS

NKTR ยท NASDAQ
Latest EPS
-9.73
FY 2025
Avg Estimate
$-9.79
FY 2026
Estimate Range
$-11.56 - $-8.08
Analyst Spread

Forward Growth Analysis

Projected Growth-0.6%

Declining expectations indicate headwindsโ€”investigate whether temporary or structural issues.

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread36%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

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Nektar Therapeutics Forward Estimates of EBIT

NKTR ยท NASDAQ
Latest EBIT
-130.77M
FY 2025
Avg Estimate
-41.00M
FY 2026
Estimate Range
-52.87M - -30.10M
Analyst Spread

Forward Growth Analysis

Projected Growth+68.6%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage7 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread56%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

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Nektar Therapeutics Forward Estimates of EBITDA

NKTR ยท NASDAQ
Latest EBITDA
-129.74M
FY 2025
Avg Estimate
-40.63M
FY 2026
Estimate Range
-52.40M - -29.83M
Analyst Spread

Forward Growth Analysis

Projected Growth+68.7%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage7 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread56%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

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Nektar Therapeutics Forward Estimates of SG&A Expense

NKTR ยท NASDAQ
Latest SG&A Expense
68.67M
FY 2025
Avg Estimate
37.72M
FY 2026
Estimate Range
27.69M - 48.65M
Analyst Spread

Forward Growth Analysis

Projected Growth-45.1%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage7 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread56%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

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Nektar Therapeutics Insider Positioning

NKTR ยท NASDAQ

During the last 12 months, insiders have purchased $2.28M and sold $536K worth of NKTR shares, resulting in $1.74M of net buying activity.

3 Months

Bought

0

0.00

Sold

643

42.12K

Net Activity

-42K

-$42K

3-6 Months

Bought

0

0.00

Sold

4.5K

181.95K

Net Activity

-182K

-$182K

6-9 Months

Bought

40.0K

2.28M

Sold

6.1K

311.63K

Net Activity

+2.0M

+$1.96M

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

1
GRS

Greer R Scott

Director

8.0K sharesโ€ข1 transactions

$455K

2
AJR

Ajer Jeffrey Robert

Director

8.0K sharesโ€ข1 transactions

$455K

3
BD

Brainard Diana

Director

8.0K sharesโ€ข1 transactions

$455K

4
CR

Chess Robert

Director

8.0K sharesโ€ข1 transactions

$455K

5
WRA

Whitfield Roy A

Director

8.0K sharesโ€ข1 transactions

$455K

Top Sellers

1
RHW

Robin Howard W

Director, Officer: President & Ceo

5.2K sharesโ€ข4 transactions

$275K

2
ZJ

Zalevsky Jonathan

Officer: Chief R&D Officer

5.4K sharesโ€ข4 transactions

$227K

3
WMA

Wilson Mark Andrew

Officer: Chief Legal Officer

630 sharesโ€ข1 transactions

$34K

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $1.74M net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

4.25:1

Exceptional buy/sell ratio. Buying dramatically outweighs sellingโ€”one of the strongest possible insider signals.

Recent Trend (3 Months)

$42K

Heavy recent selling activity. Recent insider sales notably exceed purchasesโ€”may warrant investigation into company developments.

Insider Participation

Moderate Buying

5 insider buyers vs. 3 sellers. More insiders buying than selling indicates positive sentiment.

Insider Activity Insight

Compelling insider conviction: The combination of strong buy/sell ratio and multiple buyers suggests insiders see attractive risk/reward. Consider this alongside fundamental analysis for confirmation.